A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

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Our top choices for Upstate South Carolina vacation rentals

1. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (873 reviews)
"We had a great time, very close to eating and shopping. The amenities were very helpful and we felt the area was very safe. We had an issue with getting a ticket even though we paid for parking but it was taken care of within an hour!"
United States
Robin
The price is CA $139
CA $157 total
includes taxes & fees
Sep 1 - Sep 2
Mint House Greenville Downtown by Kasa

2. 1 Queen Bed | Non-Smoking, Micfridge

1 Queen Bed | Non-Smoking, Micfridge
Greenville SC
9.8 out of 10, Exceptional, (49 reviews)
The price is CA $91
CA $100 total
includes taxes & fees
Aug 13 - Aug 14
1 Queen Bed | Non-Smoking, Micfridge

3. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (103 reviews)
"Very cute house and very clean. The pictures are accurate. The neighborhood is quiet and we felt safe during our entire stay. The host are very responsive. We would stay here again! "
United States
Clarissa B.
The price is CA $102
CA $310 total
includes taxes & fees
Aug 23 - Aug 24
The Blue Bungalow by Unity Park - Newly Renovated

4. Cozy 1BR Close to Downtown & Greenville Drive Baseball

Cozy 1BR Close to Downtown & Greenville Drive Baseball
Greenville
9.2 out of 10, Wonderful, (31 reviews)
"Was a very nice place to stay. I would stay there again. Thank you for the clean place."
United States
Darwin N.
The price is CA $77
CA $245 total
includes taxes & fees
Aug 18 - Aug 19
Cozy 1BR Close to Downtown & Greenville Drive Baseball

5. 2BR 2Bath - Swamp Rabbit Trail Resort

2BR 2Bath - Swamp Rabbit Trail Resort
Greenville
9.2 out of 10, Wonderful, (40 reviews)
"Super clean and the king bed was so comfortable. "
United States
Anonymous traveller
The price is CA $94
CA $266 total
includes taxes & fees
Aug 14 - Aug 15
2BR 2Bath - Swamp Rabbit Trail Resort

6. Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville
Greenville
9.4 out of 10, Exceptional, (15 reviews)
"Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! "
United States
David R.
The price is CA $121
CA $225 total
includes taxes & fees
Aug 12 - Aug 13
Historic 19th Century Cabin in Greenville

7. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.4 out of 10, Exceptional, (36 reviews)
"We had a great stay- the location was close to everything & very clean "
United States
Anonymous traveller
The price is CA $78
CA $247 total
includes taxes & fees
Aug 16 - Aug 17
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

8. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
Greenville
10.0 out of 10, Exceptional, (13 reviews)
"I was provided everything I needed."
United States
Pat
The price is CA $126
CA $230 total
includes taxes & fees
Aug 30 - Aug 31
Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

9. Bright & Cozy 2BR Apt w/ Parking

Bright & Cozy 2BR Apt w/ Parking
Greenville
9.8 out of 10, Exceptional, (10 reviews)
The price is CA $128
CA $338 total
includes taxes & fees
Aug 11 - Aug 12
Bright & Cozy 2BR Apt w/ Parking

10. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (95 reviews)
"It was a good getaway trip"
United States
laysha
The price is CA $138
CA $213 total
includes taxes & fees
Aug 17 - Aug 18
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

11. Beautiful Home Close To Everything

Beautiful Home Close To Everything
Greenville
9.6 out of 10, Exceptional, (181 reviews)
"Great place for us with 4 guys going to the basketball games in town. Plenty of room. It is on a busy street, but the road noise was not an issue. Enjoyable stay."
United States
Leo P.
The price is CA $156
CA $433 total
includes taxes & fees
Aug 11 - Aug 12
Beautiful Home Close To Everything

12. Riverwalk Falls-lovely one bedroom condo

Riverwalk Falls-lovely one bedroom condo
Greenville Downtown
10.0 out of 10, Exceptional, (191 reviews)
"Parking is close. The place is clean and comfortable. "
United States
Michael K.
The price is CA $217
CA $389 total
includes taxes & fees
Aug 11 - Aug 12
Riverwalk Falls-lovely one bedroom condo

13. GORGEOUS 1 BR on MAIN #2

GORGEOUS 1 BR on MAIN #2
Greenville Downtown
9.8 out of 10, Exceptional, (26 reviews)
The price is CA $161
CA $323 total
includes taxes & fees
Aug 11 - Aug 12
GORGEOUS 1 BR on MAIN #2

14. Urban Escape: Industrial 2BR/2BA

Urban Escape: Industrial 2BR/2BA
Greenville
9.0 out of 10, Wonderful, (22 reviews)
"Clean, communicative owner and easy access to downtown - highly recommend. "
United States
Stephen C.
The price is CA $135
CA $365 total
includes taxes & fees
Sep 1 - Sep 2
Urban Escape: Industrial 2BR/2BA

15. Adorable Upscale cottage in Downtown Fountain Inn.

Adorable Upscale cottage in Downtown Fountain Inn.
Fountain Inn
10.0 out of 10, Exceptional, (44 reviews)
"Really beautiful place, loved that it was dog friendly."
United States
Pam C.
The price is CA $160
CA $348 total
includes taxes & fees
Aug 11 - Aug 12
Adorable Upscale cottage in Downtown Fountain Inn.

16. Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!

Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!
Greenville Downtown
9.2 out of 10, Wonderful, (90 reviews)
"Perfect location. Super clean, open concept. Great parking options."
United States
Sarah P.
The price is CA $209
CA $500 total
includes taxes & fees
Aug 11 - Aug 12
Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!

17. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is CA $229
CA $370 total
includes taxes & fees
Aug 11 - Aug 12
Carolina Camp Cedar

18. Unique, Historic 2BD Apt w/ Study

Unique, Historic 2BD Apt w/ Study
Greenville
The price is CA $151
CA $368 total
includes taxes & fees
Aug 11 - Aug 12
Unique, Historic 2BD Apt w/ Study

19. 1 Queen Studio w/ Full Kitchen | Breakfast + Pool

1 Queen Studio w/ Full Kitchen | Breakfast + Pool
Greenville
The price is CA $222
CA $278 total
includes taxes & fees
Aug 23 - Aug 24
1 Queen Studio w/ Full Kitchen | Breakfast + Pool

20. Downtown Condo Steps to Main Street

Downtown Condo Steps to Main Street
Greenville Downtown
10.0 out of 10, Exceptional, (25 reviews)
"Great location...lots of entertainment mere steps away"
United States
Larry W.
The price is CA $180
CA $354 total
includes taxes & fees
Aug 12 - Aug 13
Downtown Condo Steps to Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Upstate South Carolina. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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