Title: Panama Vacation Rentals from CA $85: Short-Term Rentals for 2025 | Expedia.ca [Panama Travel Guide](https://expedia.ca/Panama.dx142)[Panama Hotels](https://expedia.ca/Destinations-In-Panama.d142.Hotel-Destinations)[Panama Flights](https://expedia.ca/Destinations-In-Panama.d142.Flight-Destinations)[Panama Car Rentals](https://expedia.ca/Destinations-In-Panama.d142.Car-Rental-Destinations)[Panama Vacations](https://expedia.ca/Panama.d142.Destination-Travel-Guides) ![Panama which includes tropical scenes, island images and landscape views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/25000/25685-Panama.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Panama Vacation Rentals ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Panama ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Panama City [](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals) ![](https://mediaim.expedia.com/destination/1/1d8a91c9ba3e2729b384542dbcd5f2f4.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Colon [](https://expedia.ca/Colon-Vacation-Rentals.d601867.Travel-Guide-VacationRentals) ![](https://mediaim.expedia.com/destination/2/504facaece8a8de4b5e66a51bfdb8196.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### El Valle de Anton [](https://expedia.ca/El-Valle-De-Anton-Vacation-Rentals.d6053180.Travel-Guide-VacationRentals) ![](https://mediaim.expedia.com/destination/1/b0242759ce82d4f0d6f5123d7c510e46.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Rio Hato [](https://expedia.ca/Rio-Hato-Vacation-Rentals.d6246042.Travel-Guide-VacationRentals) ## Top Vacation Rentals in in Panama ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f6eaf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites Costa del Este 9.4/10 Exceptional (110) "Great Property, friendly staff, easy parking and equipped kitchen " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher CA $84 CA $157 total includes taxes & fees Nov 8 - Nov 9 [](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/edba2188.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | View from room](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/5cdc54c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/a4be5f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/79000000/78290000/78283500/78283415/568d88f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panama Bella Vista 7.6/10 Good (182) "Excellent location and the views were amazing" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) PADMAWATTIE CA $47 CA $158 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama.h78283415.Hotel-Information) ![Standard Apartment | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/0a056e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/b2adfd51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/29d0d0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/f71ce331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites Bella Vista 8.8/10 Excellent (475) "Good location, quick walk to the subway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lynden CA $126 CA $139 total includes taxes & fees Nov 6 - Nov 7 [](https://www.expedia.ca/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duplex | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/762cceb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments Santa Ana 9.4/10 Exceptional (48) "Great stay, would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke CA $101 CA $112 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Deluxe Apartment | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7d5bd8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Apartment | Beach/ocean view](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/a7c64715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/077501d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/f7211254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panamá by Boutique Apartments Bella Vista 8.2/10 Very good (43) "Great place , very clean all good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) harley CA $93 CA $227 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information) ![Superior Double Room | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c337dae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Queen Suite | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/5b01afd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Double Room | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/cb84ac89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Isabela Suites Casco Viejo 10/10 Exceptional (162) "The hotel is beautiful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Agnes CA $176 CA $196 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09H) | Living area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (10D) | Living area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/96b85842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11I)](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/0f7befd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco by Wynwood House San Francisco 9.2/10 Wonderful (52) "This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mario CA $142 CA $194 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/7a081d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/ed9d8c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar San Francisco 7.4/10 Good (145) "GORGEOUS view!!! And very spacious " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) christine CA $54 CA $248 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment (3G) | Balcony](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/b4a2ec38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Dining room](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/e16a4424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, toaster, cookware/dishes/utensils](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/f5328136.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3G) | Living area](https://images.trvl-media.com/lodging/101000000/100600000/100591500/100591449/8ac950b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cuadra by Wynwood House El Chorrillo 9.2/10 Wonderful (41) "Nice place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tesha CA $105 CA $150 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Panama-City-Hotels-La-Cuadra-By-Wynwood-House.h100591449.Hotel-Information) ![Studio, 1 King Bed, Non Smoking, Connecting Rooms](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Queen Bed with Sofa bed, Non Smoking, Kitchen](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/faee5c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/f0ebed1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas Casco Viejo 9.4/10 Exceptional (165) "Great Food , excellent bar.... soft beds and pillows.... five stars will come again !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul CA $174 CA $191 total includes taxes & fees Oct 28 - Oct 29 [](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Deluxe Apartment](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/b8edc80a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment | Private kitchen](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/7d5fb04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Living area](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97957e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | Dining room](https://images.trvl-media.com/lodging/101000000/100590000/100587800/100587737/97ac72d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Moderna by Wynwood House Casco Viejo 7.4/10 Good (37) "The nightlife around there was incredible" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix CA $63 CA $104 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Panama-City-Hotels-La-Moderna-By-Wynwood-House.h100587737.Hotel-Information) ![Apartment (CC4B) | Balcony](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/64939a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC1A)](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/d5409722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC2B) | Living area](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/f49b7db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CC3B) | Private kitchen](https://images.trvl-media.com/lodging/100000000/99230000/99229300/99229225/5e7a29e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Contemporanea by Wynwood House Casco Viejo 8.6/10 Excellent (19) "Great place!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jad CA $143 CA $192 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99229225.Hotel-Information) ![Apartment, 2 Bedrooms (2C)](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3a166248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (4B) | Dining room](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/e8a22a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1B) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/5945d7c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1B) | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/350b1bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House Casco Viejo 8.4/10 Very good (44) "I always love to stay at Wynwood properties in Panama " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto B CA $71 CA $113 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Apartment, 2 Bedrooms (CM2) | Private kitchen](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/dfb3f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms (CM5)](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/f82421c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM4) | Terrace/patio](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/9659c91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (CM1) | Dining room](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/242a1c2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Mallet by Wynwood House Casco Viejo 9.8/10 Exceptional (24) " It was very relaxing to stay at the historical and cutely renovated apartment. Great aesthetic. Lively apartment, very well decorated! Right the middle of everything in the beautiful town of Casco Veijo. Vibrant lanes, boutique stores, cafes and restaurants near by. We had an amazing time staying for 2 nights at this apartment. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Navyatha CA $196 CA $251 total includes taxes & fees Oct 29 - Oct 30 [](https://www.expedia.ca/Panama-City-Hotels-Casa-Mallet-By-Wynwood-House.h99778891.Hotel-Information) ![Outdoor pool, free cabanas, sun loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Living area](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a2b1fb98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/32689428.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/b3283f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panama & Arts Tower Bella Vista 9.4/10 Exceptional (40) "Yoo Panama is ideally situated overlooking the Bay. The condo is spacious and extremely clean. A true luxury home away from home. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Angela [](https://www.expedia.ca/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/576f28cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SUITE ALBANY](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/e250353b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![SUITE KINGSTON | Living area](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/913700d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/101000000/100640000/100639500/100639469/2c441825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ESHEL SUITES PANAMA San Francisco 10/10 Exceptional (5) "Loved the property and the location, it was clean , nice and I really enjoyed my stay there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aron [](https://www.expedia.ca/Panama-City-Hotels-ESHEL-SUITES-PANAMA.h100639469.Hotel-Information) ![Apartment (1D) | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/c78eb228.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2C) | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/8f7fd7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/b50fc181.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2D) | Private kitchen](https://images.trvl-media.com/lodging/105000000/104150000/104145400/104145345/0c622720.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa La Costa By Wynwood House Casco Viejo 8.4/10 Very good (18) "Clean apartment, beautiful views, very helpful staff. Not in an ideal location if you go out at night. Warmed several times about the area and being out at night. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Harold CA $115 CA $173 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Panama-City-Hotels-Casa-La-Costa-By-Wynwood-House.h104145345.Hotel-Information) ![Design Suite, 1 King Bed, Mountain View](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/903374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite | Private kitchenette](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/29a7e7da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/19d8b56c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, 1 King Bed, Garden View | Living area](https://images.trvl-media.com/lodging/96000000/95050000/95043600/95043574/a6c217b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### El Cielo by Villa Alejandro Boquete 9.6/10 Exceptional (81) "Nice stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carlos CA $82 CA $120 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Boquete-Hotels-El-Cielo-By-Villa-Alejandro.h95043574.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (8B) | Private kitchen](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b8e57e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (8B) | Private kitchen](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/46fac3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B)](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/155ac5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa San Francisco 7.6/10 Good (23) "I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shamia CA $75 CA $189 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Honeymoon Studio, Hot Tub, Valley View](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/f1920aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Studio Suite, 1 Queen Bed, Kitchenette, Garden Area | In-room dining](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/w4030h2268x0y0-0bf2c10e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/c5c10649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Studio, Hot Tub, Valley View](https://images.trvl-media.com/lodging/47000000/46560000/46550500/46550459/b46898c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Alejandro Boquete 8.8/10 Excellent (122) "Priced right, easy walk to town, safe, quiet & overall great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $50 CA $85 total includes taxes & fees Oct 26 - Oct 27 [](https://www.expedia.ca/Boquete-Hotels-Villa-Alejandro.h46550459.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-08&endDate=2025-11-09®ionId=142&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Vacation-Rental-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Panama.d142.Vacation-Rental-Destinations) ## Top Panama Hotel Reviews ![Arcadia Condo Suites](//images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg) ### Arcadia Condo Suites 10/10 Excellent "Loved my condo apartment and the view was amazing!" [](https://expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "Staff was very nice and helpful." [](https://expedia.ca/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Gran Evenia Bijao & Convention Center](//images.trvl-media.com/lodging/73000000/72100000/72094600/72094557/bafae9a3_y.jpg) ### Gran Evenia Bijao & Convention Center 10/10 Excellent "Nice experience " [](https://expedia.ca/Rio-Hato-Hotels-Bijao-Beach-Resort.h72094557.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "👍" [](https://expedia.ca/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Marriott Panama Hotel](//images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Great service and property " [](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Studio Coliving](//images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/e86f18bd_y.jpg) ### Studio Coliving 10/10 Excellent "My second stay and have never regretted it. A good value for the price." [](https://expedia.ca/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "A nice hotel with plenty of shopping and restaurants in the area" [](https://expedia.ca/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Staff was nice but not in any hurry" [](https://expedia.ca/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "The room was very clean and breakfast was fresh and good. Would stay there again." [](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ## Find out more about Panama **Everything you need to know about** **Panama** **vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **Panama vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama vacation rentals we have selected for you start as low as CA $85 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Panama rentals** At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Popular Panama Cities - All accommodation types in Panama - [Panama City Vacation Rentals](https://expedia.ca/Panama-City-Vacation-Rentals.d2897.Travel-Guide-VacationRentals) - [Bocas del Toro Vacation Rentals](https://expedia.ca/Bocas-Del-Toro-Vacation-Rentals.d6023445.Travel-Guide-VacationRentals) - [Rio Hato Vacation Rentals](https://expedia.ca/Rio-Hato-Vacation-Rentals.d6246042.Travel-Guide-VacationRentals) - [Colon Vacation Rentals](https://expedia.ca/Colon-Vacation-Rentals.d601867.Travel-Guide-VacationRentals) - [Boquete Vacation Rentals](https://expedia.ca/Boquete-Vacation-Rentals.d500194.Travel-Guide-VacationRentals) - [El Valle de Anton Vacation Rentals](https://expedia.ca/El-Valle-De-Anton-Vacation-Rentals.d6053180.Travel-Guide-VacationRentals) - [Bastimentos Vacation Rentals](https://expedia.ca/Bastimentos-Vacation-Rentals.d829296964305711104.Travel-Guide-VacationRentals) - 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