
Popular airlines from San Diego Intl. Airport (SAN) to Lambert-St. Louis International Airport (STL)
- Alaska Airlines
Alaska Airlines
- United
United
- American Airlines
American Airlines
- Delta
Delta
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Hawaiian Airlines
Hawaiian Airlines
- Plan, book, fly with confidence
trending down icon Be in the knowGet alerts if flight prices drop or rise*bex rewards loyalty icon Book smarterSave up to 30% on select hotels after you book a flight*payments icon
Cheap flights from San Diego (SAN) to St. Louis (STL)
Prices were available within the past 7 days and start at CA $156 for one-way flights and CA $383 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from San Diego (SAN) to St. Louis (STL)
October is typically the cheapest month to fly
Graph displaying average flight prices per month
Origin airport | San Diego Intl. |
Destination airport | Lambert-St. Louis Intl. |
Roundtrip price | CA $383 |
Distance | 2487 km |
Average flight time | 5 hours 58 mins |
San Diego to St. Louis Flights
The easy way to book your flights from San Diego to St. Louis
With Expedia, it’s simple to find and book flights to St. Louis from San Diego whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Lambert-St. Louis Intl., too.
Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from San Diego to St. Louis today, tomorrow, or this week.
Save dollars with cheap flights from San Diego Intl., SAN to Lambert-St. Louis Intl., STL
Sort your search results by price to find great deals on your flight from San Diego to St. Louis—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to St. Louis from San Diego currently is just CA $383 rising to CA $452.
Here are more money-saving tips:
- Fly in October when flight prices are normally at their lowest
- Book about a month to 6 weeks before you travel for the best prices to St. Louis
- Avoid peak season and weekends when flights can cost more
- Early morning and late-night flights are sometimes cheaper, so try varying your travel times
- One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!
Reasons to choose Expedia for your flight to St. Louis from San Diego
Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to St. Louis with Expedia today.
Frequently asked questions
Explore a world of travel with Expedia
- Trending Routes
- Trending Flights
- Top Flights Destinations
- Other Airlines
- Cheap Flights from Other Airports
- Expedia's Latest Trends
Top Routes from San Diego
- San Diego to Mexico City (SAN - MEX)
- San Diego to Newark Liberty Intl. Airport (SAN - EWR)
- San Diego to Calgary (SAN - YYC)
- San Diego to Honolulu (SAN - HNL)
- San Diego to New York (SAN - LGA)
- San Diego to El Paso (SAN - ELP)
- San Diego to Manila (SAN - MNL)
- San Diego to Seattle (SAN - SEA)
- San Diego to New York (SAN - JFK)
- San Diego to Montreal (SAN - YUL)
- San Diego to Vancouver (SAN - YVR)
- San Diego to Abbotsford (SAN - YXX)
Top Routes to St. Louis
- Ottawa to St. Louis (YOW - STL)
- Newark Liberty Intl. Airport to St. Louis (EWR - STL)
- Calgary to St. Louis (YYC - STL)
- Kelowna to St. Louis (YLW - STL)
- Burlington to St. Louis (BTV - STL)
- Detroit to St. Louis (DTW - STL)
- New York to St. Louis (LGA - STL)
- Winnipeg to St. Louis (YWG - STL)
- Seattle to St. Louis (SEA - STL)
- Montreal to St. Louis (YUL - STL)
- Saint John to St. Louis (YSJ - STL)
- Buffalo to St. Louis (BUF - STL)
Top Routes from San Diego
Top Flight Destinations
- Flights to Las Vegas
- Flights to New York
- Flights to Orlando
- Flights to Chicago
- Flights to Myrtle Beach
- Flights to San Diego
- Flights to Panama City Beach
- Flights to Destin
- Flights to Los Angeles
- Flights to Ocean City
- Flights to Miami
- Flights to Boston
- Flights to Nashville
- Flights to Atlantic City
- Flights to Pigeon Forge
- Flights to Atlanta
- Flights to San Francisco
- Flights to Virginia Beach
- Flights to Gulf Shores
- Flights to Seattle
Expedia's Latest Trends
- Flights from Ottawa to Las Vegas
- Flights from Vancouver to San Diego
- Flights from Vancouver to Las Vegas
- Flights from Toronto to Philadelphia
- Flights from Edmonton to Los Angeles
- Flights from Toronto to Seattle
- Flights from Toronto to San Diego
- Flights from Toronto to Myrtle Beach
- Flights from Toronto to New York
- Flights from Montreal to Las Vegas
- Flights from Detroit to Las Vegas
- Flights from Vancouver to Seattle
- Flights from Calgary to Los Angeles
- Flights from Montreal to Fort Lauderdale
- Flights from Winnipeg to Las Vegas
- Flights from Montreal to Los Angeles
- Flights from Winnipeg to Los Angeles
- Flights from Calgary to Seattle
- Flights from Los Angeles to Toronto
- Flights from Buffalo to Fort Lauderdale
- Flights from Toronto to Fort Lauderdale
- Flights from Calgary to San Francisco
- Flights from Bellingham to Las Vegas
- Flights from Seattle to Delhi
- Flights from Vancouver to Palm Springs
- Flights from Vancouver to Los Angeles
- Flights from Vancouver to Dallas
- Flights from Toronto to Las Vegas
- Flights from Toronto to Los Angeles
- Flights from Edmonton to Seattle