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Find hotels in Upstate South Carolina, SC from CA $89
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (749 reviews)
The price is CA $161
CA $181 total
includes taxes & fees
Jul 6 - Jul 7

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (511 reviews)
The price is CA $126
CA $137 total
includes taxes & fees
Jul 5 - Jul 6

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (236 reviews)
The price is CA $183
CA $201 total
includes taxes & fees
Jul 2 - Jul 3

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (469 reviews)
The price is CA $197
CA $214 total
includes taxes & fees
Jul 2 - Jul 3

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (854 reviews)
The price is CA $149
CA $163 total
includes taxes & fees
Jul 5 - Jul 6

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,281 reviews)
The price is CA $168
CA $185 total
includes taxes & fees
Jun 28 - Jun 29

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (867 reviews)
The price is CA $211
CA $234 total
includes taxes & fees
Jun 29 - Jun 30

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (809 reviews)
The price is CA $153
CA $172 total
includes taxes & fees
Jul 5 - Jul 6

Deluxe Inn
Deluxe InnMauldin
9.6 out of 10, Exceptional, (4 reviews)
The price is CA $81
CA $89 total
includes taxes & fees
Jun 23 - Jun 24

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,000 reviews)
The price is CA $197
CA $218 total
includes taxes & fees
Jul 1 - Jul 2

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (733 reviews)
The price is CA $118
CA $128 total
includes taxes & fees
Jun 28 - Jun 29

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (625 reviews)
The price is CA $156
CA $173 total
includes taxes & fees
Jul 3 - Jul 4

Four Points by Sheraton Spartanburg
Four Points by Sheraton SpartanburgSpartanburg
9.4 out of 10, Exceptional, (500 reviews)
The price is CA $168
CA $187 total
includes taxes & fees
Jun 28 - Jun 29

Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,515 reviews)
The price is CA $120
CA $132 total
includes taxes & fees
Jun 28 - Jun 29

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (924 reviews)
The price is CA $141
CA $156 total
includes taxes & fees
Jun 28 - Jun 29

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.4 out of 10, Very good, (1,004 reviews)
The price is CA $152
CA $168 total
includes taxes & fees
Jun 29 - Jun 30

AC Hotel by Marriott Spartanburg
AC Hotel by Marriott SpartanburgSpartanburg
9.4 out of 10, Exceptional, (636 reviews)
The price is CA $211
CA $234 total
includes taxes & fees
Jun 28 - Jun 29

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,002 reviews)
The price is CA $154
CA $192 total
includes taxes & fees
Jun 24 - Jun 25

Hilton Garden Inn Anderson
Hilton Garden Inn AndersonAnderson
9.0 out of 10, Wonderful, (739 reviews)
The price is CA $141
CA $156 total
includes taxes & fees
Jun 28 - Jun 29

SpringHill Suites by Marriott Greenville Downtown
SpringHill Suites by Marriott Greenville DowntownGreenville Downtown
9.6 out of 10, Exceptional, (1,003 reviews)
The price is CA $197
CA $216 total
includes taxes & fees
Jul 12 - Jul 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (80 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
More cheap stays in Upstate South Carolina

Urban Boutique Hotel, BW Signature Collection
536 Wade Hampton Blvd Greenville SC
The price is CA $91 per night from Jun 23 to Jun 24
CA $91
CA $100 total
Jun 23 - Jun 24
includes taxes & fees
8/10 Very Good! (1,003 reviews)
Hotels in Upstate South Carolina with star rating

4 Star Hotels
32 properties
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