Title: Southeast Missouri B&B: Find the Best Bed and Breakfast | Expedia.ca [Southeast Missouri Travel Guide](https://expedia.ca/Southeast-Missouri.dx6058763)[Hotels in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[Vacation Rentals in Southeast Missouri](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[Flights to Southeast Missouri](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[Things to do in Southeast Missouri](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities)[Southeast Missouri Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[Southeast Missouri Vacation Packages](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/9/6538ce9b088c58039b33a5fe701e7a1f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find a Bed and Breakfast in Southeast Missouri ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-17&endDate=2025-10-19&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-11-07&endDate=2025-11-09&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=6058763&startDate=2025-12-05&endDate=2025-12-07&adults=2&lodging=BED_AND_BREAKFAST&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Southeast Missouri B&B ![Shared kitchen](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/66a0aee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/7cff82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Penthouse, Multiple Beds | Living area](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/3d2bd2be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Patio | Bathroom](https://images.trvl-media.com/lodging/113000000/112370000/112361000/112360980/fd3771f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Academy Arcadia 9.8/10 Exceptional (9) "We really enjoyed our stay. Great food and the staff was the nicest/ friendliest I have ever had the pleasure of meeting. " CA $158 CA $172 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Arcadia-Hotels-Arcadia-Academy.h112360980.Hotel-Information) ![Miscellaneous](https://images.trvl-media.com/lodging/13000000/12520000/12514000/12513911/a1fd6a1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/13000000/12520000/12514000/12513911/2cb15451.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Ensuite (Alaska)](https://images.trvl-media.com/lodging/13000000/12520000/12514000/12513911/7f33d300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12520000/12514000/12513911/77e6e6a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Grant's Trail St. Louis 9.6/10 Exceptional (456) "Amazing stay!" CA $194 CA $224 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/St-Louis-Hotels-The-Lodge-At-Grants-Trail.h12513911.Hotel-Information) ![Gift shop](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/c29b94f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roever Room](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/b0233202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![McRoberts Room](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/f44f88b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft Suite](https://images.trvl-media.com/lodging/7000000/6060000/6058000/6057984/bfc4ab94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Corner George Inn Bed & Breakfast Maeystown 9.0/10 Wonderful (153) "Hosts were excellent, very quiet and the breakfast was wonderful" CA $166 CA $185 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Maeystown-Hotels-Corner-George-Inn-Bed-Breakfast.h6057984.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/d6ab8f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/f6b73146.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage, Multiple Beds, Non Smoking (West End Cottage)](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/a07ef7d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast (USD 15 per person)](https://images.trvl-media.com/lodging/35000000/34530000/34529000/34528901/2b5c2eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Makanda Inn Makanda 10/10 Exceptional (33) "Big thank you to the team at the cabin! Great people, great service, and great food! " CA $375 CA $428 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Carbondale-Hotels-Makanda-Inn-Cottages.h34528901.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6058763&adults=2&lodging=BED_AND_BREAKFAST&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Bed-And-Breakfast.d6058763-aaBedAndBreakfast.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSoutheast-Missouri-Bed-And-Breakfast.d6058763-aaBedAndBreakfast.Travel-Guide-Accommodation) ## Top Southeast Missouri Hotel Reviews ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "Clean room. " [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Motel 6 Poplar Bluff, MO](//images.trvl-media.com/lodging/16000000/15690000/15689200/15689127/9e93b298_y.jpg) ### Motel 6 Poplar Bluff, MO 10/10 Excellent "Property was very clean, staff wa very friendly. And room was perfect!" [](https://expedia.ca/Poplar-Bluff-Hotels-Motel-6-Poplar-Bluff.h15689127.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](//images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Clean" [](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Newer hotel so clean. Walk-in shower with no door but works. Control is on opposite side of shower head so alittle awkward. Starbucks was nice. Front desk very accommodating. Close to old downtown but too far to walk. Railroad tracks on east side but didn’t reallly hear. " [](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Baymont Inn and Suites by Wyndham Farmington, MO](//images.trvl-media.com/lodging/1000000/20000/16200/16153/02759b26_y.jpg) ### Baymont Inn and Suites by Wyndham Farmington, MO 10/10 Excellent "It was very nice. There was a problem with me being charge 2 times but that was fix right away" [](https://expedia.ca/Farmington-Hotels-Baymont-Inn-And-Suites-By-Wyndham-Farmington.h16153.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](//images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "Clean, well maintained." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "The lady that checked me in was amazing!" [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Love to stay at any Drury. They do things right. Most friendly guest service staff around." [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Quality Inn](//images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg) ### Quality Inn 10/10 Excellent "It was fine " [](https://expedia.ca/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ## Find out more about Southeast Missouri ## Southeast Missouri B&B information | Number of reviews | | | --- | --- | | Accommodation | B&B | | Lowest Price | | | Highest Price | | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [B&B in Annapolis](https://www.expedia.ca/Annapolis-Bed-And-Breakfast.d6282465-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with Balconies in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Hotels-With-Balconies.0-0-d6282465-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Annapolis](https://www.expedia.ca/Annapolis-Hotels-Luxury-Hotel.0-0-d6282465-tLuxuryHotel.Travel-Guide-Filter-Hotels) - 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