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Pet-friendly Hotels in Upstate South Carolina

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

1 hour drive from Clemson University

Book a stay at this spa hotel in Greenville. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the ...

9.6/10 Exceptional! (526 reviews)

"Perfect location to visit downtown , staff was very helpful and valet was top notch. We stayed in a suite and had the best view of the falls , great property."

Reviewed on Jul 11, 2026

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

1 hour drive from Clemson University

Book a stay at this golf resort in Greenville. Enjoy free breakfast, a golf course, and a free airport shuttle. Our guests praise the breakfast and the helpful ...

9/10 Wonderful! (1,306 reviews)

"Courteous, helpful staff. Great amenities."

Reviewed on Jul 9, 2026

Hyatt Regency Greenville

220 N Main St Greenville SC

1 hour drive from Clemson University

Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and 2 restaurants. Our guests praise the helpful staff and the clean ...

8.8/10 Excellent! (1,012 reviews)

"We really enjoyed our stay at this hotel! The hotel has a restaurant, café, and bar, which was very convenient. The staff at check-in were very kind and helpful, and the room was nice as well! I do wish breakfast had been included in the room rate, but otherwise, it was a great place to stay!"

Reviewed on Jul 13, 2026

See all 3,055 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.