Title: Top 10 Hotels Near 22nd Street Station from CA $156 | Expedia.ca [Potrero Hill Travel Guide](https://expedia.ca/San-Francisco-Potrero-Hill.dx506137)[Potrero Hill Car Rentals](https://expedia.ca/Car-Rentals-In-Potrero-Hill.d506137.Car-Rental-Guide)[Potrero Hill Vacation Packages](https://expedia.ca/Potrero-Hill.d506137.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Feb 5 - Feb 6](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 6 - Feb 7](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6173593&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for 22nd Street Station hotels ![Tapas bar](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/58dd339c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/26f4395c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/44e1b72d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### LUMA Hotel San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) 1.9 km from 22nd Street Station 9.6/10 Exceptional (2,454 reviews) "Overall a great hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley CA $299 CA $352 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/91986f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/b089b5be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/6945eefa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 16 per person)](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/f9d4387a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place San Francisco Downtown [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) 2.3 km from 22nd Street Station 9.4/10 Exceptional (1,981 reviews) "Check-in and check-out went smoothly with staff, clean rooms and overall nice hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Giovanna CA $245 CA $288 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/004f15cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e4464a9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/e96af726.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Park View](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/3c515aa8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel VIA [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) 2.4 km from 22nd Street Station 9.2/10 Wonderful (1,513 reviews) "Great location and staff! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Monica CA $245 CA $288 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/d4275eec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/439430c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/791b3727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/12000000/11470000/11462200/11462191/9c929833.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Noe's Nest Bed and Breakfast [](https://www.expedia.ca/San-Francisco-Hotels-Noes-Nest-Bed-And-Breakfast.h11462191.Hotel-Information) 2.7 km from 22nd Street Station 9.4/10 Exceptional (123 reviews) "A very nice and comfortable B&B place to stay..... nestled in the Noe Valley section of San Francisco" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lester CA $321 CA $374 total includes taxes & fees Feb 17 - Feb 18 [](https://www.expedia.ca/San-Francisco-Hotels-Noes-Nest-Bed-And-Breakfast.h11462191.Hotel-Information) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/da85ef17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/f7c5f6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/3dcd0db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental San Francisco by IHG [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) South of Market, 2.9 km from 22nd Street Station 9.2/10 Wonderful (1,087 reviews) "Very nice hotel, great amenities and excelente service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica CA $252 CA $352 total includes taxes & fees Feb 13 - Feb 14 [](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information) ![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/abad6cd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Fireplace (Landmark View) | Living area](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/3012b8f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/5931a034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/5335e149.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canopy by Hilton San Francisco SoMa [](https://www.expedia.ca/San-Francisco-Hotels-Canopy-By-Hilton-San-Francisco-SoMa.h27110513.Hotel-Information) South Park, 2.9 km from 22nd Street Station 9.0/10 Wonderful (1,000 reviews) "Great place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raquel CA $231 CA $271 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/San-Francisco-Hotels-Canopy-By-Hilton-San-Francisco-SoMa.h27110513.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/febae001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/00836df3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/80647523.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/97000000/96820000/96810700/96810663/bf217857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fiona [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Fiona.h96810663.Hotel-Information) South of Market, 2.8 km from 22nd Street Station 8.6/10 Excellent (1,012 reviews) "Nice size room , comfy bed and nice staff and hotel convenient parking " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shawna CA $109 CA $156 total includes taxes & fees Feb 10 - Feb 11 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Fiona.h96810663.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/1656ff5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/100ffc4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/da0bd574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Clancy, Autograph Collection by Marriott [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) South Park, 3.2 km from 22nd Street Station 9.2/10 Wonderful (1,002 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey CA $231 CA $329 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/7fe7eb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/0c9770db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/f11ecdc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse, 1 Bedroom, City View | Living room](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/3afd96af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### W San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) South Park, 3.2 km from 22nd Street Station 9.0/10 Wonderful (1,002 reviews) "This hotel exceeded all expectations in every way. The accommodations, service, and atmosphere were exceptional. I truly enjoyed my stay and would not hesitate to return." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andres CA $228 CA $317 total includes taxes & fees Mar 6 - Mar 7 [](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information) ![2 bars/lounges, lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/18400/18320/71b5e6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/18400/18320/08a6e174.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/18400/18320/6c69848f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18400/18320/99010890.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zetta San Francisco [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zetta-San-Francisco.h18320.Hotel-Information) South of Market, 3.1 km from 22nd Street Station 8.8/10 Excellent (1,000 reviews) "The staff was incredibly kind especially after a super long flight, the room was clean and cozy the amenities were good plus the area itself felt safe. Would absolutely stay here again. Special shout out to " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandra CA $187 CA $276 total includes taxes & fees Mar 1 - Mar 2 [](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zetta-San-Francisco.h18320.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20®ionId=6173593&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top 22nd Street Station Hotel Reviews ![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg) ### Club Quarters Hotel in San Francisco 10/10 Excellent "Clean room. Nice staff!" [](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information) ![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg) ### Holiday Inn Golden Gateway by IHG 10/10 Excellent "Clean room " [](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information) ![Chancellor Hotel on Union Square](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c_y.jpg) ### Chancellor Hotel on Union Square 10/10 Excellent "Great location " [](https://expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information) ![Handlery Union Square Hotel](https://images.trvl-media.com/lodging/1000000/10000/6700/6666/b8dfc462_y.jpg) ### Handlery Union Square Hotel 10/10 Excellent "Friendly staff great location " [](https://expedia.ca/San-Francisco-Hotels-Handlery-Union-Square-Hotel.h6666.Hotel-Information) ![Fairmont San Francisco](https://images.trvl-media.com/lodging/1000000/20000/18200/18200/6f6889e4_y.jpg) ### Fairmont San Francisco 10/10 Excellent "Nice residence and nice place." [](https://expedia.ca/San-Francisco-Hotels-Fairmont-San-Francisco.h18200.Hotel-Information) ![Hotel Zephyr San Francisco](https://images.trvl-media.com/lodging/10000000/9870000/9868900/9868852/fd976170_y.jpg) ### Hotel Zephyr San Francisco 10/10 Excellent "It was a great place for kids. The room was wonderful. The location was perfect. The ping pong and shuffle board open 24/7 was top notch and the free smores kits were a bonus. " [](https://expedia.ca/San-Francisco-Hotels-Hotel-Zephyr-San-Francisco.h9868852.Hotel-Information) ![Marriott Vacation Club®, San Francisco](https://images.trvl-media.com/lodging/38000000/37390000/37382500/37382494/0671fcfa_y.jpg) ### Marriott Vacation Club®, San Francisco 10/10 Excellent "Hotel was clean" [](https://expedia.ca/San-Francisco-Hotels-Marriott-Vacation-Club-Pulse.h37382494.Hotel-Information) ![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg) ### Hilton San Francisco Financial District 10/10 Excellent "Savvy, clean, sleek in a very clean China town. I love the cars a aialbe to pick you up and drop off as part of the guest services. The breakfast was not buffet style but still covered side orders of fruit and drinks. It was a good deal to have it connected with your room purchase. The view was breathe taking--- clean, spacious and wonderful. " [](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information) ![Hyatt Centric Fisherman's Wharf San Francisco](https://images.trvl-media.com/lodging/1000000/30000/22500/22500/1d699bf3_y.jpg) ### Hyatt Centric Fisherman's Wharf San Francisco 10/10 Excellent "The room was so comfortable and clean! The beds are very soft and cozy. The front desk staff is super friendly. Location is amazing to walk to pier 39 and access lots of all that is San Francisco!" [](https://expedia.ca/San-Francisco-Hotels-Hyatt-Centric-Fishermans-Wharf-San-Francisco.h22500.Hotel-Information) ## Frequently asked questions ### What's the area like around 22nd Street Station? ### What's the best place to stay close to 22nd Street Station? ### How many hotels will I find near 22nd Street Station? ### What can I see and do near 22nd Street Station? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [Aparthotels in 16th Street Mission Station ](https://www.expedia.ca/16th-Street-Mission-Station-Apart-Hotels.d6176452-aaApartHotels.Travel-Guide-Accommodation) - [Hotels near 16th Street Mission Station ](https://www.expedia.ca/16th-Street-Mission-Station-Hotels.d6176452.Travel-Guide-Hotels) - [Villas in 16th Street Mission Station ](https://www.expedia.ca/16th-Street-Mission-Station-Villas.d6176452-aaVillas.Travel-Guide-Accommodation) - [Aparthotels in 20th Street Station ](https://www.expedia.ca/20th-Street-Station-Apart-Hotels.d553248635996308275-aaApartHotels.Travel-Guide-Accommodation) - 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[Noble House Hotels in Mission Bay ](https://www.expedia.ca/Mission-Bay-San-Francisco-Hotels-Noble-House.0-n553248635976008622-0--bNobleHouse.Travel-Guide-Filter-Hotels) - [Mission Bay Hotels ](https://www.expedia.ca/Mission-Bay-San-Francisco-Hotels.0-n553248635976008622-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Mission District ](https://www.expedia.ca/Mission-District-San-Francisco-Hotels-Boutique-Hotel.0-n134035-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Mission District ](https://www.expedia.ca/Mission-District-San-Francisco-Hotels-Cheap-Hotels.0-n134035-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Mission District ](https://www.expedia.ca/Mission-District-San-Francisco-Hotels-Couples-Resorts-Hotels.0-n134035-0-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Family Hotels in Mission District ](https://www.expedia.ca/Mission-District-San-Francisco-Hotels-Family-Hotel.0-n134035-0-tFamilyHotel.Travel-Guide-Filter-Hotels) - 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