A sunset over a beach with a pier and people walking on the sand.

Southwest Coast Florida Vacation Rentals

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Dates

November 2026

December 2026

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Our top choices for Southwest Coast Florida vacation rentals

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

1. StudioRes by Marriott Fort Myers Airport

Fort Myers

Joseph

CA $112 total

includes taxes & fees

Nov 16 - Nov 17

A balcony with a TV, a chair, and a view of a beach with a pier.

2. Edison Beach House

Fort Myers Beach

Joshua

CA $297 total

includes taxes & fees

Nov 17 - Nov 18

A pool area with lounge chairs and umbrellas, a beach with umbrellas and lounge chairs, and palm trees.

3. Sundial Beach Resort & Spa

Mid Island

Jeremy

CA $621 total

includes taxes & fees

Dec 10 - Dec 11

A beach with a thatched-roof structure, palm trees, and a view of the sea.

4. The Suites at Fishermen’s Village

Punta Gorda Isles

John

CA $296 total

includes taxes & fees

Nov 30 - Dec 1

A high-rise hotel with multiple floors, a rooftop pool, and a marina in the background.

5. GullWing Beach Resort

South Island

Jennifer

CA $792 total

includes taxes & fees

Dec 2 - Dec 3

A covered outdoor area with a table and chairs, a ceiling fan, and a view of a beach with palm trees and a boat.

6. Island Inn

West End

Nicole

CA $345 total

includes taxes & fees

Nov 12 - Nov 13

A pool area with a waterfall feature, lounge chairs, and palm trees.

7. Tropical Beach Resorts

South Village

Christine

CA $267 total

includes taxes & fees

Nov 12 - Nov 13

A compact kitchen with a built-in seating area, a refrigerator, and a ceiling fan.

8. Matlacha Tiny Village

Matlacha

Shannon

CA $314 total

includes taxes & fees

Nov 15 - Nov 16

A sectional sofa with a chaise, a small table, and a wicker ottoman in an outdoor setting with a clear sky and palm trees.

9. Flamingo Inn

Mid Island

Emily

CA $250 total

includes taxes & fees

Nov 11 - Nov 12

A spacious, multi-level interior with a grand staircase, elegant chandeliers, and a luxurious seating area.

10. Bellasera Resort

Old Naples

vasilisa

CA $541 total

includes taxes & fees

Nov 12 - Nov 13

A balcony with a table and chairs, overlooking a beach with palm trees and a blue building with an American flag.

11. Bridgewalk Resort

Bridge Street

Raisare

CA $501 total

includes taxes & fees

Nov 12 - Nov 13

An outdoor patio with a grill, white chairs, and a red umbrella.

12. Hibiscus Suites - Gateway to Siesta Key

Sarasota

Kat

CA $214 total

includes taxes & fees

Nov 11 - Nov 12

A living room with a view of the ocean, a ceiling fan, and a wooden coffee table.

13. A Beach Retreat

Casey Key

Robin

CA $294 total

includes taxes & fees

Dec 6 - Dec 7

An outdoor dining area with clear plastic chairs and tables, surrounded by greenery and a building in the background.

14. Captiva Beach Resort

South Village

Bob

CA $270 total

includes taxes & fees

Nov 15 - Nov 16

A modern building with a white exterior, a brick gable, and a palm tree in the foreground.

15. Pelican Post at Anna Maria Island Inn

Bradenton Beach

Amylynn

CA $219 total

includes taxes & fees

Dec 9 - Dec 10

A cozy living room with a stone fireplace, a flat-screen TV, a sofa, a coffee table, and a dining area with chairs.

16. The Inn On Siesta Key

Siesta Key

"Thank you Paige & Gabe! My husband & I had a wonderful stay last week in The Nook at your beautiful Inn. Absolutely loved the old Florida charm and perfect location. Your Inn is immaculately kept as well as comfortable. We especially loved our private patio with the fire pit at The Nook. The location of The Inn could not be more perfect being less than a 5 minute walk across the street to Siesta Key beach as well as a short 10 minute walk to town with all the restaurants & shops. Thanks again...

Karen Jean

An indoor pool area with a glass floor, seating around the pool, and a bar area with a blue ceiling and hanging lights.

17. Park Shore Resort

Park Shore

nathaly

CA $522 total

includes taxes & fees

Dec 5 - Dec 6

A modern kitchen with a dining area, featuring a large glass table set for four, a ceiling fan, and a wall clock.

18. Private Pool! Game Room! Very Close to Downtown!

Hancock

CA $766 total

includes taxes & fees

Nov 11 - Nov 12

An aerial view of a resort with multiple blue-roofed buildings, a central swimming pool, and a beach in the background.

19. Sanibel Island - Walk to Beach - Colony Inn 05

East End

Michele W.

CA $682 total

includes taxes & fees

Nov 19 - Nov 20

A room with a dining table, chairs, a TV, and a sliding glass door leading to an outdoor area with a wooden fence and palm trees.

20. Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

East End

Stephen

CA $418 total

includes taxes & fees

Nov 22 - Nov 23

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Find vacation rentals that suit your style

Top Southwest Coast Florida Hotel Reviews

A hotel pool area with lounge chairs and a covered seating area.

Carlisle Inn

Pinecraft

10/10 Excellent

Hôtel est d'une propreté exceptionnelle, tout est propre lobby, ascenseur,passage, les chambres ainsi que la terrasse et piscine extérieur. Un des Hôtel les plus propre que j'ai fréquenté ! Les deux seuls petits points négatifs pour moi, le déjeuner est " basics " comme a bien des endroits d'ailleurs mais par contre la salle a manger est super propre et j'ai trouvé le matelas un peu mou a mon goûts mais certain vont adoré. À recommandé sans hésiter !

Gilbert

A spacious indoor atrium with a high ceiling, featuring a modern building with large windows, surrounded by lush greenery and seating areas.

Innovation Hotel

Naples

10/10 Excellent

Nick

A modern dining area with wicker furniture and a glass partition wall.

Hampton Inn & Suites Naples South

East Naples

10/10 Excellent

Serge

A hotel with a palm tree entrance, a neon sign, and a tiled roof.

Inn at the Beach

Venice Island

10/10 Excellent

Cheryl

A Drury Inn & Suites hotel with a parking lot full of cars.

Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

10/10 Excellent

Billie-Joe

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

Comfort Suites Fort Myers East I-75

Fort Myers

10/10 Excellent

Glenn

A reception area with a modern design, featuring a reception desk, a wall-mounted information board, and a refrigerator stocked with beverages.

MainStay Suites Fort Myers East I-75

Fort Myers

10/10 Excellent

Shaun

A swimming pool with a tiled edge, surrounded by palm trees and a red umbrella.

Home2 Suites Naples I-75 Pine Ridge Road, FL

Naples

10/10 Excellent

Ofelia

A modern hotel lobby with a reception desk, seating area, and a dining section.

Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

10/10 Excellent

Julio Cesar Gutierrez

An outdoor patio with a barbecue area, seating, and string lights.

Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

10/10 Excellent

Kim

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

10/10 Excellent

We had a wonderful stay at Holiday Inn Express Cape Coral. The hotel was very clean, comfortable, and well maintained. A special thank you to Molly at the front desk. She was incredibly friendly, welcoming, and helpful from the moment we arrived. She made us feel truly valued as guests. We would also like to recognize the wonderful lady working in the breakfast area. She kept everything clean, fresh, and well organized, and she was always kind and attentive. The breakfast was excellent, and her...

Isaura

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

10/10 Excellent

Lukasz

A building entrance with a stone facade, a bench, and a water feature.

Holiday Inn Express & Suites Punta Gorda by IHG

Punta Gorda

10/10 Excellent

Front desk staff were very friendly and helpful. The breakfast attendant ladies were amazing - brought food out to our table and were very chatty and lovely. I think their names were Brianna and Uni? Breakfast was terrific: biscuits, gravy, scrambled eggs, bacon sausages, hash browns, cinnamon buns, yogurt, fresh fruit (apples bananas), variety of juices, coffee, milk and almond milk. The pancake machine was the only thing that was iffy - very lightly cooked them so they were still doughy (we...

Catherine

A resort pool area with a large pool, lounge chairs, umbrellas, and a water slide.

Great Wolf Lodge Naples

Rural Estates

10/10 Excellent

We were visiting from canada with our small children (nearly 2 and 4) and we had an amazing time together. The room was lovely (the seperate area for the kids was so cute and perfect for them). We really enjoyed the Waterpark! I didnt know there was no lap riding on the slides though so our youngest couldnt go down any - but she did enjoy the wave pool, lazy river, the many water tables and fountains! The show in the evening with interactive moment like snow falling was so sweet - lots of food...

jacquline

An outdoor patio with wicker furniture, a grill, and lush tropical plants.

Coral Pointe Sarasota, an Ascend Collection Hotel

Fruitville

10/10 Excellent

Milagrosa

A large swimming pool surrounded by lounge chairs and palm trees, with a hotel building in the background.

Sunsuites Villas At Sunseeker Resort, Curio By Hilton

Charlotte Harbor

8/10 Good

Craig

Find out more about Southwest Coast Florida

Everything you need to know about Southwest Coast Florida vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southwest Coast Florida vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southwest Coast Florida vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Southwest Coast Florida vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southwest Coast Florida. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Southwest Coast Florida vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Southwest Coast Florida vacation rentals we have selected for you start as low as CA $100 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Southwest Coast Florida rentals

At Expedia, we put the best Southwest Coast Florida vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southwest Coast Florida rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southwest Coast Florida vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southwest Coast Florida. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Southwest Coast Florida Vacation Rentals

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Southwest Coast Florida vacation rentals

1. StudioRes by Marriott Fort Myers Airport

2. Edison Beach House

3. Sundial Beach Resort & Spa

4. The Suites at Fishermen’s Village

5. GullWing Beach Resort

6. Island Inn

7. Tropical Beach Resorts

8. Matlacha Tiny Village

9. Flamingo Inn

10. Bellasera Resort

11. Bridgewalk Resort

12. Hibiscus Suites - Gateway to Siesta Key

13. A Beach Retreat

14. Captiva Beach Resort

15. Pelican Post at Anna Maria Island Inn

16. The Inn On Siesta Key

17. Park Shore Resort

18. Private Pool! Game Room! Very Close to Downtown!

19. Sanibel Island - Walk to Beach - Colony Inn 05

20. Newly remodeled Parrot Nest Toucan Cottage! Walk to beach, shops, restaurants!

Find vacation rentals that suit your style

Top Southwest Coast Florida Hotel Reviews

Carlisle Inn

10/10 Excellent

Find out more about Southwest Coast Florida

Southwest Coast Florida vacation rentals: An excellent choice for every season

How to find incredible deals on Southwest Coast Florida rentals

Explore a world of travel with Expedia