Find Hotels by Guesthouse Inns in St. Charles
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
Sep 22 - Sep 23Tomorrow
Sep 23 - Sep 24This weekend
Sep 25 - Sep 27Next weekend
Oct 2 - Oct 4
Save an average of 15% on thousands of hotels when you're signed in
Top St. Charles Hotel Reviews
AmericInn by Wyndham Rochester Near Mayo Clinic
10/10 Excellent
"Easy shuttle access to Mayo, At. Mary's appointments"
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
10/10 Excellent
"Excelente muy bien ubicado"
Med City Inn & Suites - Mayo Clinic Area
10/10 Excellent
"They were very accommodating when my Mayo Clinic appointments were done early."
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
10/10 Excellent
"We enjoyed our stay. The breakfast was wonderful. We were disappointed the hot tub only ran for the first evening though and was down for maintenance after. And the exercise room was a bit grimy"
Hyatt House Rochester/Mayo Clinic Area
10/10 Excellent
"Enjoyed my stay Will return"
Brentwood Inn & Suites
8/10 Good
"Easy shuttle service to Mayo Clinic."
Hampton Inn Rochester-South
10/10 Excellent
"Clean room and hotel. Breakfast was great"
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
10/10 Excellent
"The hotel was clean and quiet. We were happy also to have a shuttle to the Mayo Clinic"
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
10/10 Excellent
"Was there for a surgery at the Mayo and they were so helpful and accommodating. Very grateful for the facility and the staff"
Explore a world of travel with Expedia
- Condo Rentals in Altura
- Castles in Winona
- Motels in Rochester
- Even Hotel Rochester
- Apartments in Elba
- Staybridge Suites Rochester
- B&B in Rollingstone
- Hotels with Balconies in Rochester
- Hostels in Rochester
- Hotels with Free Airport Shuttle in Rochester
- Cheap Hotels in Rochester
- The Exchange 21
- Family Hotels in Rochester
- Apartments in Dover
- Mayo Discount! 4 bed
- La Quinta Inn & Suites Hotels in Red Wing
- Lanesboro Hotels
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Pet-Friendly Hotels in Rochester
- Upscale King Suite—Steps from Mayo Clinic Hospital
- Historic Downtown Winona Hotels
- Quality Inn near Medical Center
- Luxury Hotels in Rochester
- The Berkman
- Hotels with Kitchenettes in Rochester
- Rochester Hotels
- St. Charles Hotels
- Lgbt Friendly Hotels in Northrup
- Hotel Indigo Rochester – Mayo Clinic Area by IHG
- Apartments in Rushford
- Apartments in Goodview
- Hyatt House Rochester/Mayo Clinic Area
- Spa Hotels in Winona
- Hotels with Waterslides in Rochester
- Waterpark Hotels in Rochester
- Comfort Inn & Suites Rochester South Mayo Clinic
- Spa Hotels in Rochester
- Luxury King Suite—Steps from Mayo Clinic Hospital
- Cheap Hotels in Winona
- Hotels near St. Mary's University of Minnesota
- Cabin Rentals in Rochester
- All Inclusive Resorts and in Rochester
- Spark by Hilton Rochester South
- Winona Hotels
- Hotels near Mayo Clinic
- Med City Inn & Suites
- Flights from Berlin (BER) to Rochester (RST)
- Flights from Minot (MOT) to Rochester (RST)
- Flights from Vero Beach (VRB) to Rochester (RST)
- Flights from Toronto (YYZ) to Rochester (RST)
- Flights from Montreal (YUL) to Rochester (RST)
- Flights to Lanesboro
- Flights from Ottawa (YOW) to Rochester (RST)
- Flights from Burlington (BTV) to Rochester (RST)
- Flights from Oshawa (YOO) to Rochester (RST)
- Flights from Lakeland Intl. Airport (LAL) to Rochester (RST)
- Flights from Edmonton (YEG) to Rochester (RST)
- Flights from Huatulco (HUX) to Rochester (RST)
- Flights from New York (LGA) to Rochester (RST)
- Flights from Victoria (YYJ) to Rochester (RST)
- Flights from Regina (YQR) to Rochester (RST)
- Flights from Fort Myers (RSW) to Rochester (RST)
- Delta Toronto (YYZ) to Rochester (RST) flights
- Flights from Timmins (YTS) to Rochester (RST)
- Flights from Vancouver (YVR) to Rochester (RST)
- Flights from Kelowna (YLW) to Rochester (RST)
- Flights from Chicago (ORD) to Rochester (RST)
- Flights from Grand Forks (GFK) to Rochester (RST)
- Flights from Buffalo (BUF) to Rochester (RST)
- Flights from Calgary (YYC) to Rochester (RST)
- Flights from Detroit (DTW) to Rochester (RST)
- Flights to Rochester Intl.
- Flights from Waterloo (ALO) to Rochester (RST)
- Flights from Minneapolis (MSP) to Rochester (RST)
- Flights from Hamilton (YHM) to Rochester (RST)
- Flights from Seattle (SEA) to Rochester (RST)
- Flights from St. George (SGU) to Rochester (RST)
- Flights from Atlanta (ATL) to Rochester (RST)
- Flights from Lewiston
- Flights from Saskatoon (YXE) to Rochester (RST)
- Flights from Lima (LIM) to Rochester (RST)
- Flights from International Falls (INL) to Rochester (RST)
- Flights from Winnipeg (YWG) to Rochester (RST)
- Flights from Thunder Bay (YQT) to Rochester (RST)
- Flights from Los Angeles (LAX) to Rochester (RST)
- Flights from Florence (FLO) to Rochester (RST)
- Flights from Abbotsford (YXX) to Rochester (RST)
- Flights from Sheridan (SHR) to Rochester (RST)
- Flights from Kitchener (YKF) to Rochester (RST)
- Flights to Rochester
- Flights from Peterson
- Flights from Sudbury (YSB) to Rochester (RST)
- Flights to Winona