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Mountain Hotels in Upstate South Carolina

Drury Inn & Suites Greenville

10 Carolina Point Pkwy Greenville SC

2 hours drive from Clemson University

Book a stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

9.6/10 Exceptional! (1,022 reviews)

"Drury does a great job w/ amenities, staff and cleaning. Only minor issues nothing to report."

Reviewed on Jun 26, 2026

The Westin Poinsett Greenville

120 South Main St Greenville SC

1 hour drive from Clemson University

Book a stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle, and 24-hour room service. Our guests praise the ...

9.4/10 Exceptional! (1,000 reviews)

"Always our go to place to stay in Greenville,SC. Never disappointed"

Reviewed on Jun 14, 2026

Hampton Inn Gaffney

115 Nancy Creek Rd Gaffney SC

3 hours drive from Clemson University

Stay at this hotel in Gaffney. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Gaffney ...

8.8/10 Excellent! (735 reviews)

"excellent breakfast friendly staff"

Reviewed on Jun 27, 2026

See all 3,017 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.