Title: Hotels by Americinn in Byron from CA $117 | Expedia.ca [Byron Travel Guide](https://expedia.ca/Byron.dx553248623858895563)[Hotels in Byron](https://expedia.ca/Byron-Hotels.d553248623858895563.Travel-Guide-Hotels)[Vacation Rentals in Byron](https://expedia.ca/Byron-Vacation-Rentals.d553248623858895563.Travel-Guide-VacationRentals)[Flights to Byron](https://expedia.ca/Cheap-Flights-To-Byron.d553248623858895563.Travel-Guide-Flights)[Byron Car Rentals](https://expedia.ca/Car-Rentals-In-Byron.d553248623858895563.Car-Rental-Guide)[Byron Vacation Packages](https://expedia.ca/Byron.d553248623858895563.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Americinn in Byron from CA $117 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=553248623858895563&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Byron Americinn Hotels ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/8d7f7147.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/3bd995bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/493f76e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic Rochester 8.2/10 Very good (1121) "Was great for a stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) eric CA $102 CA $117 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Indoor pool, open 7:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/be097c9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/315a0f0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/881774df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/d84f2755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Rochester 8.8/10 Excellent (1002) "Clean rooms, friendly staff, good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Della CA $112 CA $129 total includes taxes & fees Dec 17 - Dec 18 [](https://www.expedia.ca/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=553248623858895563&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels-Americinn.0-0-d553248623858895563--bAmericinn.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FByron-Hotels-Americinn.0-0-d553248623858895563--bAmericinn.Travel-Guide-Filter-Hotels) ## Top Byron Hotel Reviews ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "We had a wonderful stay!" [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Construction " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![Hotel Indigo Rochester – Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010_y.jpg) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG 10/10 Excellent "Room was clean and comfortable. Skyway system was great for getting to Mayo as it was rainy, windy, and snowy. Lots of eating options and shopping nearby." [](https://expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Everything was perfect. Beautiful safe and comfortable " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "Clean and quiet. Great breakfast" [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![EVEN Hotel Rochester - Mayo Clinic Area by IHG](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd_y.jpg) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG 10/10 Excellent "Very comfortable and newly updated. " [](https://expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Best Western Rochester Hotel Mayo Clinic Area/St. Mary's](https://images.trvl-media.com/lodging/1000000/10000/3700/3682/w3836h2559x4y0-f5ee734c_y.jpg) ### Best Western Rochester Hotel Mayo Clinic Area/St. Mary's 10/10 Excellent "Yes" [](https://expedia.ca/Rochester-Hotels-Best-Western-Rochester-Hotel-Mayo-Clinic-AreaSt-Marys.h3682.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "We were able to use the subway system to the Mayo Clinic and back to the hotel without going outside. This was a plus since it was cold and rainy weather. Our room was clean. Breakfast gave a good variety of choices." [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/3600/3556/b33056f7_y.jpg) ### Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area 10/10 Excellent "The staff here were the most kind, caring, efficient and joyful staff that we've encountered. The hotel was immaculate, but a bit dated. Twigs Restaurant, in the hotel, had amazing food! We highly recommend it for any meal. Breakfast had a large variety of foods, drinks, etc. and was well maintained. We were only blocks away from the Mayo Clinic for appointments, tours, and could easily walk and enjoy all the architecture in the neighborhood! The shuttle service was quick, efficient and clean, and a nice, comfortable ride. There are plenty of stores & restaurants nearby." [](https://expedia.ca/Rochester-Hotels-Centerstone-Plaza-Hotel-Soldiers-FieldMayo-Clinic-Area.h3556.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Northwest](https://www.expedia.ca/4Star-Northwest-Rochester-Hotels.s40-n900102874825277440-0.Travel-Guide-Filter-Hotels) - [Hotels near Apache Mall](https://www.expedia.ca/Apache-Mall-Hotels.0-l6188936-0.Travel-Guide-Filter-Hotels) - [Hyatt Hotels in Apple Valley](https://www.expedia.ca/Apple-Valley-Hotels-Hyatt-Hotels.0-0-d6003--bHyattHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bancroft](https://www.expedia.ca/Bancroft-Minneapolis-St-Paul-Hotels-Hilton-Hotels.0-n553248635976472057-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bayport](https://www.expedia.ca/Bayport-Hotels-Hilton-Hotels.0-0-d3000442965--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Accor Hotels in Bloomington](https://www.expedia.ca/Bloomington-Hotels-Accor-Hotels.0-0-d6287--bAccorHotels.Travel-Guide-Filter-Hotels) - 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[Flights from Anchorage to Southeast Minnesota](https://www.expedia.ca/lp/flights/178230/6233996/anchorage-to-southeast-minnesota) - [Flights from Boston to Southeast Minnesota](https://www.expedia.ca/lp/flights/178239/6233996/boston-to-southeast-minnesota) - [Flights from Las Vegas to Southeast Minnesota](https://www.expedia.ca/lp/flights/178276/6233996/las-vegas-to-southeast-minnesota) - [Flights from Portland to Southeast Minnesota](https://www.expedia.ca/lp/flights/178299/6233996/portland-to-southeast-minnesota) - [Flights from San Antonio to Southeast Minnesota](https://www.expedia.ca/lp/flights/178303/6233996/san-antonio-to-southeast-minnesota) - [Flights from Seattle to Southeast Minnesota](https://www.expedia.ca/lp/flights/178307/6233996/seattle-to-southeast-minnesota) - [Flights from Tampa to Southeast Minnesota](https://www.expedia.ca/lp/flights/602996/6233996/tampa-to-southeast-minnesota) - [Visit Kasson](https://www.expedia.ca/Kasson.dx6035256) - [Visit Kutzky Park](https://www.expedia.ca/Rochester-Kutzky-Park.dx553248635976473564) - 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