Upstate South Carolina Vacation Rentals
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Upstate South Carolina vacation rentals
2. The Blue Bungalow by Unity Park - Newly Renovated
The Blue Bungalow by Unity Park - Newly Renovated
3. Walk to Bridgeway Station! Home w/ Pool Access
Walk to Bridgeway Station! Home w/ Pool Access
4. Modern Condo in the Heart of Downtown Greenville
Modern Condo in the Heart of Downtown Greenville
5. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
6. 2 Queen Beds Non-Smoking
2 Queen Beds Non-Smoking
8. Bright & Cozy 2BR Apt w/ Parking
Bright & Cozy 2BR Apt w/ Parking
Find vacation rentals that suit your style
Top Upstate South Carolina Hotel Reviews
Best Western Plus Greenville I-385 Inn & Suites
Find out more about Upstate South Carolina
Everything you need to know about Upstate South Carolina vacation rentals
Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!
There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.
Upstate South Carolina vacation rentals: An excellent choice for every season
Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .
Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Upstate South Carolina vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. The selection of Upstate South Carolina vacation rentals we have selected for you start as low as CA $167 per night. Entering your travel dates in the search wizard you might find even better deals!
How to find incredible deals on Upstate South Carolina rentals
At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.
To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.
If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.
Explore a world of travel with Expedia
- Greenville Downtown Hotels
- Hotels near Centre Stage
- B&B in Greenville
- Beach Hotel Hotels in Greenville
- Hotels with Free Airport Shuttle in Greenville
- Ac Hotel By Marriott Greenville
- Greenville Hotels
- Motels in Greenville
- Mint House Greenville Downtown by Kasa
- Apartments in Greenville
- Farmstay in Greenville
- Five Forks Hotels
- 2 Bed near Greenville
- 5 Star Hotels in Greenville
- Safari Tentalow in Greenville
- Hotels near Christ Episcopal Church
- Hotels near Bon Secours Wellness Arena
- Cabin Rentals in Greenville - Spartanburg
- Adults Only Resorts & in Greenville
- Hotels with Free Breakfast in Greenville
- Hotel Wedding Venues Hotels in Woodside Cotton Mill Village Historic District
- Spa Hotels in Upstate South Carolina
- All Inclusive Resorts and in Greenville
- Simpsonville Hotels
- 2br Cedar Lane Road Retreat at Swamp Rabbit Trail!
- Accor Hotels in Greenville
- Bright Greenville Apt w/ Balcony
- Cabin Rentals in Greenville
- 3 Star Hotels in Greenville
- Luxe Mountain getaway only 15 minutes from the city!
- Cozy Hub~Comfortable Simpsonville Home ~Long-Term Stays Welcome ~Community Pool
- Tru by Hilton Greenville Woodruff Road
- 24 Riverview Dr
- 4 Star Hotels in West End
- Hotels with Free Airport Shuttle in Greenville - Spartanburg
- Hotel Wedding Venues Hotels in Colonel Elias Earle Historic District
- Judson Mill Lofts with all the amenities
- Golf Hotels in Greenville - Spartanburg
- Flights from Toronto (YYZ) to Greenville (GMU)
- Flights from Orlando (MCO) to Greenville (GDC)
- Flights from Atlanta (ATL) to Greenville (GSP)
- Flights from Annapolis (ANP) to Greenville (GMU)
- Flights from San Diego (SAN) to Greenville (GMU)
- Flights from Bangor (BGR) to Greenville (GSP)
- Flights from West Palm Beach (PBI) to Greenville (GMU)
- Flights from Ottawa (YOW) to Greenville (GSP)
- Flights from Calgary (YYC) to Greenville (GSP)
- Flights from Manteo (MEO) to Greenville (GMU)
- Flights from Raleigh (RDU) to Greenville (GDC)
- Flights to Greenville - Spartanburg
- Flights from Detroit (DTW) to Greenville (GDC)
- Flights from Rome (FCO) to Greenville (GDC)
- Flights from Schenectady (SCH) to Greenville (GMU)
- Flights from Greenville
- Flights from New York (JFK) to Greenville (GMU)
- Flights from Vancouver (YVR) to Greenville (GSP)
- Flights from Birmingham (BHM) to Greenville (GMU)
- Flights to Simpsonville
- Flights from Vancouver (YVR) to Greenville (GMU)
- Flights from Detroit (DTW) to Greenville (GSP)
- Flights to Greenville
- Flights from Philadelphia (PHL) to Greenville (GMU)
- Flights from Montreal (YUL) to Greenville (GSP)
- Flights from Anderson (AND) to Greenville (GDC)
- Flights from Des Moines (DSM) to Greenville (GDC)
- Flights from Donaldson Center
- Flights from Buffalo (BUF) to Greenville (GSP)
- Flights from Montreal (YUL) to Greenville (GMU)
- Flights from Washington (DCA) to Greenville (GDC)
- Flights from Greenville-Spartanburg Intl.
- Flights from Toronto (YYZ) to Greenville (GSP)
- Flights from Greenville - Spartanburg
- Flights from Miami (MIA) to Greenville (GDC)
- Enterprise Rental Cars in Greenville
- Drive on Holidays Rental Cars in Greenville - Spartanburg
- Avis Rental Cars in Greenville
- Europcar Rental Cars in Greenville
- Enterprise Rental Cars in Greenville Downtown
- Ace Rental Cars in Greenville Downtown
- Wiber Rental Cars in Greenville
- Car rental Greenville
- Car rental Simpsonville
- Routes Rental Cars in Greenville - Spartanburg
- Car rentals near Prisma Health Greenville Memorial Hospital
- Rental cars Greenville-Spartanburg Intl. airport
