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Adults Only Hotels in Northeast Missouri

Historic Iron Horse Inn

207 E. 4th Street Hermann MO

2 hours drive from St. Louis Union Station

Stay at this B&B in Hermann. Enjoy free breakfast, free parking, and a garden. Popular attractions Hermannhof Vineyards and Deutschheim State Historic Site are ...

8.4/10 Very Good! (21 reviews)

The inn keeper was fabulous. The rooms were clean and cozy. Will defiantly be back.

Reviewed on Oct 30, 2023

Moonrise Hotel

6177 Delmar Blvd St. Louis MO

10 min drive from St. Louis Union Station

Book a stay at this boutique hotel in St. Louis. Enjoy free WiFi, free parking, and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in ...

9/10 Wonderful! (1,921 reviews)

It's in an excellent location. Parking information was confusing. For the price paid, I thought it would be nicer.

Reviewed on Apr 11, 2026

See all 2,924 properties in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.