Title: Pet-friendly Vacations in Upstate South Carolina 2026 | Expedia.ca ![](https://images.trvl-media.com/place/144669/e945b35d-16b4-408c-818b-68622e164446.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Upstate South Carolina Pet-friendly Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by RVLuckyorWhat - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## 4 Night Pet-friendly holidays in Upstate South Carolina Price found within the past 48 hours. Click for updated prices. ![Extended Stay America Select Suites Greenville Haywood Mall](https://images.trvl-media.com/lodging/1000000/50000/43500/43460/b2770f12_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Extended Stay America Select Suites Greenville Haywood Mall CA $646 per person Mar 25 - Mar 29 found 1 day ago Roundtrip non-stop flight included Buffalo (BUF) to Greenville (GSP) 7/10 Good! (541 reviews) Great price for an extended stay. The room is spacious, clean and cool staff Reviewed on Jan 14, 2026 ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### La Quinta Inn & Suites by Wyndham Greenville Haywood CA $663 per person Mar 25 - Mar 29 found 1 day ago Roundtrip non-stop flight included Buffalo (BUF) to Greenville (GSP) 7.4/10 Good! (1,110 reviews) Great service, good price, staff very friendly Reviewed on Dec 26, 2025 ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Best Western Plus Greenville I-385 Inn & Suites CA $759 per person Mar 25 - Mar 29 found 1 day ago Roundtrip non-stop flight included Buffalo (BUF) to Greenville (GSP) 9.2/10 Wonderful! (1,396 reviews) Loved our room, we had a king suite excellent modern decor.. The bed was super comfortable. The buffet breakfast had a great selection of food and the dining area was a nice decor and size. The staff was super friendly and helpful Reviewed on Jan 12, 2026 Don't see what you're looking for? See all available trips from Columbus to Upstate South Carolina [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-02-15/2026-02-22/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GSP&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Pet-friendly Hotels in Upstate South Carolina ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Greenville 45 W Orchard Park Dr Greenville SC - 1 hour drive from Clemson University Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ... 8.2/10 Very Good! (1,009 reviews) Convenient and clean Reviewed on Jan 11, 2026 [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Embassy Suites Greenville Golf Resort & Conference Center 670 Verdae Blvd Greenville SC - 1 hour drive from Clemson University Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ... 9/10 Wonderful! (1,025 reviews) I had a cleaning issue. I informed the hotel before my stays that have chronic allergies/ asthma to make sure my room was deep cleaned because I’m highly allergic to dogs, cats, dust, etc. just about every night I would start coughing and choking. I woke checked over my headboard, picture frame and ... Reviewed on Jan 8, 2026 [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grand Bohemian Lodge Greenville, Autograph Collection 44 EAST CAMPERDOWN WAY Greenville SC - 1 hour drive from Clemson University Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ... 9.4/10 Exceptional! (435 reviews) Great room and view if falls Reviewed on Jan 11, 2026 [](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) [See all 2,928 properties in Upstate South Carolina](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6057939) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Upstate South Carolina ](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[ Upstate South Carolina Hotels ](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[ Upstate South Carolina Vacation Rentals ](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[ Upstate South Carolina Car Rentals ](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[ Upstate South Carolina Vacations ](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides)[ Things to do in Upstate South Carolina ](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app