5 Stars Hotels in Santiago, Santiago Metropolitan Region from CA $126
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Santiago 5 Star Hotels
Our top choices for Santiago 5-star hotels
1. Mandarin Oriental, Santiago
Mandarin Oriental, Santiago
2. The Ritz-Carlton, Santiago
The Ritz-Carlton, Santiago
3. W Santiago
W Santiago
4. NH Collection Plaza Santiago
NH Collection Plaza Santiago
5. Noi Vitacura
Noi Vitacura
6. The Singular Santiago
The Singular Santiago
7. Pullman Santiago Vitacura
Pullman Santiago Vitacura
8. LUUM by Norus
LUUM by Norus
Explore similar 4-star hotels
Holiday Inn Santiago - Airport Terminal by IHG
Santiago and related destinations
Nestled between snow-capped Andes and coastal ranges, this vibrant capital rewards visitors with world-class museums and bustling markets at Plaza de Armas. Take the funicular up San Cristóbal Hill for panoramic city views, then explore bohemian Bellavista's colourful streets and sample wines at nearby Maipo Valley vineyards.
Top Santiago Hotel Reviews
Mandarin Oriental, Santiago
Find out more about Santiago
Five Star Hotels in Santiago
There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Santiago so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Santiago and get ready to be pampered like never before.
Get a Great Deal on 5-Star Hotels in Santiago
Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.
Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.
Make Your Escape to Santiago
The results are in, and Santiago 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Santiago! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Santiago today and settle down in the lap of luxury tomorrow.
Frequently asked questions
Explore a world of travel with Expedia
- Barrio Italia Hotels
- Hotels near Plaza de Armas
- Las Condes Hotels
- La Florida Hotels
- Hotels with Early Check-in in Santiago Metropolitan Region
- Hotels near Parque Arauco Mall
- El Golf Hotels
- Boutique Hotels in Providencia
- Historic Hotels in Santiago
- Bellas Artes Hotels
- Four Seasons Hotels in Santiago
- Boutique Hotels in Santiago
- La Dehesa Hotels
- Hotels with Free Airport Shuttle in Santiago
- Luxury Hotels in Santiago
- Hotel Wedding Venues Hotels in Santiago
- Hotels with Free Airport Shuttle in Downtown Santiago
- Cheap Hotels in Santiago
- Peñalolén Hotels
- Downtown Santiago Hotels
- Hotels near Arturo Merino Benitez
- Hostels in Santiago
- Recoleta Hotels
- Spa Hotels in Santiago
- Ñuñoa Hotels
- Renca Hotels
- Cerrillos Hotels
- Santiago Hotels
- Bellavista Hotels
- Lastarria Hotels
- Historic Hotels in Santiago Metropolitan Region
- B&B in Santiago
- Lgbt Friendly Hotels in Santiago
- Hotels near Espacio Riesco Convention and Exhibition Center
- La Reina Hotels
- Hotels near Peru Plaza
- Providencia Hotels
- Flights from Victoria (YYJ) to Santiago (SCL)
- Flights from Buenos Aires (EZE) to Santiago (SCL)
- Flights from Toronto (YYZ) to Santiago (SCL)
- Flights from Montreal (YUL) to Santiago (SCL)
- Flights from Ottawa (YOW) to Santiago (SCL)
- Flights from Moncton (YQM) to Santiago (SCL)
- Flights from Kelowna (YLW) to Santiago (SCL)
- Flights from Halifax (YHZ) to Santiago (SCL)
- Flights from Los Angeles (LAX) to Santiago (SCL)
- Flights from El Calafate (FTE) to Santiago (SCL)
- Flights from Lima (LIM) to Santiago (SCL)
- Flights from Mexico City (MEX) to Santiago (SCL)
- Flights from Rio de Janeiro (RIO) to Santiago (SCL)
- Flights from Cancun (CUN) to Santiago (SCL)
- Flights from Mendoza (MDZ) to Santiago (SCL)
- Flights from Puerto Natales (PNT) to Santiago (SCL)
- Flights from São Paulo (GRU) to Santiago (SCL)
- Flights from Miami (MIA) to Santiago (SCL)
- Flights from Calgary (YYC) to Santiago (SCL)
- Flights from Auckland (AKL) to Santiago (SCL)
- Flights to Santiago
- Flights from Edmonton (YEG) to Santiago (SCL)
- Flights from Bogotá (BOG) to Santiago (SCL)
- Flights from Sydney (SYD) to Santiago (SCL)
- Flights from Punta Arenas (PUQ) to Santiago (SCL)
- Flights from Winnipeg (YWG) to Santiago (SCL)
- Flights from Vancouver (YVR) to Santiago (SCL)
- Flights from Cusco (CUZ) to Santiago (SCL)
- Flights from Saskatoon (YXE) to Santiago (SCL)
- Flights from New York (JFK) to Santiago (SCL)
- Visit Ñuñoa
- Visit Pudahuel
- Museum of Memory and Human Rights
- National Museum of Natural History
- Bicentennial Park
- Los Leones Golf Club
- Former National Congress
- Las Condes Vacations
- San Francisco Church
- San Cristobal Hill
- Metropolitan Cathedral
- Santa Lucia Hill
- Municipal Theatre of Santiago
- Visit Las Condes
- National History Museum
- Santiago Vacations
- Visit Downtown Santiago
- El Golf Vacations
- Plaza de Armas
- Visit Santiago
- Visit Santiago Metropolitan Region
- Museum of Contemporary Art
- Visit Barrio Italia
- Santiago Metropolitan Park
- Visit Bellavista
- Palacio de la Moneda
- Costanera Center