Title: Book The Best Hotels in Upstate South Carolina for 2026 from CA $95 - Fully Refundable Options - Expedia.ca

[Upstate South Carolina Travel Guide](https://expedia.ca/Upstate-South-Carolina.dx6057939)[Vacation Rentals in Upstate South Carolina](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Upstate South Carolina Car Rentals](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides)

![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Visit Greenville, South Carolina

![](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Upstate South Carolina

Spa

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&amenities=SPA_ON_SITE)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&amenities=HOT_TUB)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&amenities=POOL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&amenities=PETS)

Cabin

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&lodging=CABIN)

Farm

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&lodging=AGRITOURISM)

Chalet

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&lodging=CHALET)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&amenities=WATER_PARK)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&lodging=COTTAGE)

Villa

[](https://www.expedia.ca/Hotel-Search?destination=Upstate+South+Carolina%2C+South+Carolina%2C+United+States+of+America&regionId=6057939&latLong=34.772137%2C-82.278365&adults=2&startDate=2026-03-14&d1=2026-03-14&endDate=2026-03-16&d2=2026-03-16&lodging=VILLA)

## Check prices for these dates

Tonight

[Feb 28 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-02-28&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 1 - Mar 2](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-01&endDate=2026-03-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6057939&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Upstate South Carolina hotels

![Free daily full breakfast](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/589dc000.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a5e4dea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/a9c6228a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/72000000/71520000/71515100/71515054/b9808144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Gaffney by IHG

[](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information)

Gaffney

8.8/10

Excellent

(449 reviews)

"Great people n place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Janice

CA $104

CA $113 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Gaffney-Hotels-Holiday-Inn-Express-Gaffney.h71515054.Hotel-Information)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Living area](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/3f2de599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Camp Cedar

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Pickens

10/10

Exceptional

(2 reviews)

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katlynn

CA $128

CA $256 total

includes taxes & fees

Mar 9 - Mar 10

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/81c4f249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/f6f7c8c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business centre](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/16b3def6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seneca Clemson Area US-123

[](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

Downtown

8.0/10

Very good

(681 reviews)

"Everting was good"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Susan

CA $106

CA $125 total

includes taxes & fees

Mar 6 - Mar 7

[](https://www.expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/353a96bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/120fd9b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/14b9a4cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1460000/1453500/1453465/12e02e24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Easley

[](https://www.expedia.ca/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information)

Easley

9.2/10

Wonderful

(691 reviews)

"Friendly staff, very comfortable room, excellent hot breakfast."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Thomas

CA $167

CA $185 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Easley-Hotels-Hampton-Inn-Easley.h1453465.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/ac0c08fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Greenville I-385 Inn & Suites

[](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

Greenville

9.2/10

Wonderful

(1,442 reviews)

"The room was clean, staff was wonderful, quiet and convenient location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

CA $113

CA $125 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d93f55e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/9d9a13cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/2f127f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/69000000/68980000/68975500/68975422/d45e119a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Greer Greenville, SC

[](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information)

Greer

9.6/10

Exceptional

(434 reviews)

"Parking garage for hotel guests, location was great, hotel was clean, staff was great. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tyler

CA $217

CA $236 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Greer-Hotels-Hampton-Inn-Greer-Greenville.h68975422.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/67f2e81b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/9ab88731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/e439dee7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 restaurants, breakfast, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/990000/988800/988782/ea82fa69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spartanburg Marriott

[](https://www.expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information)

Spartanburg

8.6/10

Excellent

(1,000 reviews)

"great hotel! Clean and awesome restaurant!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alicia

CA $161

CA $179 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/Spartanburg-Hotels-Spartanburg-Marriott.h988782.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/83732283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/b202edd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/62fa3a56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/35000000/34330000/34323400/34323330/590fd43d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Seneca Clemson

[](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

Seneca

9.2/10

Wonderful

(810 reviews)

"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cindy

CA $153

CA $169 total

includes taxes & fees

Mar 9 - Mar 10

[](https://www.expedia.ca/Anderson-Hotels-Tru-By-Hilton-Seneca-Clemson.h34323330.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/5902a5ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast served](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/27046188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/7711c34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1340700/1340606/bb1bfaf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden Inn Anderson

[](https://www.expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information)

Anderson

9.0/10

Wonderful

(703 reviews)

"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sadie

CA $135

CA $150 total

includes taxes & fees

Mar 7 - Mar 8

[](https://www.expedia.ca/Anderson-Hotels-Hilton-Garden-Inn-Anderson.h1340606.Hotel-Information)

![Suite, Non Smoking](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/a3ff3e5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/043ecbeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/ee72685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/772de931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Suites Simpsonville - Greenville

[](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information)

Simpsonville

8.2/10

Very good

(796 reviews)

"Wonderful stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Barrie

CA $135

CA $148 total

includes taxes & fees

Mar 14 - Mar 15

[](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/9bab6d34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/3f88a754.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/227b33b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/850000/848800/848780/0160650e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

[](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

Anderson

9.0/10

Wonderful

(597 reviews)

"Clean, quiet, comfortable stay- staff is always friendly and helpful!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lori

CA $127

CA $141 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Anderson-Hotels-Holiday-Inn-Express-Hotel-Suites-Anderson-I-85.h848780.Hotel-Information)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/5cc3b6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/42b56840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/51a7c4d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/0d8d0617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Greenville Simpsonville

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

Simpsonville

9.0/10

Wonderful

(680 reviews)

"Quick check in, and the rooms were clean!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

DENNIS

CA $138

CA $152 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/8238721d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Double Beds, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/f2d60448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Greenville Golf Resort & Conference Center

[](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

Greenville

9.0/10

Wonderful

(1,084 reviews)

"Great staff, awesome property"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Annisha

CA $158

CA $174 total

includes taxes & fees

Mar 15 - Mar 16

[](https://www.expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/0304ce09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/5a8cea9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/573947b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Gaffney

[](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information)

Gaffney

8.8/10

Excellent

(682 reviews)

"Excellent all around "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

CA $158

CA $172 total

includes taxes & fees

Mar 22 - Mar 23

[](https://www.expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information)

![Free breakfast](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-f00c0668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/282fab11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/aa533fe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Clemson Hotel & Conference Center

[](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

Clemson

8.2/10

Very good

(1,006 reviews)

"Our room was very clean and the staff were very nice and courteous!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tina

CA $124

CA $138 total

includes taxes & fees

Mar 5 - Mar 6

[](https://www.expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/60d71ae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/3e3a13ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/330446c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/19100/19019/4f8e319f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Clemson - University Area

[](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information)

Clemson

8.2/10

Very good

(1,001 reviews)

"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Delaney

CA $131

CA $146 total

includes taxes & fees

Mar 4 - Mar 5

[](https://www.expedia.ca/Anderson-Hotels-Comfort-Inn-Suites-Clemson-University-Area.h19019.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/f08daaa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/c9a89e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/7636779c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28100/28087/d8583276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Points by Sheraton Spartanburg

[](https://www.expedia.ca/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information)

Spartanburg

9.4/10

Exceptional

(455 reviews)

"Friendly staff, clean rooms, excellent food! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ashley

CA $138

CA $153 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Spartanburg-Hotels-Four-Points-By-Sheraton-Spartanburg.h28087.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/b3b1b4a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/84ae320a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/1ac2fb4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251408/e7b52d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tru by Hilton Spartanburg

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information)

Spartanburg

9.2/10

Wonderful

(850 reviews)

"The place was perfect for our, trip"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ronald

CA $125

CA $139 total

includes taxes & fees

Mar 8 - Mar 9

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Tru-By-Hilton-Spartanburg.h48251408.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/54b1a852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/95b4cb26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/7e082995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/d789a59c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Clinton - Laurens I-26

[](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information)

Clinton

7.4/10

Good

(530 reviews)

"Super clean and quiet and staff was extremely nice and friendly"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

CA $85

CA $100 total

includes taxes & fees

Apr 1 - Apr 2

[](https://www.expedia.ca/Clinton-Hotels-Quality-Inn-Clinton.h26875.Hotel-Information)

![Hallway](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/4d00561c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cafe](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/893b2bfc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/d217b18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/20000000/19520000/19511400/19511329/cb83efe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Inn at Patrick Square

[](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information)

Clemson

9.8/10

Exceptional

(801 reviews)

"Clean room, great location, wonderful staff!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Joyce

CA $203

CA $226 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Anderson-Hotels-The-Inn-At-Patrick-Square.h19511329.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16&regionId=6057939&adults=2&sort=RECOMMENDED&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

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Members save up to 40% on hotels and homes. Plan this year’s big trip and save. 

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## Vacation Rentals in Upstate South Carolina

Cabin

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/afe0f510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Living area](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/3f2de599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/4d5d913d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Bedroom, Courtyard View | Front of property](https://images.trvl-media.com/lodging/123000000/122100000/122099800/122099740/f825207a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Camp Cedar

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Pickens

10/10

Exceptional

(2 reviews)

"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"

[](https://www.expedia.ca/Pickens-Hotels-Carolina-Camp-Cedar.h122099740.Hotel-Information)

Cabin

![View from property](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 1 Queen Bed (View) | Private kitchen](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/e935ccb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/cf119645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/ec2a8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

Seneca

9.8/10

Exceptional

(62 reviews)

"Excellent stay."

[](https://www.expedia.ca/Seneca-Hotels-Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information)

Apartment

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/d4764610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/26081583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/a232b415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107980000/107978100/107978043/53b6a5d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serene Travelers Rest Apartment: 7 Mi to Downtown!

[](https://www.expedia.ca/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information)

Travelers Rest

10/10

Exceptional

(1 review)

"The best time ever. My wife and I enjoyed our Honeymoon and stay here. We will come back every year for our Anniversary now and also to vacation here. The area was beautiful, quiet, and safe. We had everything we needed. No other vacation spot in South Carolina can compete. Thank you for our wonderful stay and perfect memories! "

[](https://www.expedia.ca/Travelers-Rest-Hotels-Serene-Travelers-Rest-Apartment-7-Mi-To-Downtown.h107978043.Hotel-Information)

Aparthotel

![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Vista Wedge Cottage | Private kitchen](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/fa38c3ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Station by Compo Hotels

[](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information)

Travelers Rest

10/10

Exceptional

(17 reviews)

"great place perfect for more privacy vs. a standard hotel"

[](https://www.expedia.ca/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information)

Mobile Home

![Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | In-room dining](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/e62d89db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/6f5c7f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin, 2 Bedrooms, Non Smoking (No Pets, Linens Included) | Living room](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/1853a44e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/10000000/9130000/9126600/9126575/dcda994e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Carolina Landing RV Resort - Caravan Park

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Fair Play

7.6/10

Good

(47 reviews)

"Lake "

[](https://www.expedia.ca/Fair-Play-Hotels-Carolina-Landing-RV-Resort-Caravan-Park.h9126575.Hotel-Information)

Aparthotel

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/61217476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/002ffe20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/2d11b158.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/70000000/69720000/69716800/69716747/464c71ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Greenville-Haywood Mall

[](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information)

Greenville

9.0/10

Wonderful

(206 reviews)

"Room was very clean and welcoming. The only staff we met was Mark, and he was absolutely wonderful and friendly. "

[](https://www.expedia.ca/Greenville-Hotels-StayAPT-Suites-Greenville-Haywood-Mall.h69716747.Hotel-Information)

Apartment

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![One Bedroom (Self Check-in with Virtual Front Desk)](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/21618793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/3786343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mint House Greenville Downtown by Kasa

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information)

Greenville Downtown

9.2/10

Wonderful

(797 reviews)

"Spotless wonderful stay"

[](https://www.expedia.ca/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information)

Cottage

![Signature Cottage, 2 Bedrooms | Living room](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/a4df93b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Cottage, 2 Bedrooms | Private kitchen](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/0d77f138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Cottage, 2 Bedrooms](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/9cd5859a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/90000000/89510000/89502700/89502605/b86441f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Clemson Memorabilia House

[](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information)

Clemson

9.8/10

Exceptional

(9 reviews)

"We enjoyed our stay, it was the perfect size for our family of four. "

[](https://www.expedia.ca/Clemson-Hotels-Clemson-Memorabilia-House.h89502605.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/83f2467b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/72e7e252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/43ded798.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119870000/119865300/119865212/9010a905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 8 Mi to Clemson: Peaceful Family Home w/ Yard

[](https://www.expedia.ca/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."

[](https://www.expedia.ca/Seneca-Hotels-8-Mi-To-Clemson-Peaceful-Family-Home-W-Yard.h119865212.Hotel-Information)

Cottage

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/784635bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/1767b060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/e4c6187d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/104000000/103710000/103707900/103707807/09b84ce7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waterfront Seneca Cabin \~ 4 Mi to Boat Launch!

[](https://www.expedia.ca/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"Beautiful and quaint cabin! Highly recommend, great view of the lake."

[](https://www.expedia.ca/Seneca-Hotels-Waterfront-Seneca-Cabin-4-Mi-To-Boat-Launch.h103707807.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/309d8bf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/ebe19f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/34ff4e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/114000000/113190000/113184500/113184450/86d9c4f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Deck, Grill & Dock Access: Lake Keowee Retreat!

[](https://www.expedia.ca/Seneca-Hotels-Deck.h113184450.Hotel-Information)

Seneca

10/10

Exceptional

(1 review)

"The best, perfect "

[](https://www.expedia.ca/Seneca-Hotels-Deck.h113184450.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/89d76ac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/3e1d7748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/6b65227c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98553800/98553702/506b693f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Waterfront Lake Hartwell Vacation Rental w/ Dock!

[](https://www.expedia.ca/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information)

Townville

10/10

Exceptional

(1 review)

[](https://www.expedia.ca/Townville-Hotels-Waterfront-Lake-Hartwell-Vacation-Rental-W-Dock.h98553702.Hotel-Information)

Cottage

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/e34f879b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/4f3ec318.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/54580926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537127/664f7ac0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 9 Mi to Devils Fork State Park: Getaway w/ Porch!

[](https://www.expedia.ca/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information)

Tamassee

10/10

Exceptional

(1 review)

"Fall weekend getaway and this was perfect location. Loved the back porch for coffee and views of the sun through all the colorful leaves. Felt like we were away from it all but just a short drive to restaurants, stores, lakes and parks!!!"

[](https://www.expedia.ca/Tamassee-Hotels-Forested-Tamassee-Escape-W-Screened-Porch.h93537127.Hotel-Information)

Cottage

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/2dac4e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/c3510f39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/ac5a37a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537102/3e065232.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Greenville Bungalow \~ 2 Mi to Downtown!

[](https://www.expedia.ca/Greenville-Hotels-Cozy-Greenville-Bungalow-2-Mi-To-Downtown.h93537102.Hotel-Information)

Greenville

8.0/10

Very good

(3 reviews)

"Amazing place. Great host. "

[](https://www.expedia.ca/Greenville-Hotels-Cozy-Greenville-Bungalow-2-Mi-To-Downtown.h93537102.Hotel-Information)

Cottage

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537126/08d5d5c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537126/d07ac743.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537126/71e6cec4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537126/c3bc809f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Home in Historic Area \~ 2 Mi to Main St!

[](https://www.expedia.ca/Greenville-Hotels-Cozy-Home-In-Historic-Area-2-Mi-To-Main-St.h93537126.Hotel-Information)

Greenville

10/10

Exceptional

(3 reviews)

"Absolutely adorable property. Little bit of an interesting part of town. We weren’t spending a bunch of time on property so it didn’t mater. Super close to down town and the house is well kept. "

[](https://www.expedia.ca/Greenville-Hotels-Cozy-Home-In-Historic-Area-2-Mi-To-Main-St.h93537126.Hotel-Information)

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## Stay near popular Southeastern United States attractions

!["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg)

### Clemson University

4.7/5 (738 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6127431)

![Exploring Falls Park on the Reedy in Downtown Greenville, South Carolina during a peaceful afternoon stroll with scenic views](https://images.trvl-media.com/place/6082697/4d276125-b8b6-4bd4-9887-c71157164970.jpg)

### Falls Park on the Reedy

4.7/5 (1,399 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6082697)

### Bon Secours Wellness Arena

4.2/5 (601 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6082715)

### Haywood Mall

4.3/5 (952 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6130785)

### Memorial Stadium

4.7/5 (201 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6193935)

### BMW Performance Center

4.7/5 (50 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses. 

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6217409)

## Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

[See all hotels in Upstate South Carolina](https://www.expedia.ca/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16&adults=2&regionId=6057939)

![Greenville - Spartanburg](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

Photo by Visit Greenville, South Carolina

## Top Upstate South Carolina Hotel Reviews

## Recent Reviews in Upstate South Carolina

![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg)

### Hyatt Place Greenville/Haywood

10/10 Excellent

"Great spot. The hot breakfast bar is a nice touch."

[](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg)

### Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent

"N/a"

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg)

### Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent

"The room was wonderful. The view amazing. The staff efficient and courteous. Loved the artwork throughout the hotel! "

[](https://expedia.ca/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information)

![Hotel Hartness](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/7f5c10e6_y.jpg)

### Hotel Hartness

10/10 Excellent

"I wish we had more time here. This was a short stay after we flew in and had to leave in the morning for a long drive. The hotel is stunning! There are trails around to hike and they offer bikes as well. The common areas and the room rooms are beautiful, comfortable, and very clean. Highly recommend!"

[](https://expedia.ca/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information)

![Hyatt Place Greenville Downtown](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/dac522c0_y.jpg)

### Hyatt Place Greenville Downtown

10/10 Excellent

"Great room. Very clean. Walking distance to dining, shops, and the concert we were in town to see."

[](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information)

![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg)

### Drury Inn & Suites Greenville

10/10 Excellent

"Excellent staff, clean room, enjoyed the breakfast and light dinner"

[](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205_y.jpg)

### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent

"We had a great at great price!"

[](https://expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information)

![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/8f34da45_y.jpg)

### The Shepherd Hotel Downtown Clemson

10/10 Excellent

"All was excellent"

[](https://expedia.ca/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information)

![Urban Boutique Hotel, BW Signature Collection](https://images.trvl-media.com/lodging/1000000/30000/24400/24334/f974826b_y.jpg)

### Urban Boutique Hotel, BW Signature Collection

10/10 Excellent

"clean room, breakfast, friendly staff, and quiet neighborhood"

[](https://expedia.ca/Greenville-Hotels-Urban-Boutique-Hotel.h24334.Hotel-Information)

## More cheap stays in Upstate South Carolina

![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/ce467f24_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC

CA $86

CA $95 total

Mar 3 - Mar 4

includes taxes & fees

7.8/10 Good! (1,004 reviews)

[](https://expedia.ca/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information)

![Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd](https://images.trvl-media.com/lodging/1000000/210000/202200/202137/b07dd898_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

1024 Woodruff Rd Greenville SC

CA $94

CA $103 total

Mar 15 - Mar 16

includes taxes & fees

8.2/10 Very Good! (1,004 reviews)

[](https://expedia.ca/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h202137.Hotel-Information)

![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

CA $113

CA $125 total

Mar 15 - Mar 16

includes taxes & fees

9.2/10 Wonderful! (1,442 reviews)

[](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information)

![Quality Inn Seneca Clemson Area US-123](https://images.trvl-media.com/lodging/1000000/80000/76800/76800/375f69b2_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Quality Inn Seneca Clemson Area US-123

226 Hi Tech Rd Seneca SC

CA $106

CA $125 total

Mar 6 - Mar 7

includes taxes & fees

8/10 Very Good! (681 reviews)

[](https://expedia.ca/Anderson-Hotels-Quality-Inn-Seneca-US-123.h76800.Hotel-Information)

![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3840h2557x0y4-16ef7416_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

CA $124

CA $138 total

Mar 5 - Mar 6

includes taxes & fees

8.2/10 Very Good! (1,006 reviews)

[](https://expedia.ca/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information)

![ECHO Suites Extended Stay by Wyndham Spartanburg](https://images.trvl-media.com/lodging/106000000/105490000/105488100/105488071/ab517c5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### ECHO Suites Extended Stay by Wyndham Spartanburg

490 W Blackstock Road Spartanburg SC

CA $128

CA $148 total

Mar 8 - Mar 9

includes taxes & fees

8.2/10 Very Good! (353 reviews)

[](https://expedia.ca/Spartanburg-Hotels-Echo-Suites-Spartanburg-Opening-June-2024.h105488071.Hotel-Information)

## Hotels in Upstate South Carolina with star rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg)

4 Star Hotels

11 properties

[](https://expedia.ca/4Star-Upstate-South-Carolina-Hotels.s40-0-d6057939.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg)

3 Star Hotels

194 properties

[](https://expedia.ca/3Star-Upstate-South-Carolina-Hotels.s30-0-d6057939.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg)

2 Star Hotels

316 properties

[](https://expedia.ca/2Star-Upstate-South-Carolina-Hotels.s20-0-d6057939.Travel-Guide-Filter-Hotels)

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