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Featured Santiago Luxury Hotels

See all 643 Hotels in Santiago
The Singular Santiago

The Singular Santiago

Merced 294, Santiago
5.0 out of 5.0
4.8 out of 5 (127 reviews)
Singular Beautiful boutique hotel with friendly staff.Good restaurant & rooftop bar with tapas style food. Rooms & hotel very well maintained with fine furniture & artwork.
  13 Dec 2017

C$410

C$410
Noi Vitacura

Noi Vitacura

Av. Nueva Costanera 3736, Santiago
5.0 out of 5.0
4.4 out of 5 (191 reviews)
Excellent Good Upgraded to a Great Room! Service was exceptional.
  16 May 2017

C$231

C$231
Renaissance Santiago Hotel

Renaissance Santiago Hotel

Avenida Kennedy 4700, Santiago
5.0 out of 5.0
4.6 out of 5 (198 reviews)
Very nice, quiet, amazing staffVisited on my birthday, staff went above and beyond to make it special. Very helpful arranging tourist activities, took care of me, I was able to see exactly what I'd hoped to. Short walk to wonderful mall with lots of restaurants. Close to wonderful large park behind mall. Located in nice neighborhood. ...
  12 Sep 2017

C$194

C$194
Lastarria Boutique Hotel

Lastarria Boutique Hotel

Coronel Santiago Bueras 188, Santiago
5.0 out of 5.0
4.6 out of 5 (233 reviews)
Great location for exploring SantiagoA wonderful relaxing place to stay after a day's sightseeing
  14 Dec 2017

C$296

C$296
Hotel Santiago

Hotel Santiago

Kennedy Avenue #4601, Santiago
5.0 out of 5.0
4.4 out of 5 (327 reviews)
It’s a nice place It’s a nice place, the building has good bones... change management from Hyatt to mandarin hotel... the place under Hyatt become tired look so new mandarin is doing a renovation to bring back the flash from early years this great building... when is completed will be incredibly now still a great ...
  18 Nov 2017

C$324

C$324
San Cristobal Tower, a Luxury Collection Hotel

San Cristobal Tower, a Luxury Collection Hotel

Josefina Edwards De Ferrari 0100, Santiago
5.0 out of 5.0
4.5 out of 5 (49 reviews)
Good location Quick check in,very clean and extremely helpful staff. Upgraded to a balcony suite on 17th floor with a breathtaking view. Being an spg member, suite was discounted. Highly recommend to everyone.
  14 Dec 2017

C$307

C$307
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

Calle El Alcalde 15, Santiago
5.0 out of 5.0
4.7 out of 5 (146 reviews)
Great Hotel Here in Santiago for a couple days on our way to Atacama. First class all the way; building, service and room.
  6 Dec 2017

C$436

C$436
Boulevard Suites Hotel

Boulevard Suites Hotel

Avenida Kennedy 5749, Santiago
5.0 out of 5.0
4.5 out of 5 (66 reviews)
Huge rooms, clean, renovated, great! Only issue was the room wasn't cleaned until 5pm.
  25 Oct 2015

C$204

C$204
Radisson Blu Santiago La Dehesa

Radisson Blu Santiago La Dehesa

12851 Comandante Malbec, Lo Barnechea, Santiago
5.0 out of 5.0
4.4 out of 5 (230 reviews)
Not too executive. The room has a problem with the sink. When I called room service for lunch no body picked up. Because of that I had to cross the street to the gas station, waste my time and eat very badly. The stuff of the hotel was nice, but the guy of the door wasn´t so nice. Too Chilean, maybe you need to put ...
  16 Oct 2017

C$195

C$195
InterContinental Santiago

InterContinental Santiago

Av. Vitacura 2885, Santiago
5.0 out of 5.0
3.8 out of 5 (150 reviews)
Nice hotel good location Booked last minute was very pleased for my short stay
  23 Jun 2017

C$119

C$119
Map

Recently booked Santiago hotels

InterContinental Santiago
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A weekend away keeps your stress at bay, especially when you're spending time in Santiago. Marvelous activities, delicious eats, and chances to take fantastic pictures: these are just some of the reasons to take a vacation to Santiago. You'll enjoy the most popular performances, treat yourself to decadent dishes, and eye-guzzle the most popular attractions in the region. Where else would you stay but a luxury hotel? Anything less than the best is for the birds, so book your elegant hotel in Santiago on Expedia.com right now and start your excursion off on the right (well-dressed) foot.

Booking Santiago Vacations

It turns out plenty of folks have decided to have set down roots -- how is that for proof that Santiago is full of an intoxicating array of activities? No matter what brings you to Santiago, the destination always delivers. Santiago is full of dreamy hotels on top of appealing attractions, so it's no surprise that travelers come back. Book early to get the best room!

An upscale vacation begs for you to explore day spas, art, and local museums. When you book your travel on Expedia.com, it's all at your fingertips. Thanks to our great rates on hotels, you can always afford to check out the region's most interesting sights. After many hours of exploring the city, your luxury hotel is waiting with spectacular food and upscale amenities. Take advantage of amenities like an incredible balcony view or hot tub before the day is over. The luxury rooms and suites in Santiago will have you feeling the relaxation in no time.

Luxury Hotels in Santiago

When you’ve got your heart set on a sophisticated escape in Santiago, Expedia.com is here to save the day. Browse the abundance of real traveler reviews on more than a dozen hotels until you spot the perfect place to stay. 5-Star hotels treat you right, offering things like concierge services and private kitchens. Some of the city's luxury accommodations even feature gigantic penthouses, while others have exquisite in-room dining. Book your dream hotel in Santiago now, and soon you'll be soaking up luxury in style!