4 Stars Hotels in Clayton, St. Louis from CA $148
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Top Clayton 4 Star Hotels
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.
Four Seasons Hotel St Louis
999 North Second Street, St. Louis, MO
The price is CA $509 per night from Mar 30 to Mar 31
CA $509
CA $596 total
includes taxes & fees
Mar 30 - Mar 31
9.4/10 Exceptional! (897 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent Reviews in ClaytonExpedia verified reviews
5/5 Excellent
"We enjoyed out 3 night stay. Room was clean and comfortable. Staff was very friendly and helpful. It's a unique hotel with interesting displays and decorations."
A verified traveller stayed at Moonrise Hotel
Posted 1 day ago
Hotels in Clayton Neighborhoods
Hotels near Popular Clayton Attractions
- St. Louis Union Station
- Busch Stadium
- Gateway Arch
- St. Louis Zoo
- Washington University in St. Louis
- Enterprise Center
- Mississippi River
- Barnes Jewish Hospital
- Dome at America’s Center
- Ameristar Casino St. Charles
- Hollywood Casino Amphitheatre
- Westport Plaza
- St. Louis University
- Fox Theater
- America's Center Convention Complex
- Missouri Botanical Gardens and Arboretum
- Lindenwood University
- St Charles Convention Center
More Hotel Options in Clayton
More Popular Hotels in St. Louis
- Hilton St. Louis at the Ballpark
- Pear Tree Inn St. Louis Airport
- Casino Queen Hotel
- The Last Hotel
- Moonrise Hotel
- Pear Tree Inn St. Louis Near Union Station
- Angad Arts Hotel
- Renaissance St. Louis Airport Hotel
- Forest Park Hotel by MDR
- Drury Inn & Suites St. Louis Union Station
- Live by Loews - St.Louis
- River City Casino & Hotel
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Aviator Hotel & Suites South I-55, BW Signature Collection
- The Wildwood Hotel
- Hampton Inn St. Louis-Downtown (At the Gateway Arch)
- La Quinta Inn & Suites by Wyndham St. Louis Westport
- Marriott St. Louis Grand
- Residence Inn by Marriott St Louis Downtown