Clayton
St. Louis
Visit Clayton
Stay near popular Clayton attractions
Things to do
St. Louis Ghost Tour: Sinister Sins & Shadows
CA $34
per adult
100% of travellers recommend
StL's Signature "Sights and Bites" - Private Tour in St. Louis
CA $246
per adult
Lemp Haunted Neighborhood Walking Tour
CA $35
per adult
84% of travellers recommend
Clayton Hotel Deals
Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Sep 6 to Sep 7
CA $128
CA $150 total
Sep 6 - Sep 7
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,375 reviews)
"Always clean, staff friendly, breakfast is good."
Reviewed on Aug 24, 2026
Le Méridien St. Louis Clayton
7730 Bonhomme Ave St. Louis MO
The price is CA $209 per night from Aug 29 to Aug 30
CA $209
CA $246 total
Aug 29 - Aug 30
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
AC Hotel St. Louis Clayton
227 South Central Ave St. Louis MO
The price is CA $167 per night from Sep 13 to Sep 14
CA $167
CA $195 total
Sep 13 - Sep 14
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9.2/10 Wonderful! (375 reviews)
"The property was clean and staff was courteous and the location was great"
Reviewed on Aug 24, 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
216 N Meramec Ave St. Louis MO
The price is CA $179 per night from Aug 30 to Aug 31
CA $179
CA $211 total
Aug 30 - Aug 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, a fitness center, and parking (surcharge). Our guests praise the helpful staff ...
Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
The price is CA $185 per night from Aug 28 to Aug 29
CA $185
CA $218 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,256 reviews)
"This is our 2nd year staying here for the Banana games that came to St Louis. I love your hotel. It’s clean. It’s friendly. The location is great. But for the 2nd year in a row I have to complain about the sheets! For a nice hotel and a $500 weekend your sheets are TERRIBLE! It feels like we are ..."
Reviewed on Aug 24, 2026
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
The price is CA $134 per night from Aug 31 to Sep 1
CA $134
CA $197 total
Aug 31 - Sep 1
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (2,248 reviews)
"Good location to events nice shuttle worth the money room clean ."
Reviewed on Aug 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Clayton
Find the best Clayton areas and neighborhoods for the activities you enjoy most.
Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.
Central West End
The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.
Photo by Terry Eaves
Open Photo by Terry Eaves
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.
Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.
St. Charles Historic District
St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Lewis & Clark Boathouse and Nature Center while you're in town.
