Title: Top Hotels in Wayne County | Expedia.ca [Vacation Rentals in Wayne County](https://expedia.ca/Destinations-In-Wayne-County.d553248635976433836.Vacation-Rental-Destinations)[Wayne County Car Rentals](https://expedia.ca/Destinations-In-Wayne-County.d553248635976433836.Car-Rental-Destinations)[Wayne County Vacations](https://expedia.ca/Wayne-County.d553248635976433836.Destination-Travel-Guides) ![Sunrise from the duck blind. ](https://images.trvl-media.com/place/183505/9493e565-66da-46c4-8222-30a8f5da22bb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by JG Morris # Search Wayne County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Wayne County ![](https://mediaim.expedia.com/destination/2/a6135d9f1717ada26d9944dd5bb40459.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Wappapello [](https://expedia.ca/Wappapello-Hotels.d183505.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Dec 22 - Dec 23](https://www.expedia.ca/Hotel-Search?regionId=553248635976433836&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 23 - Dec 24](https://www.expedia.ca/Hotel-Search?regionId=553248635976433836&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976433836&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635976433836&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Wayne-County.d553248635976433836.Hotel-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Wayne-County.d553248635976433836.Hotel-Destinations) ## Top Wayne County Hotel Reviews ![Holiday Inn Poplar Bluff by IHG](https://images.trvl-media.com/lodging/2000000/1230000/1222200/1222183/e91b57a7_y.jpg) ### Holiday Inn Poplar Bluff by IHG 10/10 Excellent "The front desk woman was great " [](https://expedia.ca/Poplar-Bluff-Hotels-Holiday-Inn-Poplar-Bluff.h1222183.Hotel-Information) ![Travelodge by Wyndham Dexter](https://images.trvl-media.com/lodging/1000000/90000/84800/84779/8be70c86_y.jpg) ### Travelodge by Wyndham Dexter 10/10 Excellent "Staff was helpful and kind. The room was clean as well as the whole Hotel, although they should move the smoking area from right at the enrty way of the hotel." [](https://expedia.ca/Sikeston-Hotels-Travelodge-By-Wyndham-Dexter.h84779.Hotel-Information) ![Motel 6 Poplar Bluff, MO](https://images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg) ### Motel 6 Poplar Bluff, MO 10/10 Excellent "Staff was amazing and super nice. Room was very clean. " [](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![Drury Inn & Suites Poplar Bluff](https://images.trvl-media.com/lodging/1000000/50000/41600/41515/b034b164_y.jpg) ### Drury Inn & Suites Poplar Bluff 10/10 Excellent "The room was Great!" [](https://expedia.ca/Poplar-Bluff-Hotels-Drury-Inn-Suites-Poplar-Bluff.h41515.Hotel-Information) ![Fairfield Inn & Suites by Marriott Poplar Bluff](https://images.trvl-media.com/lodging/29000000/28810000/28807300/28807257/76c46720_y.jpg) ### Fairfield Inn & Suites by Marriott Poplar Bluff 10/10 Excellent "Clean, friendly.. not to expensive " [](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information) ![Hampton Inn Poplar Bluff](https://images.trvl-media.com/lodging/10000000/9830000/9827800/9827793/2dc5e17d_y.jpg) ### Hampton Inn Poplar Bluff 10/10 Excellent "Every single time I come to this location, it always exceeds my expectations. It's always clean.They always have hot coffee and they are super friendly!! Never have anything bad to say about them" [](https://expedia.ca/Poplar-Bluff-Hotels-Hampton-Inn-Poplar-Bluff-Mo.h9827793.Hotel-Information) ![Camp Stonebass-Lake House-Hottub](https://images.trvl-media.com/lodging/116000000/115660000/115656000/115655964/3255fa08_y.jpg) ### Camp Stonebass-Lake House-Hottub 10/10 Excellent "The place was perfect for spending time with family. It was clean and comfortable. " [](https://expedia.ca/Wappapello-Hotels-Camp-Stonebass-Lake-House-Hottub.h115655964.Hotel-Information) ![Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided](https://images.trvl-media.com/lodging/90000000/89710000/89701300/89701234/de7e2348_y.jpg) ### Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided 10/10 Excellent "This place is amazing! We've stayed at a lot of different VRBOs and this is by far one of the best! Thanks for having us and we'll definitely be back" [](https://expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) ![Hampton Inn By Hilton Dexter](https://images.trvl-media.com/lodging/120000000/119380000/119371000/119370952/w3836h2556x4y4-c3d811b2_y.jpg) ### Hampton Inn By Hilton Dexter 10/10 Excellent "Staff was helpful and professional. The rooms were clean and comfortable " [](https://expedia.ca/Dexter-Hotels-Hampton-Inn-By-Hilton-Dexter.h119370952.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Wayne County - [Piedmont Hotels ](https://expedia.ca/Piedmont-Hotels.d3000445413.Travel-Guide-Hotels) - [Wappapello Hotels ](https://expedia.ca/Wappapello-Hotels.d183505.Travel-Guide-Hotels) - [Patterson Hotels ](https://expedia.ca/Patterson-Hotels.d553248635975853657.Travel-Guide-Hotels) - [Greenville Hotels ](https://expedia.ca/Greenville-Hotels.d553248634983564794.Travel-Guide-Hotels) - [Mill Spring Hotels ](https://expedia.ca/Mill-Spring-Hotels.d553248634983294338.Travel-Guide-Hotels) - [Lowndes Hotels ](https://expedia.ca/Lowndes-Hotels.d845959773057740800.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Lake Wappapello ](https://expedia.ca/Lake-Wappapello-Hotels.0-l553248621532648460-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain National Forest ](https://expedia.ca/Mark-Twain-National-Forest-Hotels.0-l553248635976468503-0.Travel-Guide-Filter-Hotels) - [Hotels near Johnson's Shut-ins State Park ](https://expedia.ca/Johnsons-Shut-Ins-State-Park-Hotels.0-l553248621555612544-0.Travel-Guide-Filter-Hotels) - [Hotels near Ozark National Scenic Riverways ](https://expedia.ca/Ozark-National-Scenic-Riverways-Hotels.0-l6093451-0.Travel-Guide-Filter-Hotels) - [Hotels near Current River ](https://expedia.ca/Current-River-Hotels.0-l553248635976196024-0.Travel-Guide-Filter-Hotels) - [Hotels near Taum Sauk Mountain State Park ](https://expedia.ca/Taum-Sauk-Mountain-State-Park-Hotels.0-l553248621532648466-0.Travel-Guide-Filter-Hotels) - [Hotels near Big Spring ](https://expedia.ca/Big-Spring-Hotels.0-l553248621532648457-0.Travel-Guide-Filter-Hotels) - [Hotels near K Bridge Recreation Area ](https://expedia.ca/K-Bridge-Recreation-Area-Hotels.0-l6282501-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Wayne County - [Cabin Rentals in Wayne County ](https://expedia.ca/Wayne-County-Cabins.d553248635976433836-aaCabins.Travel-Guide-Accommodation) - [Vacation Homes in Wayne County ](https://expedia.ca/Wayne-County-Private-Vacation-Homes.d553248635976433836-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cottages in Wayne County ](https://expedia.ca/Wayne-County-Cottages.d553248635976433836-aaCottages.Travel-Guide-Accommodation) - [Apartments in Wayne County ](https://expedia.ca/Wayne-County-Apartments.d553248635976433836-aaApartments.Travel-Guide-Accommodation) - [Motels in Wayne County ](https://expedia.ca/Wayne-County-Motels.d553248635976433836-aaMotels.Travel-Guide-Accommodation) - [Lodges in Wayne County ](https://expedia.ca/Wayne-County-Lodges.d553248635976433836-aaLodges.Travel-Guide-Accommodation) - [RV Parks in Wayne County ](https://expedia.ca/Wayne-County-RV-Parks.d553248635976433836-aaRVParks.Travel-Guide-Accommodation) - [Condo Rentals in Wayne County ](https://expedia.ca/Wayne-County-Condos.d553248635976433836-aaCondos.Travel-Guide-Accommodation) ### Explore more hotels - [Sam A Baker State Park ](https://expedia.ca/Patterson-Hotels-Sam-A-Baker-State-Park.h114277672.Hotel-Information) - [Private lake, beach & hot tub, romantic getaway or family vaca ](https://expedia.ca/Wappapello-Hotels-Private-Lake.h89711320.Hotel-Information) - [Camp Minnow Beach House ](https://expedia.ca/Wappapello-Hotels-Camp-Minnow-Beach-House.h96471085.Hotel-Information) - [Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided ](https://expedia.ca/Secluded-In-The-Woods.h89701234.Hotel-Information) - [Cabin 1 queen bed with a separate bedroom with a double bed ](https://expedia.ca/Piedmont-Hotels-Cabin-1-Queen-Bed-With-A-Separate-Bedroom-With-A-Double-Bed.h69804672.Hotel-Information) - [Camp Stonebass-Lake House-Hottub ](https://expedia.ca/Wappapello-Hotels-Camp-Stonebass-Lake-House-Hottub.h115655964.Hotel-Information) - [Rustic Cabin in Hunters' Paradise! ](https://expedia.ca/Mill-Spring-Hotels-Rustic-Cabin-In-Hunters-Paradise.h57521765.Hotel-Information) - ['the Lakehouse' Lovely Wappapello Country Home! ](https://expedia.ca/Wappapello-Hotels-Lovely-Wappapello-Country-Home-Near-Lake.h93537801.Hotel-Information) - [Motel 6 Poplar Bluff, MO ](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) - [Fairfield Inn & Suites by Marriott Poplar Bluff ](https://expedia.ca/Poplar-Bluff-Hotels-Fairfield-Inn-Suites-By-Marriott-Poplar-Bluff.h28807257.Hotel-Information) [See a list of all hotels in Wayne County](https://expedia.ca/All-Wayne-County-Hotels.d553248635976433836.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Wayne County on Expedia.com ](https://www.expedia.com/Destinations-In-Wayne-County.d553248635976433836.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Golf Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Golf-Hotel.0-0-d178304-tGolfHotel.Hotel-Filter-Destinations) - [Oceanfront Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Oceanfront-Hotels.0-0-d178304-tOceanfrontHotels.Hotel-Filter-Destinations) - [Hotels near GEHA Field at Arrowhead Stadium](https://expedia.ca/GEHA-Field-At-Arrowhead-Stadium-Hotels.0-l6058069-0.Travel-Guide-Filter-Hotels) - [Orange County hotel](https://expedia.ca/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All Inclusive Resorts and Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Downtown St. Louis hotels](https://expedia.ca/Downtown-St-Louis-St-Louis-Hotels.0-n800136-0.Travel-Guide-Filter-Hotels) - [Luxury Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Luxury-Hotel.0-0-d178304-tLuxuryHotel.Hotel-Filter-Destinations) - [Mountain Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Mountain-Hotels.0-0-d178304-tMountainHotels.Hotel-Filter-Destinations) - [San Diego County hotel](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Hotel-Destinations) - [Family Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Family-Hotel.0-0-d178304-tFamilyHotel.Hotel-Filter-Destinations) - [Hotels near Women's and Children's Hospital](https://expedia.ca/Womens-And-Childrens-Hospital-Hotels.0-l553248635974865886-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Cheap-Hotels.0-0-d178304-tCheapHotels.Hotel-Filter-Destinations) - [Power and Light District hotels](https://expedia.ca/Power-And-Light-District-Kansas-City-Hotels.0-n6162504-0.Travel-Guide-Filter-Hotels) - [Downtown Kansas City hotels](https://expedia.ca/Downtown-Kansas-City-Kansas-City-Hotels.0-n6058828-0.Travel-Guide-Filter-Hotels) - [Beach Hotel in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County-Beach-Hotel.0-0-d178304-tBeachHotel.Hotel-Filter-Destinations) Flights - [Flights to Orange County](https://expedia.ca/Destinations-In-Orange-County.d603224.Flight-Destinations) - [Flights to San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Flight-Destinations) Cars - [Car rentals in San Diego County](https://expedia.ca/Destinations-In-San-Diego-County.d178304.Car-Rental-Destinations) - [Car rental Kansas City Airport (MCI)](https://expedia.ca/Car-Rentals-In-Kansas-City-Intl.d4801357.Car-Rental-Guide) Cruises - [Cruises from San Diego County](https://expedia.ca/Cruises-from-San-Diego-County.d178304.Cruise-Departure-Port) Activities - [Things to do in Baldwin County](https://expedia.ca/Things-To-Do-In-Baldwin-County.d553248635976432245.Travel-Guide-Activities) - [Things to do in San Diego County](https://expedia.ca/Things-To-Do-In-San-Diego-County.d178304.Travel-Guide-Activities) - [Things to do in High Ridge](https://expedia.ca/Things-To-Do-In-High-Ridge.d553248634983579370.Travel-Guide-Activities) - [Things to do in Orange County](https://expedia.ca/Things-To-Do-In-Orange-County.d603224.Travel-Guide-Activities) - [Things to do in Levy County](https://expedia.ca/Things-To-Do-In-Levy-County.d553248635976432502.Travel-Guide-Activities) Packages - [San Diego County Vacations](https://expedia.ca/San-Diego-County.d178304.Destination-Travel-Guides) General - [Visit Downtown St. Louis](https://expedia.ca/St-Louis-Downtown-St-Louis.dx800136) - [Visit Downtown Kansas City](https://expedia.ca/Kansas-City-Downtown-Kansas-City.dx6058828) - [Visit Parkville](https://expedia.ca/Parkville.dx9973) - [Visit Orange County](https://expedia.ca/Orange-County.dx603224) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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