Title: Book The Best Hotels in Louisiana, MO for 2026 from CA $86 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Louisiana](https://expedia.ca/Louisiana-Vacation-Rentals.d127811.Travel-Guide-VacationRentals)[Flights to Louisiana](https://expedia.ca/Cheap-Flights-To-Louisiana.d127811.Travel-Guide-Flights)[Louisiana Car Rentals](https://expedia.ca/Car-Rentals-In-Louisiana.d127811.Car-Rental-Guide)[Louisiana Vacation Packages](https://expedia.ca/Louisiana.d127811.Destination-Travel-Guides) ![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Louisiana Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=PETS) Pool [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&amenities=HOT_TUB) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Louisiana%2C+Missouri%2C+United+States+of+America®ionId=127811&latLong=39.448937%2C-91.051529&adults=2&startDate=2026-04-07&d1=2026-04-07&endDate=2026-04-09&d2=2026-04-09&travelerType=family_friendly) ## Check prices for these dates Tonight [Mar 23 - Mar 24](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2026-03-23&endDate=2026-03-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 24 - Mar 25](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2026-03-24&endDate=2026-03-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Louisiana hotels ![Property grounds](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/2cb4a716.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/e95aba72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/0bee3acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12240000/12232200/12232142/5cf5de0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River's Edge Motel [](https://www.expedia.ca/Hannibal-Hotels-Rivers-Edge-Motel.h12232142.Hotel-Information) Louisiana 9.0/10 Wonderful (361 reviews) "Staff was really nice and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) rhonda CA $110 CA $125 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Hannibal-Hotels-Rivers-Edge-Motel.h12232142.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/9536012a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/50983b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/2c8ee78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/be738395.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Eagles Nest Inn [](https://www.expedia.ca/Louisiana-Hotels-The-Eagles-Nest-Inn.h111944656.Hotel-Information) Louisiana 9.4/10 Exceptional (22 reviews) "Best place to stay in town!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $131 CA $149 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Louisiana-Hotels-The-Eagles-Nest-Inn.h111944656.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/73b1969e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, rollaway beds](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/79af7d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/12a7ffe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Hannibal West [](https://www.expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) Hannibal 8.0/10 Very good (1,006 reviews) "Excellent hotel with great bathroom amenities and an excellent breakfast. Our traveling companion said the biscuits and gravy were the best she'd ever had. Highly recommend this hotel and the included breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy CA $106 CA $123 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/84f5eec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/68a74acd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/087ffe43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/w2980h2000x0y0-33592151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Super-8-By-Wyndham-Hannibal.h459674.Hotel-Information) Hannibal 7.2/10 Good (1,002 reviews) "Clean rooms, easy check in, friendly staff, awesome location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda CA $85 CA $97 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Hannibal-Hotels-Super-8-By-Wyndham-Hannibal.h459674.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f348d54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/42aa710b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/11865b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/a2d8a404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Hannibal, MO [](https://www.expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) Hannibal 7.4/10 Good (1,002 reviews) "Great stay with no issues at all." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Thomas CA $77 CA $88 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/f63d6bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/f01081f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/5c0eb04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Hannibal West [](https://www.expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) Hannibal 9.6/10 Exceptional (1,004 reviews) "Would highly recommend to anyone needed an excellent hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $150 CA $174 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/946d8e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/1af516fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/baf4a218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17050000/17047300/17047233/b4ce7d70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Monroe Street Suites [](https://www.expedia.ca/Pittsfield-Hotels-Monroe-Street-Suites.h17047233.Hotel-Information) Pittsfield 9.6/10 Exceptional (59 reviews) "A unique luxurious find for rest and respite on a long trip home. Would stay here again, without any hesitation!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Donna CA $134 CA $148 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Pittsfield-Hotels-Monroe-Street-Suites.h17047233.Hotel-Information) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/3aa4b816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/dcca73dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/87b01476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/a188d547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites - Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) Hannibal 7.6/10 Good (679 reviews) "The front desk woman was so helpful and kind. The location was extremely clean, the breakfast was honestly one of the best I have had for a free continental breakfast, and I loved the hot tub. I felt very safe. Beds were comfortable. Great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kayleigh CA $121 CA $143 total includes taxes & fees Apr 19 - Apr 20 [](https://www.expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![Breakfast meal](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/6afc32c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/080807c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Ensuite (King Suite)](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/80a90a0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/7000000/6660000/6659600/6659525/b7c49e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### William Watson Hotel [](https://www.expedia.ca/Pittsfield-Hotels-William-Watson-Hotel.h6659525.Hotel-Information) Pittsfield 9.2/10 Wonderful (348 reviews) "Great location, restaurant downstairs, friendly staff, microwaves and refrigerator in room, historic significance " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Druann CA $108 CA $119 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Pittsfield-Hotels-William-Watson-Hotel.h6659525.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6002c086.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/f58df419.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/067469c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6abc4a97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson BY Wyndham Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) Hannibal 7.2/10 Good (158 reviews) "Truth is that this place was a great value. The rooms and inside were very clean and the staff was excellent. Value for price is exceptional. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $78 CA $90 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/a819ab14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/27dc5b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast for a fee](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/w1752h1169x5y3-37bf337e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/13000/12968/83466281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Days-Inn-By-Wyndham-Hannibal.h12968.Hotel-Information) Hannibal 7.4/10 Good (227 reviews) "The room was clean. The staff were courteous. Breakfast was poor. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helen CA $87 CA $100 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Hannibal-Hotels-Days-Inn-By-Wyndham-Hannibal.h12968.Hotel-Information) ![Desk, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/74fd9989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/b520e740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/721fce3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western On The River [](https://www.expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) Hannibal 8.6/10 Excellent (1,011 reviews) "Tony did a great job at front desk answering all our questions about the room and Hannibal." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steven CA $139 CA $159 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/87b66cdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/a47c0b8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/6dfa4459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/10000000/9990000/9986700/9986625/86469d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Green Acres Hotel [](https://www.expedia.ca/Pittsfield-Hotels-Green-Acres-Hotel.h9986625.Hotel-Information) Pittsfield 8.6/10 Excellent (143 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeramy CA $175 CA $193 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Pittsfield-Hotels-Green-Acres-Hotel.h9986625.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/cc28712b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/df66a518.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/d2c89a48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/ad87f56f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) Hannibal 6.4/10 (746 reviews) "It was ok as a hotel stay for over night, even tho baymont took it over, it isnt any better. The owner i think lives there, there wasnt any towels in our room. I didnt get a friendly vibe from them at all. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $86 CA $100 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/0aa674c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/e9aab2d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/e6a3a05e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5640000/5637500/5637460/74c9995c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Pittsfield [](https://www.expedia.ca/Pittsfield-Hotels-Rodeway-Inn.h5637460.Hotel-Information) Pittsfield 6.8/10 (130 reviews) "Great little hotel, perfect for an overnight pit stop " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $78 CA $86 total includes taxes & fees Apr 5 - Apr 6 [](https://www.expedia.ca/Pittsfield-Hotels-Rodeway-Inn.h5637460.Hotel-Information) ![Honeymoon Room, River View](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/460bcf0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Studio Suite | Private kitchen](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/3d6685cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/39c331f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Room, River View | Living room](https://images.trvl-media.com/lodging/38000000/37180000/37171800/37171765/158a8120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverside Inn Hannibal [](https://www.expedia.ca/Hannibal-Hotels-Riverside-Inn.h37171765.Hotel-Information) Hannibal 9.4/10 Exceptional (170 reviews) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandy CA $195 CA $272 total includes taxes & fees Mar 28 - Mar 29 [](https://www.expedia.ca/Hannibal-Hotels-Riverside-Inn.h37171765.Hotel-Information) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/dca4ff6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/6ad6820a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/0f6bae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/104000000/103850000/103844400/103844330/88cd794c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garden House Bed and Breakfast [](https://www.expedia.ca/Hannibal-Hotels-Garden-House-Bed-And-Breakfast.h103844330.Hotel-Information) Hannibal 8.4/10 Very good (40 reviews) "Great location. Clean rooms, Staff very friendly." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles CA $132 CA $152 total includes taxes & fees Apr 12 - Apr 13 [](https://www.expedia.ca/Hannibal-Hotels-Garden-House-Bed-And-Breakfast.h103844330.Hotel-Information) ![Down comforters, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/0ce65e62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/d6514417.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Living area](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/1abb1816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/4063c21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lighthouse Inn & Suites [](https://www.expedia.ca/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) Hannibal 8.8/10 Excellent (25 reviews) "Very nice room, close enough to walk to riverfront attractions. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $232 CA $313 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=127811&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLouisiana-Hotels.d127811.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLouisiana-Hotels.d127811.Travel-Guide-Hotels) ## Learn more about Louisiana Like rivers? Get away to relaxing Louisiana! [See all hotels in Louisiana](https://www.expedia.ca/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&adults=2®ionId=127811) ![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=900&h=569&p=1&q=high) ## Top Louisiana Hotel Reviews ## Recent Reviews in Louisiana ![Sleep Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254_y.jpg) ### Sleep Inn & Suites Hannibal West 10/10 Excellent "Clean and comfortable room. Lots of options for hot breakfast." [](https://expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ![Best Western On The River](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71_y.jpg) ### Best Western On The River 8/10 Good "This was an amazing overall stay, we loved that it was within walking distance of everything we wanted access to. The pool is in the main lobby of the hotel which was interesting but no big deal. We did purchase some drinks from the gift shop area and paid with our card and almost got charged again for them through our room which we believe was an honest mistake just make sure you're double checking. My biggest complaint of the hotel was the parking lot lights that shined right into our room and the only option to block them out were black out curtains. We can't do black out curtains otherwise we'll sleep in too long. If you can do black out curtains then great, it won't be a big deal for you. " [](https://expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Quality Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3_y.jpg) ### Quality Inn & Suites Hannibal West 10/10 Excellent "No question the nicest motel in the price range that we paid. Breakfast was better than any other motel that we’ve previously stayed in that price range. And the motel was much nicer." [](https://expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Super 8 by Wyndham Hannibal](https://images.trvl-media.com/lodging/1000000/460000/459700/459674/84f5eec7_y.jpg) ### Super 8 by Wyndham Hannibal 10/10 Excellent "Very clean with friendly staff and a very reasonable price. We’ve spent a lot more on hotels that didn’t come close to this one in cleanliness. Will definitely stay here again if we are ever in the area. " [](https://expedia.ca/Hannibal-Hotels-Super-8-By-Wyndham-Hannibal.h459674.Hotel-Information) ![Howard Johnson BY Wyndham Hannibal](https://images.trvl-media.com/lodging/77000000/76270000/76266600/76266570/6002c086_y.jpg) ### Howard Johnson BY Wyndham Hannibal 10/10 Excellent "Awesome" [](https://expedia.ca/Hannibal-Hotels-Howard-Johnson-BY-Wyndham-Hannibal.h76266570.Hotel-Information) ![The Yellow Rose Historic Home](https://images.trvl-media.com/lodging/96000000/95980000/95977000/95976949/a0b541f4_y.jpg) ### The Yellow Rose Historic Home 10/10 Excellent "Everything was great!" [](https://expedia.ca/Louisiana-Hotels-The-Yellow-Rose-Historic-Home.h95976949.Hotel-Information) ![Baymont by Wyndham Hannibal](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/cc28712b_y.jpg) ### Baymont by Wyndham Hannibal 10/10 Excellent "Great" [](https://expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![The Eagles Nest Inn](https://images.trvl-media.com/lodging/112000000/111950000/111944700/111944656/9536012a_y.jpg) ### The Eagles Nest Inn 10/10 Excellent "Best place to stay in town!" [](https://expedia.ca/Louisiana-Hotels-The-Eagles-Nest-Inn.h111944656.Hotel-Information) ![Motel 6 Hannibal, MO](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f348d54f_y.jpg) ### Motel 6 Hannibal, MO 10/10 Excellent "Basic motel that had super clean rooms with very nice beds. It suited our needs for a one night stay while in town for a convention. Would highly recommend for "no frills" place to stay in Hannibal at a great price." [](https://expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ## More cheap stays in Louisiana ![Motel 6 Hannibal, MO](https://images.trvl-media.com/lodging/1000000/30000/28400/28323/f348d54f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Hannibal, MO 123 Huckleberry Heights Dr Hannibal MO CA $77 CA $88 total Mar 25 - Mar 26 includes taxes & fees 7.4/10 Good! (1,002 reviews) [](https://expedia.ca/Hannibal-Hotels-Motel-6-Hannibal.h28323.Hotel-Information) ![Baymont by Wyndham Hannibal](https://images.trvl-media.com/lodging/4000000/3800000/3790200/3790159/cc28712b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baymont by Wyndham Hannibal 4141 Market St Hannibal MO CA $86 CA $100 total Mar 26 - Mar 27 includes taxes & fees 6.4/10 (746 reviews) [](https://expedia.ca/Hannibal-Hotels-Hannibal-Inn.h3790159.Hotel-Information) ![Quality Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/1000000/990000/983700/983646/4e0fe2c3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn & Suites Hannibal West 120 Lindsey Drive Hannibal MO CA $106 CA $123 total Apr 12 - Apr 13 includes taxes & fees 8/10 Very Good! (1,006 reviews) [](https://expedia.ca/Hannibal-Hotels-Quality-Inn-Suites-Hannibal.h983646.Hotel-Information) ![Comfort Inn & Suites - Hannibal](https://images.trvl-media.com/lodging/1000000/70000/64300/64231/3aa4b816_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Inn & Suites - Hannibal 4000 Market St Hannibal MO CA $121 CA $143 total Apr 19 - Apr 20 includes taxes & fees 7.6/10 Good! (679 reviews) [](https://expedia.ca/Hannibal-Hotels-Comfort-Inn-Suites-Hannibal.h64231.Hotel-Information) ![Best Western On The River](https://images.trvl-media.com/lodging/1000000/20000/16300/16249/d6669a71_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western On The River 401 North 3rd Street Hannibal MO CA $139 CA $159 total Mar 25 - Mar 26 includes taxes & fees 8.6/10 Excellent! (1,011 reviews) [](https://expedia.ca/Hannibal-Hotels-Best-Western-On-The-River.h16249.Hotel-Information) ![Sleep Inn & Suites Hannibal West](https://images.trvl-media.com/lodging/12000000/11310000/11309000/11308942/863ee254_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites Hannibal West 105 Lakeside Dr Hannibal MO CA $150 CA $174 total Apr 19 - Apr 20 includes taxes & fees 9.6/10 Exceptional! (1,004 reviews) [](https://expedia.ca/Hannibal-Hotels-Sleep-Inn-Suites.h11308942.Hotel-Information) ## Hotels in Louisiana with star rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 2 properties [](https://expedia.ca/4Star-Louisiana-Hotels.s40-0-d127811.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 5 properties [](https://expedia.ca/3Star-Louisiana-Hotels.s30-0-d127811.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 21 properties [](https://expedia.ca/2Star-Louisiana-Hotels.s20-0-d127811.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Louisiana? > This charming area is the heart of the town, characterised by its well-preserved 19th-century architecture and a welcoming, small-town feel. You'll find a selection of local shops, antique stores, and eateries clustered around these main thoroughfares, making it very convenient for exploring on foot. The district is also home to the historic Clarksville Riverfront, offering pleasant views of the Mississippi River. > > > Couples looking for a relaxing getaway will find this area particularly appealing. The historic district provides a romantic backdrop for strolls, with opportunities to browse unique shops and enjoy meals in local restaurants. Several bed and breakfasts are located within these streets, offering a more intimate and personalised lodging experience. > > > For solo travellers seeking a peaceful retreat with a touch of history, staying in downtown Louisiana offers easy access to local museums and art galleries. ### What are the best hotels in Louisiana that travellers recommend? > The River's Edge Motel, with a 9.0 rating, offers comfortable and clean rooms, as highlighted by guests. The staff are frequently described as friendly and helpful, ensuring a pleasant stay. Amenities include air conditioning, a hydromassage showerhead for relaxation, and self-parking, which is complimentary. The motel also features child-friendly window designs, adding to its appeal for families. Guests appreciate the good value for money this hotel provides. ### What are the best family hotels in Louisiana? > The River's Edge Motel, with a rating of 9.0, offers comfortable and clean rooms with a child-friendly window design. Guests appreciate the free WiFi, complimentary toiletries, and hydromassage showerheads. Free self-parking is also available, and the Mississippi River is located approximately 13.6 km away. > > > Another excellent option is the 3-star The Eagles Nest Inn, which has an impressive 9.4 rating. This hotel provides free self-parking, complimentary toiletries, and bathrobes. It also offers kids' meals and free WiFi, and the Mississippi River is about 14.2 km from the property. ### What are the top pet-friendly hotels in Louisiana? > The River's Edge Motel, with a 9.0 rating, is a great choice as pets are permitted, and it offers convenient free self-parking and complimentary WiFi. Guests frequently mention the comfortable and clean rooms, the friendly and helpful staff, and the good prices. The Mississippi River is located nearby, approximately 13.6 km away. See more [pet-friendly hotels in Louisiana](https://www.expedia.ca/Louisiana-Hotels-Pet-Friendly-Hotel.0-0-d127811-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) ### What are the best budget hotels in Louisiana? > The River's Edge Motel, with an impressive 9.0 rating, offers comfortable and clean rooms, as well as friendly and helpful staff. Guests appreciate the free WiFi, complimentary toiletries, and the convenience of free self-parking. The motel also features hydromassage showerheads and child-friendly window designs. It is located approximately 13.6 km from the Mississippi River. > > > Another great option is the 3-star The Eagles Nest Inn, which boasts an outstanding 9.4 rating. This inn provides amenities such as free WiFi, complimentary toiletries, and bathrobes, ensuring a pleasant stay. Free self-parking is available, and families will find the kids' meal option convenient. It is situated about 14.2 km from the Mississippi River. View all [budget hotels in Louisiana](https://www.expedia.ca/Louisiana-Hotels-Cheap-Hotels.0-0-d127811-tCheapHotels.Travel-Guide-Filter-Hotels) ### What are the best hotels in Louisiana near Mississippi River? > The 3-star Eagles Nest Inn, with a 9.4 rating, is a highly-rated option. It is located 14.2 km from the Mississippi River and offers free self-parking, complimentary toiletries, bathrobes, and free WiFi. The hotel also provides kids' meals, making it very suitable for families. > > > Another good choice is the River's Edge Motel, which has a 9.0 rating. This motel is 13.6 km from the Mississippi River and provides free self-parking, free WiFi, and complimentary toiletries. Guests often mention the comfortable and clean rooms, as well as the friendly and helpful staff. ### When is the best time to go to Louisiana? > Spring in Louisiana brings mild temperatures, great for exploring the town's historic architecture and enjoying the budding nature along the Mississippi River. The blooming flowers add a lovely touch to the scenic views. This season is particularly good for couples looking for a picturesque getaway, perhaps enjoying a stroll through the historic downtown or a scenic drive along the Great River Road. > > > Autumn offers similarly agreeable weather, with comfortable temperatures and the added beauty of changing leaves, especially along the river bluffs. This period is often popular for those interested in local festivals and events, such as the Louisiana Country Colorfest, which showcases regional arts, crafts, and food. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Louisiana hotel booking with Expedia? ### How much is the nightly rate at a Louisiana hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [4 Star Hotels in Elsberry ](https://www.expedia.ca/4Star-Elsberry-Hotels.s40-0-d3000444866.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annada ](https://www.expedia.ca/Annada-Hotels-Luxury-Hotel.0-0-d553248634983192995-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Bellflower Hotels ](https://www.expedia.ca/Bellflower-Hotels.d6351836.Travel-Guide-Hotels) - [Aparthotels in Bowling Green ](https://www.expedia.ca/Bowling-Green-Apart-Hotels.d602836-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Bowling Green ](https://www.expedia.ca/Bowling-Green-Bed-And-Breakfast.d602836-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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