Title: Mountain Vacations in Upstate South Carolina 2026 | Expedia.ca ![](https://images.trvl-media.com/place/144669/e945b35d-16b4-408c-818b-68622e164446.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Upstate South Carolina Mountain Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by RVLuckyorWhat - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Mountain Hotels in Upstate South Carolina ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites Greenville 10 Carolina Point Pkwy Greenville SC - 2 hours drive from Clemson University Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ... 9.6/10 Exceptional! (1,005 reviews) Hot tub was hot and clean, breakfast and super were delicious, friendly staff Reviewed on Mar 30, 2026 [](https://expedia.ca/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Westin Poinsett Greenville 120 South Main St Greenville SC - 1 hour drive from Clemson University Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ... 9.2/10 Wonderful! (1,001 reviews) Valet parking was much easier but significantly more expensive. Reviewed on Mar 20, 2026 [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Hampton Inn Gaffney](https://images.trvl-media.com/lodging/1000000/430000/424900/424882/cd259adf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Gaffney 115 Nancy Creek Rd Gaffney SC - 3 hours drive from Clemson University Stay at this hotel in Gaffney. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Gaffney ... 8.8/10 Excellent! (695 reviews) The room was nice size and the bed was comfortable. The shower and bathroom were nice as well. Reviewed on Mar 22, 2026 [](https://expedia.ca/Gaffney-Hotels-Hampton-Inn-Gaffney.h424882.Hotel-Information) [See all 2,949 properties in Upstate South Carolina](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6057939) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Upstate South Carolina ](https://expedia.ca/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[ Upstate South Carolina Hotels ](https://expedia.ca/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[ Upstate South Carolina Vacation Rentals ](https://expedia.ca/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[ Upstate South Carolina Car Rentals ](https://expedia.ca/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide)[ Upstate South Carolina Vacations ](https://expedia.ca/Upstate-South-Carolina.d6057939.Destination-Travel-Guides)[ Things to do in Upstate South Carolina ](https://expedia.ca/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app