Name: 21C Museum Hotel St Louis
Price range: CA $172
Rating: 9

Your Glen Carbon Vacation

Take the stress out of organizing your next exciting adventure with a Glen Carbon vacation package. Whether you're interested in its cuisine, history, art or something else, you'll find countless exciting experiences to delve into. You'll want to go sightseeing during your trip to Glen Carbon. Carve out some time for big-name attractions such as Edwardsville Arts Center, Villa Marie Winery & Banquet Center and St. Andrews Episcopal Church. Stop dreaming and start doing. Browse the range of options on Expedia today and put your Glen Carbon vacation plans in motion!

Top Glen Carbon Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Best Western St. Louis Inn

CA $1,133

per person

Apr 10 - Apr 17

just found

Roundtrip non-stop flight included

Toronto (YYZ) to St. Louis (STL)

8/10 Very Good! (1,001 reviews)

Room was spotless staff are friendly breakfast with hot eggs, sausage,etc.

Reviewed on Mar 1, 2026

The Wildwood Hotel

CA $1,240

per person

Apr 10 - Apr 17

just found

Roundtrip non-stop flight included

Toronto (YYZ) to St. Louis (STL)

9.2/10 Wonderful! (1,626 reviews)

We stayed for 1 night, overall good experience. The pool water was pretty cold and the hot tub is small (max occupancy 2). I was a little disappointed in the continental breakfast. Make your own waffles, cereal, and assorted breads. Wished for a larger selection and ready-made hot foods.

Reviewed on Mar 8, 2026

Hampton Inn St. Charles St. Peters

CA $1,311

per person

Apr 10 - Apr 17

just found

Roundtrip non-stop flight included

Toronto (YYZ) to St. Louis (STL)

8/10 Very Good! (1,002 reviews)

Soaps/lotion in bathroom were low or empty upon check in. Too heavy on the scent of cleaning solution, gave me a headache. Dark roast coffee was weak.

Reviewed on Mar 3, 2026

MainStay Suites St. Louis - Galleria

CA $1,185

per person

Apr 10 - Apr 17

just found

Roundtrip non-stop flight included

Toronto (YYZ) to St. Louis (STL)

6.8/10 (110 reviews)

I needed to be out of the house because Flooring was put down. This place was perfect for that. It was a large room with a bedroom area, a full kitchen and a loveseat chair and TV. I could bring my cat and it was very comfortable not five star because it isn’t nice enough for that. And on the weekends, I have to say there was a lot of people there, but it was still pretty quiet.

Reviewed on Feb 17, 2026

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

CA $1,186

per person

Apr 10 - Apr 17

just found

Roundtrip non-stop flight included

Toronto (YYZ) to St. Louis (STL)

8/10 Very Good! (1,114 reviews)

Family and I stayed for a quick trip to St. Louis. The property is easy to get in and out of which is a plus. It was less than twenty minutes to everywhere we wanted to be which was also good. The place was clean, staff friendly and overall a pleasant place to stay. My only issue was that on the Saturday we were checking out breakfast didn’t start until 0700 which was around the time we were heading out. Regardless, we’ll stay again the next time we’re in St. Louis.

Reviewed on Mar 9, 2026

Ready to book your vacation to Glen Carbon?

Choose your dates

Glen Carbon Hotel Deals

Clayton Plaza Hotel & Extended Stay

7750 Carondelet Avenue St. Louis MO

Fully refundableReserve now, pay when you stay

CA $142

CA $166 total

Mar 22 - Mar 23

includes taxes & fees

8.8/10 Excellent! (3,123 reviews)

The water pressure in our room's shower was the worst I've ever experienced.

Reviewed on Mar 9, 2026

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

CA $183

CA $214 total

Mar 15 - Mar 16

includes taxes & fees

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

CA $172

CA $208 total

Apr 5 - Apr 6

includes taxes & fees

9/10 Wonderful! (1,646 reviews)

Stay was great and the hotel was a close walk to Enterprise Center.

Reviewed on Mar 9, 2026

See all 1,554 properties in Glen Carbon

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.