Title: Santa Fe de Antioquia Vacation Rentals from CA $66: Short-Term Rentals for 2026 | Expedia.ca

[Santa Fe de Antioquia Travel Guide](https://expedia.ca/Santa-Fe-De-Antioquia.dx6143343)[Hotels in Santa Fe de Antioquia](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Flights to Santa Fe de Antioquia](https://expedia.ca/Cheap-Flights-To-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Flights)[Things to do in Santa Fe de Antioquia](https://expedia.ca/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe-De-Antioquia.d6143343.Car-Rental-Guide)[Santa Fe de Antioquia Vacation Packages](https://expedia.ca/Santa-Fe-De-Antioquia.d6143343.Destination-Travel-Guides)

![Pretty little colonial town just less than 2 hours drive from Medellín ](https://images.trvl-media.com/place/6143343/03709660-306c-4598-b888-d638aa186980.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Botak Jon

![](https://images.trvl-media.com/place/6143343/03709660-306c-4598-b888-d638aa186980.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6143343&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6143343&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=6143343&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.ca/Hotel-Search?regionId=6143343&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Fe de Antioquia vacation rentals

![Exterior](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/a546314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/4a67df51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/03d86e13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/120000000/119570000/119565600/119565573/ab281300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Finca hotel mi refugio

[](https://www.expedia.ca/Santa-Fe-De-Antioquia-Hotels-Finca-Hotel-Mi-Refugio.h119565573.Hotel-Information)

Santa Fé de Antioquia

CA $66

CA $66 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Santa-Fe-De-Antioquia-Hotels-Finca-Hotel-Mi-Refugio.h119565573.Hotel-Information)

![6 outdoor pools](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/9b39b471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Pool View | Living area](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/6d76c665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Pool View | Living area](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/538e9e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, Pool View | Living area](https://images.trvl-media.com/lodging/109000000/108750000/108747200/108747191/3a1caae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SANTA FE DE ANTIOQUIA

[](https://www.expedia.ca/Santa-Fe-De-Antioquia-Hotels-SANTA-FE-DE-ANTIOQUIA.h108747191.Hotel-Information)

Santa Fe de Antioquia

8.0/10

Very good

(1 review)

"Todo Ok"

![Costa Rica](https://a.travel-assets.com/egds/marks/flags/cr.svg)

Nohelys

CA $95

CA $119 total

Feb 19 - Feb 20

[](https://www.expedia.ca/Santa-Fe-De-Antioquia-Hotels-SANTA-FE-DE-ANTIOQUIA.h108747191.Hotel-Information)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114360000/114355700/114355636/b02c95f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114360000/114355700/114355636/d9a14114.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114360000/114355700/114355636/326cabd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114360000/114355700/114355636/325903fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Estadio Studio Laurelesjacuzziterrace &fast Wifi

[](https://www.expedia.ca/Medellin-Hotels-Estadio-Studio-Laurelesjacuzziterrace-Fast-Wifi.h114355636.Hotel-Information)

Laureles - Estadio

[](https://www.expedia.ca/Medellin-Hotels-Estadio-Studio-Laurelesjacuzziterrace-Fast-Wifi.h114355636.Hotel-Information)

![Comfort Apartment, Balcony, City View](https://images.trvl-media.com/lodging/124000000/123360000/123351700/123351615/f14fd2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment, Balcony, City View](https://images.trvl-media.com/lodging/124000000/123360000/123351700/123351615/c60a24c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment, Balcony, City View](https://images.trvl-media.com/lodging/124000000/123360000/123351700/123351615/35e0879f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment, Balcony, City View | Private kitchen](https://images.trvl-media.com/lodging/124000000/123360000/123351700/123351615/588593e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Un lugar para soñar 

[](https://www.expedia.ca/Medellin-Hotels-Un-Lugar-Para-Sonar.h123351615.Hotel-Information)

La América

CA $149

CA $149 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Medellin-Hotels-Un-Lugar-Para-Sonar.h123351615.Hotel-Information)

![Apartment, 1 Bedroom, Balcony | Balcony](https://images.trvl-media.com/lodging/120000000/119370000/119365500/119365446/d5a1ceb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Balcony | Room amenity](https://images.trvl-media.com/lodging/120000000/119370000/119365500/119365446/2591dc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Balcony | Pool](https://images.trvl-media.com/lodging/120000000/119370000/119365500/119365446/804033dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/120000000/119370000/119365500/119365446/10b26d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stylish 1BR Getaway, Jacuzzi, Fireplace, Gym and AC

[](https://www.expedia.ca/Medellin-Hotels-Stylish-1BR-Getaway.h119365446.Hotel-Information)

Medellín

CA $103

CA $103 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Medellin-Hotels-Stylish-1BR-Getaway.h119365446.Hotel-Information)

![Luxury Studio](https://images.trvl-media.com/lodging/120000000/119150000/119148700/119148679/8daaadcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Studio](https://images.trvl-media.com/lodging/120000000/119150000/119148700/119148679/fd95a79a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Studio | Living area](https://images.trvl-media.com/lodging/120000000/119150000/119148700/119148679/b76efe07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio](https://images.trvl-media.com/lodging/120000000/119150000/119148700/119148679/e9e40a5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comuna Loft 

[](https://www.expedia.ca/Medellin-Hotels-Comuna-Loft.h119148679.Hotel-Information)

San Javier

[](https://www.expedia.ca/Medellin-Hotels-Comuna-Loft.h119148679.Hotel-Information)

![House](https://images.trvl-media.com/lodging/124000000/123610000/123604700/123604647/10384107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/124000000/123610000/123604700/123604647/c45d1335.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/124000000/123610000/123604700/123604647/w2999h2000x0y0-985393d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House](https://images.trvl-media.com/lodging/124000000/123610000/123604700/123604647/8bdd9ce6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### w Bright Colonial 5BR House With Balcony

[](https://www.expedia.ca/Medellin-Hotels-W-Bright-Colonial-5BR-House-With-Balcony.h123604647.Hotel-Information)

La América

CA $504

CA $504 total

Mar 4 - Mar 5

[](https://www.expedia.ca/Medellin-Hotels-W-Bright-Colonial-5BR-House-With-Balcony.h123604647.Hotel-Information)

![Compostela 302 | Living area](https://images.trvl-media.com/lodging/103000000/102700000/102691800/102691797/08169c3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Compostela 301 | Terrace/patio](https://images.trvl-media.com/lodging/103000000/102700000/102691800/102691797/7be4730a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Compostela 301](https://images.trvl-media.com/lodging/103000000/102700000/102691800/102691797/3ebd5cdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Compostela 302 | Living area](https://images.trvl-media.com/lodging/103000000/102700000/102691800/102691797/f8cacbf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Compostela Estadio

[](https://www.expedia.ca/Compostela-EStadio.h102691797.Hotel-Information)

Laureles - Estadio

CA $91

CA $120 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Compostela-EStadio.h102691797.Hotel-Information)

![Townhome | Living room](https://images.trvl-media.com/lodging/124000000/123610000/123600700/123600663/7bb858cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Dining room](https://images.trvl-media.com/lodging/124000000/123610000/123600700/123600663/c274428a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome](https://images.trvl-media.com/lodging/124000000/123610000/123600700/123600663/w5566h3712x0y0-4a109281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Townhome | Living room](https://images.trvl-media.com/lodging/124000000/123610000/123600700/123600663/8d5e29e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Bolivar by Wynwood House

[](https://www.expedia.ca/Medellin-Hotels-Casa-Bolivar-By-Wynwood-House.h123600663.Hotel-Information)

La América

CA $465

CA $465 total

Mar 1 - Mar 2

[](https://www.expedia.ca/Medellin-Hotels-Casa-Bolivar-By-Wynwood-House.h123600663.Hotel-Information)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/123000000/122760000/122759300/122759216/9d5a9556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/123000000/122760000/122759300/122759216/541f2861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/123000000/122760000/122759300/122759216/26398955.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Blackout drapes, free WiFi](https://images.trvl-media.com/lodging/123000000/122760000/122759300/122759216/e9634c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Otalu Suites

[](https://www.expedia.ca/Medellin-Hotels-Otalu-Suites.h122759216.Hotel-Information)

La América

CA $55

CA $70 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Medellin-Hotels-Otalu-Suites.h122759216.Hotel-Information)

![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/115000000/114380000/114372200/114372124/e8cfac0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathroom](https://images.trvl-media.com/lodging/115000000/114380000/114372200/114372124/dd1be205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/115000000/114380000/114372200/114372124/e735edc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi](https://images.trvl-media.com/lodging/115000000/114380000/114372200/114372124/bc94ba90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL FARO 78

[](https://www.expedia.ca/Medellin-Hotels-HOTEL-FARO-78.h114372124.Hotel-Information)

Medellin

2.0/10

(1 review)

"The host never contacted me once I got there. I had to booked another hotel."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis Joel

CA $106

CA $106 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Medellin-Hotels-HOTEL-FARO-78.h114372124.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/112000000/111280000/111279000/111278908/1f95ee51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, Pool View](https://images.trvl-media.com/lodging/112000000/111280000/111279000/111278908/9cc70bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Room, Pool View](https://images.trvl-media.com/lodging/112000000/111280000/111279000/111278908/e4dda976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/112000000/111280000/111279000/111278908/cee3c638.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Gracia Hotel & Spa

[](https://www.expedia.ca/San-Jeronimo-Hotels-La-Gracia-Hotel-Spa.h111278908.Hotel-Information)

San Jerónimo

8.8/10

Excellent

(5 reviews)

"Muy bonita la propiedad, limpio, buena comida No me gusto el ruido continuo de otras propiedades"

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Andres

CA $284

CA $284 total

Feb 19 - Feb 20

[](https://www.expedia.ca/San-Jeronimo-Hotels-La-Gracia-Hotel-Spa.h111278908.Hotel-Information)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216500/112216489/4a41fd1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216500/112216489/3bf8b843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216500/112216489/7f1ae845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216500/112216489/3fbc4629.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Jacuzzi Comfort Aparta-suite Stadio Rosa Negra

[](https://www.expedia.ca/Medellin-Hotels-Jacuzzi-Comfort-Aparta-Suite-Stadio-Rosa-Negra.h112216489.Hotel-Information)

Laureles - Estadio

9.0/10

Wonderful

(2 reviews)

"Very nice & friendly staff, nice & clean place, very good value for the price, I will be back here "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Emad

CA $117

CA $160 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Medellin-Hotels-Jacuzzi-Comfort-Aparta-Suite-Stadio-Rosa-Negra.h112216489.Hotel-Information)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116240000/116234000/116233929/26ed34c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, free WiFi, bed sheets](https://images.trvl-media.com/lodging/117000000/116240000/116234000/116233929/453e7250.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave](https://images.trvl-media.com/lodging/117000000/116240000/116234000/116233929/7d4a1d09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![LED TV](https://images.trvl-media.com/lodging/117000000/116240000/116234000/116233929/2b69865a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Monteclaro Campestre

[](https://www.expedia.ca/Sopetran-Hotels-Monteclaro-Campestre.h116233929.Hotel-Information)

Sopetran

CA $127

CA $183 total

Feb 12 - Feb 13

[](https://www.expedia.ca/Sopetran-Hotels-Monteclaro-Campestre.h116233929.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/91000000/90840000/90837900/90837848/dae6831a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/91000000/90840000/90837900/90837848/5da8bd21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/91000000/90840000/90837900/90837848/f9de67b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/91000000/90840000/90837900/90837848/fdde8a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Glamping Mirador de Santa Fe 

[](https://www.expedia.ca/Sopetran-Hotels-Glamping-Mirador-De-Santa-Fe.h90837848.Hotel-Information)

Sopetrán

2.0/10

(1 review)

CA $243

CA $243 total

Feb 16 - Feb 17

[](https://www.expedia.ca/Sopetran-Hotels-Glamping-Mirador-De-Santa-Fe.h90837848.Hotel-Information)

![Apartment](https://images.trvl-media.com/lodging/126000000/125440000/125433500/125433483/dea2238f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/126000000/125440000/125433500/125433483/887cd229.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/126000000/125440000/125433500/125433483/8b2e7327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/126000000/125440000/125433500/125433483/d866bd0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NOK Peaceful 3BR in Medellin

[](https://www.expedia.ca/Medellin-Hotels-NOK-Peaceful-3BR-In-Medellin.h125433483.Hotel-Information)

La América

CA $160

CA $234 total

Feb 15 - Feb 16

[](https://www.expedia.ca/Medellin-Hotels-NOK-Peaceful-3BR-In-Medellin.h125433483.Hotel-Information)

![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425897/6b117f82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425897/1d874ddc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425897/4ce12ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425897/18f2cbe0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stadio Aparta-suite Bliss Rosa Negra

[](https://www.expedia.ca/Medellin-Hotels-Stadio-Aparta-Suite-Bliss-Rosa-Negra.h116425897.Hotel-Information)

Laureles - Estadio

CA $137

CA $228 total

Feb 15 - Feb 16

[](https://www.expedia.ca/Medellin-Hotels-Stadio-Aparta-Suite-Bliss-Rosa-Negra.h116425897.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425833/2eb0631d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425833/d0d71a83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425833/47975eeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116425900/116425833/68d4dab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Charming Stadio Retreat Rosa Negra Aparta-suite

[](https://www.expedia.ca/Medellin-Hotels-Charming-Stadio-Retreat-Rosa-Negra-Aparta-Suite.h116425833.Hotel-Information)

Laureles - Estadio

CA $49

CA $83 total

Feb 17 - Feb 18

[](https://www.expedia.ca/Medellin-Hotels-Charming-Stadio-Retreat-Rosa-Negra-Aparta-Suite.h116425833.Hotel-Information)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116422300/116422247/27e8507d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116422300/116422247/99692864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116422300/116422247/52283a0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/117000000/116430000/116422300/116422247/150b0054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Stadio Suite Rosa Negra Retreat

[](https://www.expedia.ca/Medellin-Hotels-Cozy-Stadio-Suite-Rosa-Negra-Retreat.h116422247.Hotel-Information)

Laureles - Estadio

CA $95

CA $138 total

Feb 24 - Feb 25

[](https://www.expedia.ca/Medellin-Hotels-Cozy-Stadio-Suite-Rosa-Negra-Retreat.h116422247.Hotel-Information)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216600/112216503/627dc402.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216600/112216503/0614f50f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216600/112216503/a1f46ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (2 Bedrooms) | Floor plan](https://images.trvl-media.com/lodging/113000000/112220000/112216600/112216503/e7f81450.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfy Aparta-suite Stadio Rosa Negra

[](https://www.expedia.ca/Medellin-Hotels-Comfy-Aparta-Suite-Stadio-Rosa-Negra.h112216503.Hotel-Information)

Laureles - Estadio

CA $209

CA $252 total

Feb 16 - Feb 17

[](https://www.expedia.ca/Medellin-Hotels-Comfy-Aparta-Suite-Stadio-Rosa-Negra.h112216503.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-25&endDate=2026-02-26&regionId=6143343&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=CABIN)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APARTMENT)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VACATION_HOME)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VILLA)

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APART_HOTEL)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Fe+de+Antioquia%2C+Antioquia%2C+Colombia&regionId=6143343&latLong=6.55624%2C-75.827766&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=COTTAGE)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-De-Antioquia-Vacation-Rentals.d6143343.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Fe-De-Antioquia-Vacation-Rentals.d6143343.Travel-Guide-VacationRentals)

## Top Santa Fe de Antioquia Hotel Reviews

![Hotel Boutique Al Alma](https://images.trvl-media.com/lodging/97000000/96670000/96661800/96661794/185fd206_y.jpg)

### Hotel Boutique Al Alma

10/10 Excellent

"The stunning ambience, decor and customer service make it a unique and wonderful stay."

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Hotel-Boutique-Al-Alma.h96661794.Hotel-Information)

![Arde La Selva](https://images.trvl-media.com/lodging/109000000/108290000/108283700/108283692/38d256db_y.jpg)

### Arde La Selva

10/10 Excellent

"The room was clean, the property was absolutely gorgeous, the staff excells in customer service"

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Arde-La-Selva.h108283692.Hotel-Information)

![Finca Hotel Guadalupe](https://images.trvl-media.com/lodging/90000000/89580000/89575600/89575597/a8ade979_y.jpg)

### Finca Hotel Guadalupe

10/10 Excellent

"Una finca espectacular con Linda vegetacion, piscina de buen tamaño, staff con excellence servicio , super limpio "

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Guadalupe-Hotel-Boutique.h89575597.Hotel-Information)

![Selva Maria Hotel Boutique](https://images.trvl-media.com/lodging/103000000/102500000/102498900/102498829/d0f117ad_y.jpg)

### Selva Maria Hotel Boutique

10/10 Excellent

"Clean room!! Amazing staff! Great location! Only negative was a rooster woke me up early, but that was perfect because the cooked breakfast was wonderful. "

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Selva-Maria-Hotel-Boutique.h102498829.Hotel-Information)

![Hotel Mariscal Robledo](https://images.trvl-media.com/lodging/5000000/4300000/4294700/4294693/8c9c87e8_y.jpg)

### Hotel Mariscal Robledo

10/10 Excellent

"Excellent service. Very clean and very conscientious about respecting the convenience of all guests "

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Hotel-Mariscal-Robledo.h4294693.Hotel-Information)

![Curazao Hotel](https://images.trvl-media.com/lodging/92000000/91820000/91816900/91816803/78fff740_y.jpg)

### Curazao Hotel

10/10 Excellent

"Location. Staff attitude"

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Curazao-Hotel.h91816803.Hotel-Information)

![Casa Bixa Hotel Boutique by HMC - Mayores de 12 años](https://images.trvl-media.com/lodging/67000000/66130000/66120500/66120495/48f5a9d2_y.jpg)

### Casa Bixa Hotel Boutique by HMC - Mayores de 12 años

10/10 Excellent

"Very attentive staff. Very nice breakfast, with eggs if you would like them. Lorena was very helpful at check in and looked after are needs throughout our 3 day stay. Since the hotel is in Santa Fe but not right at central square, not noisy at night and close to highway to Medellín to get back to Medellin from Santa Fe."

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Casa-Bixa-Hotel-Boutique.h66120495.Hotel-Information)

![Hotel Porton del Sol ](https://images.trvl-media.com/lodging/94000000/93840000/93834200/93834159/fcaa15a0_y.jpg)

### Hotel Porton del Sol 

10/10 Excellent

"Clean and good facilities "

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Hotel-Porton-Del-Sol.h93834159.Hotel-Information)

![Hotel San Sebastian del Tonusco](https://images.trvl-media.com/lodging/90000000/89940000/89933300/89933227/4fdd9de9_y.jpg)

### Hotel San Sebastian del Tonusco

10/10 Excellent

"I was welcomed by three employees of the hotel with such warmth, I immediately felt at home. Laura, in particular, was so attentive to me during my entire stay. I was sad to leave. A wonderful experience. The only caveat is that it's a little far from the main town, but the hotel can arrange for a Tuk Tuk for you (very cheap and fun). "

[](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels-Hotel-San-Sebastian-Del-Tonusco.h89933227.Hotel-Information)

## Find out more about Santa Fe de Antioquia

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Fe de Antioquia. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

## Explore a world of travel with Expedia

- Trending destinations on Expedia.ca

### Trending destinations on Expedia.ca

- [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals)
- [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals)
- [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Tofino Vacation Rentals ](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals)
- [Calgary Vacation Rentals ](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals)
- [Costa Rica Vacation Rentals ](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations)
- [Vancouver Island Vacation Rentals ](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals)
- [Puerto Vallarta Vacation Rentals ](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals)
- [Hawaii Vacation Rentals ](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Toronto Vacation Rentals ](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals)
- [Banff Vacation Rentals ](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals)
- [Penticton Vacation Rentals ](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals)
- [Osoyoos Vacation Rentals ](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals)
- [Mont Tremblant Vacation Rentals ](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals)
- [Big White Ski Resort Vacation Rentals ](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals)
- [Ontario Vacation Rentals ](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations)
- [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
- [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

## Frequently asked questions

### Can I find a vacation rental in Santa Fe de Antioquia?

### What are some of the best vacation home rentals that Santa Fe de Antioquia has to offer?

### How many vacation rentals are there in Santa Fe de Antioquia?

### What can I see and do in Santa Fe de Antioquia?

### What are vacation rentals like in Santa Fe de Antioquia?

### Expedia's Latest Trends

Hotels

- [Best Hotels in Puerto Triunfo](https://expedia.ca/Puerto-Triunfo-Hotels.d6270785.Travel-Guide-Hotels)
- [Santa Marta All Inclusive Resorts and Hotels](https://expedia.ca/Santa-Marta-Hotels-All-Inclusive-Hotel.0-0-d3221-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
- [Best Hotels in Guatapé](https://expedia.ca/Guatape-Hotels.d6154953.Travel-Guide-Hotels)
- [Best Hotels in San Andrés](https://expedia.ca/San-Andres-Hotels.d6024028.Travel-Guide-Hotels)
- [Best Hotels in El Peñol](https://expedia.ca/El-Penol-Hotels.d6346467.Travel-Guide-Hotels)
- [Best Hotels in Venecia](https://expedia.ca/Venecia-Hotels.d553248635943694283.Travel-Guide-Hotels)
- [Best Hotels in Támesis](https://expedia.ca/Tamesis-Hotels.d553248635939992884.Travel-Guide-Hotels)
- [Best Hotels in Betania](https://expedia.ca/Betania-Hotels.d553248634906928364.Travel-Guide-Hotels)
- [Best Hotels in Andes](https://expedia.ca/Andes-Hotels.d3000430695.Travel-Guide-Hotels)
- [Best Hotels in San Roque](https://expedia.ca/San-Roque-Hotels.d553248635810200528.Travel-Guide-Hotels)
- [5 Star Hotels in Guatapé](https://expedia.ca/5Star-Guatape-Hotels.s50-0-d6154953.Travel-Guide-Filter-Hotels)
- [Best Hotels in Santa Marta](https://expedia.ca/Santa-Marta-Hotels.d3221.Travel-Guide-Hotels)
- [San Andrés All Inclusive Resorts and Hotels](https://expedia.ca/San-Andres-Hotels-All-Inclusive-Hotel.0-0-d6024028-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
- [Guatapé Green Hotels](https://expedia.ca/Guatape-Hotels-Green-Sustainable.0-0-d6154953-tGreenSustainable.Travel-Guide-Filter-Hotels)
- [Best Hotels in Jericó](https://expedia.ca/Jerico-Hotels.d6350706.Travel-Guide-Hotels)

Flights

- [Flights to ADZ](https://expedia.ca/Cheap-Flights-To-San-Andres.d6024028.Travel-Guide-Flights)

Cars

- [Car rentals in Honda](https://expedia.ca/Car-Rentals-In-Honda.d6204207.Car-Rental-Guide)
- [Car rentals in Turbo](https://expedia.ca/Car-Rentals-In-Turbo.d3526.Car-Rental-Guide)

Activities

- [Things to do in Retiro](https://expedia.ca/Things-To-Do-In-Retiro.d6270810.Travel-Guide-Activities)
- [Things to do in Puerto Triunfo](https://expedia.ca/Things-To-Do-In-Puerto-Triunfo.d6270785.Travel-Guide-Activities)
- [Things to do in El Peñol](https://expedia.ca/Things-To-Do-In-El-Penol.d6346467.Travel-Guide-Activities)

Packages

- [Flight and Hotel San Andrés](https://expedia.ca/San-Andres.d6024028.Destination-Travel-Guides)
- [Flight and Hotel Santa Marta](https://expedia.ca/Santa-Marta.d3221.Destination-Travel-Guides)
- [Flight and Hotel Barbosa](https://expedia.ca/Barbosa.d6346138.Destination-Travel-Guides)

Vacation Rentals

- [Yarumal Short Term Rentals](https://expedia.ca/Yarumal-Vacation-Rentals.d3000445080.Travel-Guide-VacationRentals)

General

- [Visit Jericó](https://expedia.ca/Jerico.dx6350706)
- [Visit San Andrés](https://expedia.ca/San-Andres.dx6024028)
- [Visit Necoclí](https://expedia.ca/Necocli.dx2528)
- [Visit Rionegro](https://expedia.ca/Rionegro.dx181446)
- [Visit Guatapé](https://expedia.ca/Guatape.dx6154953)

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app