Title: 4 Stars Hotels in Louisiana, Missouri  - Find Cheap Louisiana Hotels With 4 Stars | Expedia.ca

[Louisiana Travel Guide](https://expedia.ca/Louisiana.dx127811)[Hotels in Louisiana](https://expedia.ca/Louisiana-Hotels.d127811.Travel-Guide-Hotels)[Vacation Rentals in Louisiana](https://expedia.ca/Louisiana-Vacation-Rentals.d127811.Travel-Guide-VacationRentals)[Flights to Louisiana](https://expedia.ca/Cheap-Flights-To-Louisiana.d127811.Travel-Guide-Flights)[Louisiana Car Rentals](https://expedia.ca/Car-Rentals-In-Louisiana.d127811.Car-Rental-Guide)[Louisiana Vacation Packages](https://expedia.ca/Louisiana.d127811.Destination-Travel-Guides)

![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# 4 Stars Hotels in Louisiana, Missouri 

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## Check availability on Louisiana 4 Star Hotels

Tonight

[Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-12-18&endDate=2025-12-19&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 19 - Dec 20](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-12-19&endDate=2025-12-20&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-12-19&endDate=2025-12-21&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=127811&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Learn more about Louisiana

Like rivers? Get away to relaxing Louisiana! 

[See all hotels in Louisiana](https://www.expedia.ca/Hotel-Search?startDate=2026-01-02&endDate=2026-01-03&adults=2&regionId=127811)

![Open swing span of Louisiana railroad bridge across the upper Mississippi near the town of Louisiana in Missouri](https://images.trvl-media.com/place/127811/d3a11af1-a4bc-4d21-8f62-58cf4c9cc04d.jpg?impolicy=fcrop&w=900&h=569&p=1&q=high)

## Top Louisiana Hotel Reviews

![Lighthouse Inn & Suites](https://images.trvl-media.com/lodging/106000000/105130000/105120300/105120258/fb550013_y.jpg)

### Lighthouse Inn & Suites

10/10 Excellent

"Great experience, clean room. "

[](https://expedia.ca/Hannibal-Hotels-Lighthouse-Inn-Suites.h105120258.Hotel-Information)

## Find out more about Louisiana

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Louisiana are calling your name. Known for providing first-rate service in amazing locations, each of the Louisiana 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Louisiana. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Louisiana, Missouri, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Louisiana hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### How much does it cost to stay in a 4-star hotel in Louisiana?

> - Search for the lowest price

### What's the difference between 5-star and 4-star hotels in Louisiana?

### Does Louisiana have any 4-star all-inclusive resorts?

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