Panoramic view from Mesa Trail overlooking Santee, with dry hills and distant mountains under a clear sky

Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,120 reviews)
"Great stay! Big room, comfortable"
United States
Christine
The price is CA $278
CA $322 total
includes taxes & fees
Jul 19 - Jul 20
Marriott Vacation Club®, San Diego

Coronado Beach Resort

Coronado Beach Resort
3.0 star property
Historic Downtown Coronado
9.0 out of 10, Wonderful, (799 reviews)
"Great stay"
United States
Vjosa
The price is CA $540
CA $593 total
includes taxes & fees
Jul 26 - Jul 27
Coronado Beach Resort

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (166 reviews)
"Nice and very friendly staff was a great stay"
United States
Alexander
The price is CA $201
CA $275 total
includes taxes & fees
Jul 2 - Jul 3
City24 Hotel Little Italy Mission Hills

Yard & Grill! Cottage Near Balboa Park & Comic-con

Yard & Grill! Cottage Near Balboa Park & Comic-con
3.0 star property
South Park
The price is CA $299
CA $720 total
includes taxes & fees
Jul 1 - Jul 2
Yard & Grill! Cottage Near Balboa Park & Comic-con

Hilltop cabin with panoramic lake & mountain views

Hilltop cabin with panoramic lake & mountain views
Del Dios
9.6 out of 10, Exceptional, (39 reviews)
"I loved how unique and cute this stay was"
United States
Kayla
The price is CA $188
CA $281 total
includes taxes & fees
Jul 1 - Jul 2
Hilltop cabin with panoramic lake & mountain views

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (96 reviews)
"Amazing stay overall!"
United States
Imany G.
The price is CA $356
CA $451 total
includes taxes & fees
Jun 28 - Jun 29
Beautiful Normal Heights Living

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (54 reviews)
"Everything was in great shape."
United States
emma c.
The price is CA $243
CA $418 total
includes taxes & fees
Jul 1 - Jul 2
Adorable 1 bedroom house 8 min from La Jolla!

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance
Pacific Beach
9.6 out of 10, Exceptional, (54 reviews)
"Second stay and we’ll be back !! Good location, owner easy to work with, clean & tidy !!"
United States
Kevin O.
The price is CA $283
CA $495 total
includes taxes & fees
Jul 12 - Jul 13
Cozy Pacific Beach Cottage w/Bikes, Private Yard & Entrance

Bright and spacious home with views, pool & spa.

Bright and spacious home with views, pool & spa.
San Carlos
9.4 out of 10, Exceptional, (30 reviews)
"Everything was as advertised, I would recommend staying here."
United States
Scott S.
The price is CA $689
CA $1,186 total
includes taxes & fees
Jun 28 - Jun 29
Bright and spacious home with views, pool & spa.

Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground

Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground
Mount Helix
10.0 out of 10, Exceptional, (35 reviews)
"Fully stocked house, great commutation "
United States
Jim F.
The price is CA $1,252
CA $2,619 total
includes taxes & fees
Jul 1 - Jul 2
Luxury Private Oasis- 2 King Suites - Pool-Spa-Fire Pit-Sauna-Arcades-Playground

Private Cozy Clean, close to EVERYTHING

Private Cozy Clean, close to EVERYTHING
Mid-City
9.8 out of 10, Exceptional, (67 reviews)
"Everything was great, convenient location to everything. "
United States
Terri J.
The price is CA $407
CA $784 total
includes taxes & fees
Jul 26 - Jul 27
Private Cozy Clean, close to EVERYTHING

Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi

Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi
Beach Barber Tract
9.8 out of 10, Exceptional, (17 reviews)
"Can’t beat the location! Property felt “new” - almost like we were the first to stay there. Good communication from property manager. Would return the next time we visit San Diego."
United States
Kevin
The price is CA $602
CA $932 total
includes taxes & fees
Jun 29 - Jun 30
Luxe 2BR La Jolla Escape Near the Beach & Jacuzzi

Stylish South Park Home | Near Zoo, Downtown & Dining

Stylish South Park Home | Near Zoo, Downtown & Dining
Mid-City
10.0 out of 10, Exceptional, (15 reviews)
"Wonderful spot to stay. Perfect distance from popular San Diego attractions, and the interior was tidy and comfortable."
United States
Aidan N.
The price is CA $730
CA $1,309 total
includes taxes & fees
Jun 28 - Jun 29
Stylish South Park Home | Near Zoo, Downtown & Dining

Near Pacific Beach, Comic-con! Sunny San Diego Gem

Near Pacific Beach, Comic-con! Sunny San Diego Gem
3.0 star property
Pacific Beach
10.0 out of 10, Exceptional, (2 reviews)
"Strategic location for beach, amusement parks and restaurants. Close to major freeways and airport. House has plenty of room across the three floors. Kids loved seeing the seaworld fireworks from the open air rooftop patio. This property has it all. Owner quickly addressed any of our questions and needs. "
United States
Thomas
The price is CA $957
CA $1,658 total
includes taxes & fees
Jul 2 - Jul 3
Near Pacific Beach, Comic-con! Sunny San Diego Gem

Family Friendly Modern Guest House

Family Friendly Modern Guest House
Mira Mesa
10.0 out of 10, Exceptional, (16 reviews)
"Very nice and comfortable home. June was very attentive and quick to respond to any questions. "
United States
Nancy M.
The price is CA $451
CA $881 total
includes taxes & fees
Jul 13 - Jul 14
Family Friendly Modern Guest House

Ocean Beach Pier Condo

Ocean Beach Pier Condo
Ocean Beach
9.8 out of 10, Exceptional, (64 reviews)
"Really like the place and so did my family!! Great location!! Would recommend this place!! "
United States
Brittany B.
The price is CA $540
CA $929 total
includes taxes & fees
Jul 20 - Jul 21
Ocean Beach Pier Condo

Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!

Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!
Ocean Beach
10.0 out of 10, Exceptional, (273 reviews)
"Great location, very clean. Easy beach access. It was perfect for our family. Very relaxing. We appreciated the beach accessories. "
United States
Jenny R.
The price is CA $361
CA $803 total
includes taxes & fees
Jun 29 - Jun 30
Perfect Location to Beach/SD Attractions, Parking, Beach Chairs, Boogie Boards!

San Diego’s Luxury Mountain Cabin Retreat

San Diego’s Luxury Mountain Cabin Retreat
El Cajon
9.8 out of 10, Exceptional, (22 reviews)
"We had a wonderful stay! The house was great and exactly as shown in the listing—the pictures and description were 100% accurate. Communication with the host was excellent; they were very responsive and helpful throughout the entire process. Highly recommend this property!"
United States
Claudia M.
The price is CA $796
CA $1,525 total
includes taxes & fees
Jul 11 - Jul 12
San Diego’s Luxury Mountain Cabin Retreat

Near Pacific Beach, Comic-Con! Sunny San Diego Gem

Near Pacific Beach, Comic-Con! Sunny San Diego Gem
Pacific Beach
9.6 out of 10, Exceptional, (63 reviews)
"Love the rooftop patioGreat location Always clean and comfortable "
United States
Rene O.
Near Pacific Beach, Comic-Con! Sunny San Diego Gem

La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (7 reviews)
"The property was well located for us. "
United States
Ann D.
The price is CA $483
CA $1,039 total
includes taxes & fees
Jul 7 - Jul 8
La Mesa Family Retreat - 20 minutes to Beaches & More!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: You might want to consider this vacation rental near Santee, which is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 6 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Sportsplex USA Santee and Santee Lakes are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Petco Park are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.