Find hotels in Upstate South Carolina, SC from CA $80

Most hotels are fully refundable. Because flexibility matters.

Save an average of 15% on thousands of hotels with Expedia Rewards

Search over 2.9 million properties and 550 airlines worldwide

Check Upstate South Carolina hotel prices

Tonight
May 14 - May 15
Tomorrow night
May 15 - May 16
This weekend
May 17 - May 19
Next weekend
May 24 - May 26

Filter by

Popular filters
Popular filters
Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top 10 Upstate South Carolina hotels and places to stay

Superior Room, 2 Queen Beds
The Shepherd Hotel Downtown Clemson
4.0 star property
9.8 out of 10, Exceptional, (268)
"Very loud noise from bars across the road well into the night"
The price is CA $231
CA $256 total
includes taxes & fees
May 16 - May 17
The Shepherd Hotel Downtown Clemson
Classic Suite, 1 King Bed, Non Smoking, Kitchen (not pet friendly) | Terrace/patio
Black Bear Lodge of Sapphire
4.0 star property
9.8 out of 10, Exceptional, (172)
"Very pretty quiet property; fairly convenient to town. "
The price is CA $308
CA $344 total
includes taxes & fees
May 15 - May 16
Black Bear Lodge of Sapphire
Flat-screen TV
The Abernathy of Clemson
4.0 star property
9.6 out of 10, Exceptional, (391)
"Great bartender "
The price is CA $204
CA $226 total
includes taxes & fees
May 27 - May 28
The Abernathy of Clemson
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Indoor pool, outdoor pool
Hampton Inn Greer Greenville, SC
2.5 star property
9.6 out of 10, Exceptional, (221)
"Lovely location. Great stay. Breakfast had a variety of options from grits and oatmeal to muffins and waffles. "
The price is CA $190
CA $207 total
includes taxes & fees
Jun 1 - Jun 2
Hampton Inn Greer Greenville, SC
Property amenity
Cambria Hotel Greenville
3.0 star property
9.4 out of 10, Exceptional, (647)
"Great stay"
The price is CA $162
CA $178 total
includes taxes & fees
May 27 - May 28
Cambria Hotel Greenville
Indoor pool, outdoor pool
Drury Inn & Suites Greenville
3.0 star property
9.4 out of 10, Exceptional, (1000)
"Wonderful room, shower, breakfast- Great Value "
The price is CA $148
CA $162 total
includes taxes & fees
May 26 - May 27
Drury Inn & Suites Greenville
Meeting facility
Courtyard by Marriott Greenville Downtown
3.0 star property
9.4 out of 10, Exceptional, (841)
"Room was nice and clean, staff was friendly and helpful. "
The price is CA $217
CA $246 total
includes taxes & fees
May 26 - May 27
Courtyard by Marriott Greenville Downtown
Individually decorated, individually furnished, desk, laptop workspace
Comfort Suites Greenville Airport
2.5 star property
9.4 out of 10, Exceptional, (736)
"Wonderful personal greeting when we arrived! Hospitality was over the top!"
The price is CA $142
CA $156 total
includes taxes & fees
May 26 - May 27
Comfort Suites Greenville Airport
Exterior
Holiday Inn Express & Suites Greenville SE - Simpsonville, an IHG Hotel
2.5 star property
9.4 out of 10, Exceptional, (368)
"Employees were very friendly, all of them. Will definately stay here again"
The price is CA $189
CA $208 total
includes taxes & fees
May 20 - May 21
Holiday Inn Express & Suites Greenville SE - Simpsonville, an IHG Hotel
Exterior
Holiday Inn Express Brevard City Center, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (362)
"Beautiful "
The price is CA $164
CA $183 total
includes taxes & fees
Jun 9 - Jun 10
Holiday Inn Express Brevard City Center, an IHG Hotel
Lobby lounge
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
2.5 star property
9.2 out of 10, Wonderful, (423)
"Great manager"
The price is CA $159
CA $176 total
includes taxes & fees
Jun 2 - Jun 3
Holiday Inn Express Hotel & Suites Anderson-I-85, an IHG Hotel
The Clear View Cottage | Terrace/patio
Mountainaire Cottages & Inn
2.0 star property
9.2 out of 10, Wonderful, (14)
"Nice cottage and owner was nice and great"
The price is CA $197
CA $236 total
includes taxes & fees
May 15 - May 16
Mountainaire Cottages & Inn
Exterior
Hyatt Place Greenville/Downtown
3.0 star property
9.0 out of 10, Wonderful, (1016)
"Clean. Easy check-in. Convenient parking garage across the street. Walkable to downtown and Bon Secour Arena"
The price is CA $220
CA $249 total
includes taxes & fees
May 20 - May 21
Hyatt Place Greenville/Downtown
Exterior
Holiday Inn Express Hotel & Suites Greenville, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (780)
"Very nice with plenty of dining options in very close proximity. "
The price is CA $141
CA $158 total
includes taxes & fees
May 26 - May 27
Holiday Inn Express Hotel & Suites Greenville, an IHG Hotel
Exterior
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 star property
9.0 out of 10, Wonderful, (778)
"The staff is very friendly. Check in was fast and easy, room was clean with a big TV and nice air conditioning. The breakfast was organized and easy to access as well. Would definitely stay here again if I'm ever in the area."
The price is CA $163
CA $181 total
includes taxes & fees
May 19 - May 20
Holiday Inn Express & Suites Clemson, an IHG Hotel
Property entrance
Hyatt Regency Greenville
3.5 star property
8.8 out of 10, Excellent, (1000)
"Only issue was when I called for airport to hotel shuttle service they said there was none. Should be taken off amenities list."
The price is CA $220
CA $248 total
includes taxes & fees
May 26 - May 27
Hyatt Regency Greenville
Exterior
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
2.5 star property
8.6 out of 10, Excellent, (1000)
"Great place. Friendly staff. "
The price is CA $174
CA $191 total
includes taxes & fees
May 26 - May 27
Holiday Inn Express & Suites Greenville - Downtown, an IHG Hotel
Lobby
Best Western Seneca-Clemson
2.5 star property
8.4 out of 10, Very good, (519)
"I was very impressed with the friendliness of the desk clerk. "
The price is CA $135
CA $148 total
includes taxes & fees
Jun 13 - Jun 14
Best Western Seneca-Clemson
Lobby
Comfort Suites At WestGate Mall
2.5 star property
8.2 out of 10, Very good, (1000)
"Very accommodating if you have dogs. Which with so many people traveling with pets it is very appreciated. Thank you"
The price is CA $127
CA $141 total
includes taxes & fees
Jun 2 - Jun 3
Comfort Suites At WestGate Mall
Exterior
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
2.5 star property
8.0 out of 10, Very good, (700)
"Excellent Stay and Service! "
The price is CA $155
CA $171 total
includes taxes & fees
May 18 - May 19
Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
Don't see what you're looking for?
See all available properties in Upstate South Carolina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.