Title: Book the Best Southeastern Indiana SPA Resorts from CA $125 - Spa Hotels in Southeastern Indiana | Expedia.ca

[Southeastern Indiana Travel Guide](https://expedia.ca/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.ca/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.ca/Southeastern-Indiana.d6233889.Destination-Travel-Guides)

![Bathe in the forest...find this on the roof of the outdoor shower house down the hill from the guest house.](https://images.trvl-media.com/place/553248635989202622/88a60920-d501-4b4d-b386-caf78a7f4191.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Serendipity Trip

# Find Spa Hotels in Southeastern Indiana from CA $125

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## Check availability on Southeastern Indiana Spa Hotels

Tonight

[Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-12&endDate=2025-12-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 13 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-13&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-12&endDate=2025-12-14&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-12-19&endDate=2025-12-21&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southeastern Indiana hotels with a spa

![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/162eb275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Golf](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/7f00b921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/2ac61b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Belterra Casino Resort

[](https://www.expedia.ca/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information)

Florence

8.6/10

Excellent

(1002)

"Room was clean and the staff was good."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gary

CA $144

CA $178 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/e725185b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/ab0af7cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9c82234b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(3851)

"Beautiful room and great hospitality. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chase

CA $184

CA $216 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/06213b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1002)

"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

CA $191

CA $232 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/a36c57b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/bea44cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Caesars Southern Indiana - A Caesars Rewards Destination

[](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information)

Elizabeth

8.2/10

Very good

(1002)

"The room was very clean, the staff was very friendly and helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy

CA $274

CA $332 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information)

![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1727)

"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Bonnie

CA $230

CA $271 total

includes taxes & fees

Jan 1 - Jan 2, 2026

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/eec2d0c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

CA $200

CA $301 total

includes taxes & fees

Jan 4 - Jan 5, 2026

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/95d9177a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/787112cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/1e2d6baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/94b6bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Central Park Bed & Breakfast

[](https://www.expedia.ca/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information)

Old Louisville

9.4/10

Exceptional

(57)

"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

CA $174

CA $203 total

includes taxes & fees

Dec 17 - Dec 18

[](https://www.expedia.ca/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/a62748ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/d25d1009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/1ea5b0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/914ff829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Seymour I-65

[](https://www.expedia.ca/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information)

Seymour

7.0/10

Good

(561)

"Had a room on first floor close to breakfast and desk."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Karlyn

CA $111

CA $125 total

includes taxes & fees

Jan 10 - Jan 11, 2026

[](https://www.expedia.ca/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/40c412dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/e77d0e77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/82066f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Multiple Beds, Pets Allowed, Garden View | Living area](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pillow and Paddock B&B

[](https://www.expedia.ca/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information)

La Grange

10/10

Exceptional

(51)

"Great stay. Great hospitality"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James

CA $438

CA $483 total

includes taxes & fees

Dec 15 - Dec 16

[](https://www.expedia.ca/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-26&endDate=2025-12-27&regionId=6233889&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true)

## Top Southeastern Indiana Hotel Reviews

![Ramada by Wyndham Sellersburg/Louisville North](https://images.trvl-media.com/lodging/1000000/660000/659000/658960/dbc92ac1_y.jpg)

### Ramada by Wyndham Sellersburg/Louisville North

10/10 Excellent

"Clean room, helpful staff, good breakfast "

[](https://expedia.ca/Sellersburg-Hotels-Ramada-By-Wyndham-SellersburgLouisville-North.h658960.Hotel-Information)

![Hampton Inn New Albany Louisville West](https://images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg)

### Hampton Inn New Albany Louisville West

10/10 Excellent

"Stay was perfect! Friendly staff, very clean "

[](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information)

![Big Splash Adventure Indoor Water Park & Resort](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857069/63744e7b_y.jpg)

### Big Splash Adventure Indoor Water Park & Resort

10/10 Excellent

"👍"

[](https://expedia.ca/French-Lick-Hotels-Big-Splash-Adventure-Indoor-Water-Park-Resort.h4857069.Hotel-Information)

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- [Kentucky Lake ](https://www.expedia.ca/Kentucky-Lake-United-States-of-America.d6059618.Vacation-Attraction)
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- [Advantage Rent-A-Car Rental Cars in Ohio River Valley ](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Ohio-River-Valley.d6233674-c3.Car-Rental-Guide-Suppliers)
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- [Things to do in Southern Indiana ](https://www.expedia.ca/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities)

- [Book Spa Hotels in Southeastern Indiana on Expedia.com ](https://www.expedia.com/Southeastern-Indiana-Hotels-Spa-Hotel.0-0-d6233889-tSpaHotel.Travel-Guide-Filter-Hotels)