Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri

Louisiana Vacation Rentals

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Our top choices for Louisiana vacation rentals

The Yellow Rose Historic Home

The Yellow Rose Historic Home
Louisiana
9.8 out of 10, Exceptional, (18 reviews)
"Everything was great!"
United States
Brendan R.
The price is CA $350
CA $519 total
includes taxes & fees
Jun 23 - Jun 24
The Yellow Rose Historic Home

Charming 2-bedroom barnloft on hobby farm in Pleasant Hill pittsfield area

Charming 2-bedroom barnloft on hobby farm in Pleasant Hill pittsfield area
Pleasant Hill
The price is CA $183
CA $262 total
includes taxes & fees
Jun 22 - Jun 23
Charming 2-bedroom barnloft on hobby farm in Pleasant Hill pittsfield area

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
9.0 out of 10, Wonderful, (30 reviews)
"Fun themed rooms."
United States
Kelly
The price is CA $242
CA $328 total
includes taxes & fees
Jun 22 - Jun 23
Lighthouse Inn & Suites

Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
10.0 out of 10, Exceptional, (218 reviews)
"The place was affordable, clean and nicely furnished for the five of us. Worked out well for our visit to Hannibal. "
United States
Terry H.
The price is CA $184
CA $351 total
includes taxes & fees
Jun 23 - Jun 24
Peaceful, Country Cottage with Open Floor Plan

Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (13 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
The price is CA $120
CA $397 total
includes taxes & fees
Jun 22 - Jun 23
Vibey home a few blocks from downtown Hannibal

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (51 reviews)
"We enjoyed our overnight stay. It was clean and comfortable"
United States
Charlene
The price is CA $173
CA $279 total
includes taxes & fees
Jun 29 - Jun 30
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.6 out of 10, Exceptional, (19 reviews)
"right in the historic district with a very nice neighbor"
United States
Monica
The price is CA $215
CA $334 total
includes taxes & fees
Jun 23 - Jun 24
The John Sydney House - Family and Pet Friendly Historic Home Downtown

Updated efficiency unit attached to the Parlor on Paris - Rent both and save

Updated efficiency unit attached to the Parlor on Paris - Rent both and save
Hannibal
9.6 out of 10, Exceptional, (5 reviews)
"Great for a weekend get away."
United States
Jordon S.
The price is CA $76
CA $283 total
includes taxes & fees
Jun 22 - Jun 23
Updated efficiency unit attached to the Parlor on Paris - Rent both and save

Papa's Cabin - 40 acres & 5 acre lake!

Papa's Cabin - 40 acres & 5 acre lake!
Middletown
10.0 out of 10, Exceptional, (2 reviews)
"We absolutely loved our stay at the cabin!! So much space to spread out inside, and the property & lake are so peaceful and enjoyable to explore. Though we only spent one night, we really loved it there, and will definitely be back when we are in the area visiting family!"
United States
Scott V.
The price is CA $171
CA $300 total
includes taxes & fees
Jun 25 - Jun 26
Papa's Cabin - 40 acres & 5 acre lake!

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft

Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Hannibal
10.0 out of 10, Exceptional, (3 reviews)
"Pretty place. Awesome location. Had such a good time"
United States
janette b.
The price is CA $209
CA $505 total
includes taxes & fees
Jun 27 - Jun 28
Jacuzzi Tub & Full Kitchen: Dowtown Hannibal Loft
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisiana Hotel Reviews

Find out more about Louisiana

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Louisiana. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

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Frequently asked questions

Are there vacation rentals in Louisiana?

Yes, we offer vacation rentals close to popular local attractions in Louisiana, or you can choose a more remote option if you're looking for a relaxing stay. Nature enthusiasts will enjoy the riverfront in Louisiana.

What are some of the best vacation rentals in Louisiana?

The Yellow Rose Historic Home: This highly rated vacation home rental in Louisiana offers a selection of games, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Louisiana?

While you're exploring the area, Mississippi River and Clarksville Riverfront Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Clarksville State Game Refuge and Ramsey Creek Church.

What are vacation rentals like in Louisiana?

Vacation rentals are private properties you can book for several days or longer in Louisiana. Vacation rentals provide amenities such as hot tubs, fire pits, and patios so you'll have everything you need. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive choice for family trips or small group gatherings.