Title: Book the Best Santee GAY-FRIENDLY Hotels in 2025 | Expedia.ca [Santee Travel Guide](https://expedia.ca/Santee.dx9953)[Hotels in Santee](https://expedia.ca/Santee-Hotels.d9953.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.ca/Santee-Vacation-Rentals.d9953.Travel-Guide-VacationRentals)[Flights to Santee](https://expedia.ca/Cheap-Flights-To-Santee.d9953.Travel-Guide-Flights)[Santee Car Rentals](https://expedia.ca/Car-Rentals-In-Santee.d9953.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.ca/Santee.d9953.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/271db9a9db85f6f3488271b71d2f238f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Find LGBTQ welcoming hotels in Santee, SC ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Santee LGBT Friendly Hotels ![Fairfield Inn & Suites by Marriott Santee](https://images.trvl-media.com/lodging/1000000/30000/26200/26116/dfe24eeb_y.jpg?impolicy=resizecrop&rw=340&ch=150) [Fairfield Inn & Suites by Marriott Santee](https://expedia.ca/Orangeburg-Hotels-Fairfield-Inn-Suites-By-Marriott-Santee.h26116.Hotel-Information) 9074 Old Number Six Hwy, Santee, SC Fully refundableReserve now, pay when you stay CA $167 CA $185 total Sep 24 - Sep 25 includes taxes & fees 9.8/10 Exceptional! (1,001 reviews) "Amazing staff - friendly and courteous - good breakfast too!!" Reviewed on Sep 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=24%2F09%2F2025&endDate=25%2F09%2F2025&selected=26116&PinnedHotelID=26116&HadPinnedHotel=true®ionId=9953&travelerType=LGBT) ![Hampton Inn Santee-I-95](https://images.trvl-media.com/lodging/1000000/210000/203700/203667/5f0a1276_y.jpg?impolicy=resizecrop&rw=340&ch=150) [Hampton Inn Santee-I-95](https://expedia.ca/Orangeburg-Hotels-Hampton-Inn-Santee-I-95.h203667.Hotel-Information) 9060 Old Number Six Hwy, Santee, SC Fully refundableReserve now, pay when you stay CA $170 CA $189 total Sep 24 - Sep 25 includes taxes & fees 9.6/10 Exceptional! (1,002 reviews) "Quiet, big room for King, free parking" Reviewed on Sep 10, 2025 [](https://expedia.ca/Hotel-Search?startDate=24%2F09%2F2025&endDate=25%2F09%2F2025&selected=203667&PinnedHotelID=203667&HadPinnedHotel=true®ionId=9953&travelerType=LGBT) ![Holiday Inn Santee by IHG](https://images.trvl-media.com/lodging/2000000/1220000/1220000/1219924/c82722a1_y.jpg?impolicy=resizecrop&rw=340&ch=150) [Holiday Inn Santee by IHG](https://expedia.ca/Orangeburg-Hotels-Holiday-Inn-Santee.h1219924.Hotel-Information) 139 Bradford Blvd, Santee, SC Fully refundable CA $175 CA $194 total Oct 19 - Oct 20 includes taxes & fees 8/10 Very Good! (944 reviews) "Easy, convenient, clesn" Reviewed on Sep 16, 2025 [](https://expedia.ca/Hotel-Search?startDate=19%2F10%2F2025&endDate=20%2F10%2F2025&selected=1219924&PinnedHotelID=1219924&HadPinnedHotel=true®ionId=9953&travelerType=LGBT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-LGBT-Friendly-Hotel.0-0-d9953-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Hotels-LGBT-Friendly-Hotel.0-0-d9953-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![Red Roof Inn Santee](https://images.trvl-media.com/lodging/1000000/860000/856700/856695/4686cd8f_y.jpg?impolicy=resizecrop&rw=340&ch=150) [Red Roof Inn Santee](https://expedia.ca/Orangeburg-Hotels-Red-Roof-Inn-Santee.h856695.Hotel-Information) 9091 Old Hwy 6, Santee, SC Fully refundableReserve now, pay when you stay CA $101 CA $112 total Sep 21 - Sep 22 includes taxes & fees 6.4/10 (625 reviews) "Despite offering breakfast, it was lackluster" Reviewed on Aug 23, 2025 [](https://expedia.ca/Hotel-Search?startDate=21%2F09%2F2025&endDate=22%2F09%2F2025&selected=856695&PinnedHotelID=856695&HadPinnedHotel=true®ionId=9953&travelerType=LGBT) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [See all LGBTQ welcoming stays in Santee](https://expedia.ca/Hotel-Search?regionId=9953&propertyStyle=LGBT&travelerType=LGBT) ## Find the top gay-friendly hotels in Santee #### Are gay-friendly hotels in Santee available? Yes, Santee gay-friendly hotels are available in abundance throughout the area. These hotels come in a wide variety of configurations as well, allowing you to customize your vacation whether you're looking for something budget-friendly or something more luxurious. Room configurations, amenities, styles and more can all be customized as you see fit based on the kind of vacation experience you're looking for. Plus, these hotels have strict policies against discrimination and typically are in the know regarding the best LGBTQ-friendly activities in town. #### How can I find the best gay-friendly hotels in Santee? Finding Santee gay-friendly hotels is easy, thanks to our search filters. You'll find a massive array of filters, so you can sort your results to only show hotels that cater specifically to your desired vacation experience. You can implement filters for amenities in your hotel as well as for star ratings and guest reviews. You'll even find filters for price, so you can limit your results to only show hotels that are within your established budget. Additionally, you'll find a filter for LGBTQ-friendly hotels, so be sure to activate that one to sort all the non-accommodating hotels out of your search results. #### How can I find top deals on gay-friendly hotels in Santee? To find deals, you'll want to take advantage of the various factors that affect hotel prices. These include the time of year, amenities, neighbourhood and more. Travelling during the off-season can net you lower prices, as can relinquishing amenities like spas and hot tubs. Additionally, booking outside of town can be cheaper than putting yourself right in the middle of the action. Don't forget to sort your search results by price as well to see the cheapest options for your hotel first. Gay-friendly hotels in Santee have fluctuating prices, so it's important to remember that these are more general trends than rules set in stone. #### Why should I book Santee gay-friendly hotels with Expedia? Booking with Expedia is among the easiest ways to ensure all your travel planning can be taken care of in a single, convenient place. Not only will you find an array of gay-friendly hotels in Santee to choose from, but you'll find flights as well. The extensive search filters make finding the ultimate accommodation simple, as you can narrow down your search results to show only the hotels that fit your strict specifications. Plus, you can enjoy the Expedia Rewards program, which lets you earn points every time you book. Those points can be redeemed for discounts on future bookings, but that's just the beginning. Some accommodation options have special discounts only available to members. Becoming a member is free, so don't hesitate to take advantage. ## LGBTQ-welcoming hotels in top travel spots ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Montreal_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Montreal [](https://expedia.ca/Hotel-Search?regionId=178288&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Palm_Springs_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Palm Springs [](https://expedia.ca/Hotel-Search?regionId=180676&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Puerto_Vallerta_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Puerto Vallarta [](https://expedia.ca/Hotel-Search?regionId=180016&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Key_West_Florida_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Key West [](https://expedia.ca/Hotel-Search?regionId=1187&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Miami_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Miami [](https://expedia.ca/Hotel-Search?regionId=8833&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Cancun_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Cancun [](https://expedia.ca/Hotel-Search?regionId=179995&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Paris_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Paris [](https://expedia.ca/Hotel-Search?regionId=179898&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Amsterdam_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Amsterdam [](https://expedia.ca/Hotel-Search?regionId=178229&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Barcelona_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Barcelona [](https://expedia.ca/Hotel-Search?regionId=179992&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_London_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### London [](https://expedia.ca/Hotel-Search?regionId=178279&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_NYC_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### New York [](https://expedia.ca/Hotel-Search?regionId=178293&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_San_Francisco_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### San Francisco [](https://expedia.ca/Hotel-Search?regionId=178305&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_Chicago_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Chicago [](https://expedia.ca/Hotel-Search?regionId=178248&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ![](https://forever.travel-assets.com/flex/flexmanager/images/2021/02/17/ORB_LA_c.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) ### Los Angeles [](https://expedia.ca/Hotel-Search?regionId=178280&rfrr=HTG.LGBTQ.Tile&travelerType=LGBT) ## Explore a world of travel with Expedia - 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