Title: South Carolina LGBT Friendly Hotels from CA $644: Book the Right LGBT Friendly Hotels Room in South Carolina, United States of America - Expedia.ca [South Carolina Travel Guide](https://expedia.ca/South-Carolina.dx242)[South Carolina Hotels](https://expedia.ca/Destinations-In-South-Carolina.d242.Hotel-Destinations)[Vacation Rentals in South Carolina](https://expedia.ca/Destinations-In-South-Carolina.d242.Vacation-Rental-Destinations)[South Carolina Flights](https://expedia.ca/Destinations-In-South-Carolina.d242.Flight-Destinations)[South Carolina Car Rentals](https://expedia.ca/Destinations-In-South-Carolina.d242.Car-Rental-Destinations)[South Carolina Vacations](https://expedia.ca/South-Carolina.d242.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/242/dbb303b5-35ae-4057-85af-2d617c5d6007.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in South Carolina ![Greenville featuring a city, a bridge and a river or creek](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63754-Greenville-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Greenville [](https://expedia.ca/Greenville-Hotels-LGBT-Friendly-Hotel.0-0-d1388-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/553000/553975-charleston-sc.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Charleston [](https://expedia.ca/Charleston-Hotels-LGBT-Friendly-Hotel.0-0-d179997-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/494000/494078-myrtle-beach.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Myrtle Beach [](https://expedia.ca/Myrtle-Beach-Hotels-LGBT-Friendly-Hotel.0-0-d601685-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![South Carolina State House](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/184000/184006-State-House.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Columbia [](https://expedia.ca/Columbia-Hotels-LGBT-Friendly-Hotel.0-0-d764-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![Hilton Head featuring general coastal views and a sandy beach as well as an individual female](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/33000/33732-Hilton-Head.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Hilton Head Island [](https://expedia.ca/Hilton-Head-Island-Hotels-LGBT-Friendly-Hotel.0-0-d601684-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/493000/493363-coastal-south-carolina.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### North Myrtle Beach [](https://expedia.ca/North-Myrtle-Beach-Hotels-LGBT-Friendly-Hotel.0-0-d8929-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![USS Yorktown which includes aircraft](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/30000/30538-Uss-Yorktown.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Mount Pleasant [](https://expedia.ca/Mount-Pleasant-Hotels-LGBT-Friendly-Hotel.0-0-d8675-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![Spartanburg showing a house, farmland and land animals](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/63000/63879-Spartanburg.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Spartanburg [](https://expedia.ca/Spartanburg-Hotels-LGBT-Friendly-Hotel.0-0-d9787-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![](https://mediaim.expedia.com/destination/1/02bc21c256f396c5f15b8a28c58632c0.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### North Charleston [](https://expedia.ca/North-Charleston-Hotels-LGBT-Friendly-Hotel.0-0-d9156-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on South Carolina LGBT Friendly Hotels Tonight [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=242&startDate=2026-01-16&endDate=2026-01-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=242&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=242&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=242&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ## Our top choices for South Carolina LGBT-friendly hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/8bc9a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/9b424641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/63d8939c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/1000000/30000/28600/28504/b023ad91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Charleston Place [](https://www.expedia.ca/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) Charleston Historic District 9.6/10 Exceptional (1,002 reviews) "Very nice , helpful and friendly staff, great location. Great ambiance for family vacation. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nazanin CA $506 CA $644 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Charleston-Hotels-Charleston-Place.h28504.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=242&adults=2&travelerType=lgbtq_welcoming&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-LGBT-Friendly-Hotel.0-0-d242-tLGBTFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-South-Carolina-LGBT-Friendly-Hotel.0-0-d242-tLGBTFriendlyHotel.Hotel-Filter-Destinations) ## Top South Carolina Hotel Reviews ![Emeline](https://images.trvl-media.com/lodging/1000000/10000/8900/8890/d17025e1_y.jpg) ### Emeline 10/10 Excellent "Beautiful spot with tons of unique details " [](https://expedia.ca/Charleston-Hotels-Emeline.h8890.Hotel-Information) ![Homewood Suites by Hilton Greenville Downtown](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2_y.jpg) ### Homewood Suites by Hilton Greenville Downtown 10/10 Excellent "Very nice" [](https://expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![The Ryder Hotel](https://images.trvl-media.com/lodging/1000000/10000/4600/4544/722c7929_y.jpg) ### The Ryder Hotel 10/10 Excellent "Hotel was clean & staff friendly. Great coffee shop and location was perfect to walk everywhere. " [](https://expedia.ca/Charleston-Hotels-The-Ryder-Hotel.h4544.Hotel-Information) ![Planters Inn](https://images.trvl-media.com/lodging/1000000/10000/4800/4769/c138e1de_y.jpg) ### Planters Inn 10/10 Excellent "Staff were amazing. " [](https://expedia.ca/Charleston-Hotels-Planters-Inn.h4769.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Convenient and clean" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Hotel Indigo Mount Pleasant by IHG](https://images.trvl-media.com/lodging/1000000/10000/8300/8255/95dbd824_y.jpg) ### Hotel Indigo Mount Pleasant by IHG 10/10 Excellent "Loved the heated pool and outdoor area. Great food options. Beautiful property. Clean rooms " [](https://expedia.ca/Charleston-Hotels-Hotel-Indigo-Mount-Pleasant.h8255.Hotel-Information) ![Coral Beach Resort and Suites](https://images.trvl-media.com/lodging/1000000/40000/37100/37007/92701cca_y.jpg) ### Coral Beach Resort and Suites 10/10 Excellent "Nice place to stay. Quite a ways from the boardwalk but otherwise enjoyable!" [](https://expedia.ca/Myrtle-Beach-Hotels-Coral-Beach-Resort-Hotel-Suites.h37007.Hotel-Information) ![Holiday Inn Express Hilton Head Island by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1341/e21613a3_y.jpg) ### Holiday Inn Express Hilton Head Island by IHG 10/10 Excellent "Great customer service beginning at check in" [](https://expedia.ca/Hilton-Head-Hotels-Holiday-Inn-Express-Hilton-Head-Island.h1341.Hotel-Information) ![Hilton Grand Vacations Club Ocean Enclave Myrtle Beach](https://images.trvl-media.com/lodging/34000000/33220000/33213200/33213151/d233caaf_y.jpg) ### Hilton Grand Vacations Club Ocean Enclave Myrtle Beach 10/10 Excellent "Clean room" [](https://expedia.ca/Myrtle-Beach-Hotels-Ocean-Enclave-By-Hilton-Grand-Vacations.h33213151.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [5 Star Hotels in Columbia ](https://www.expedia.ca/5Star-Columbia-Hotels.s50-0-d764.Travel-Guide-Filter-Hotels) - 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