Title: Cheap Flights to Santa Fe de Antioquia from CA $65 - Expedia.ca ![Beautiful colonial town](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Tahino2000 ![](https://images.trvl-media.com/place/6143343/29cd441c-37d2-4bc5-a439-b1f1c5081a7c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights to Santa Fe de Antioquia from CA $65 [View CA $65 flight on Mon, Feb 9, 2026](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:PEI,to:MDE,departure:09/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:64.20&airProductToken=AQowCi4IzIIBEgQ0MzQxGI9BIOwgKNTdhAMw_N2EAzhPQABYAWoCUVByCE8wMFFQR1pUEgoIARABGAEqAkxBGAEiBAgBEAEoAigEKAYwAQ) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only [Santa Fe de Antioquia Travel Guide](https://expedia.ca/Santa-Fe-De-Antioquia.dx6143343)[Hotels in Santa Fe de Antioquia](https://expedia.ca/Santa-Fe-De-Antioquia-Hotels.d6143343.Travel-Guide-Hotels)[Things to do in Santa Fe de Antioquia](https://expedia.ca/Things-To-Do-In-Santa-Fe-De-Antioquia.d6143343.Travel-Guide-Activities)[Santa Fe de Antioquia Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Fe-De-Antioquia.d6143343.Car-Rental-Guide)[Santa Fe de Antioquia Vacation Packages](https://expedia.ca/Santa-Fe-De-Antioquia.d6143343.Destination-Travel-Guides) ## Popular airlines to Santa Fe de Antioquia - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Spirit Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_NK.svg) Spirit Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"NK"}}]) - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![JetBlue Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_B6.svg) JetBlue Airways [](https://www.expedia.ca/Flights-Search?leg1=from:CMH,to:Santa Fe de Antioquia, Antioquia, Colombia,departure:08/01/2026TANYT&leg2=from:Santa Fe de Antioquia, Antioquia, Colombia,to:CMH,departure:15/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"B6"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - 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Prices were available within the past 7 days and start at CA $65 for one-way flights and CA $129 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Sat, Feb 28 - Tue, Mar 17 PEI Pereira MDE Medellin CA $129 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PEI,to:MDE,departure:28/02/2026TANYT&leg2=from:MDE,to:PEI,departure:17/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:128.80&airProductToken=AQoiCiAIzIIBEgQ0MzQxGI9BIOwgKLSzhgMw3LOGAzhPQABYAQoiCiAIzIIBEgQ0MzQyGOwgII9BKP_xhwMwsfKHAzhPQABYARIKCAEQARgBKgJMQRgBIgQIARABKAQwAQ) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Sat, Feb 28 - Wed, Mar 18 PEI Pereira MDE Medellin CA $135 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PEI,to:MDE,departure:28/02/2026TANYT&leg2=from:MDE,to:PEI,departure:18/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:134.80&airProductToken=AQoiCiAIzIIBEgQ0MzQxGI9BIOwgKLSzhgMw3LOGAzhPQABYAQoiCiAIzIIBEgQ0MzQyGOwgII9BKJ_9hwMw0f2HAzhRQABYARIKCAEQARgBKgJMQRgBIgQIARABKAQwAQ) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Fri, Mar 6 - Sat, Mar 7 PEI Pereira MDE Medellin CA $137 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PEI,to:MDE,departure:06/03/2026TANYT&leg2=from:MDE,to:PEI,departure:07/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:136.60&airProductToken=AQpECiAIzIIBEgQ0MjIxGI9BIMEzKIbzhgMwwfOGAzhPQABYAQogCMyCARIENDAxMBjBMyDsICjt-oYDMKn7hgM4T0ABWAEKIgogCMyCARIENDM0MhjsICCPQSi_gYcDMPGBhwM4T0AAWAESCggBEAEYASoCTEEYASIECAEQASgEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sat, Jan 31 - Fri, Feb 6 PEI Pereira MDE Medellin CA $234 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PEI,to:MDE,departure:31/01/2026TANYT&leg2=from:MDE,to:PEI,departure:06/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:233.40&airProductToken=AQo1CjMIwawBEgQ5NjE4GI9BIOwgKJX6gwMwzPqDAzhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJJUksKNQozCMGsARIEOTYxNxjsICCPQSj7vIQDMK29hAM4U0AAWAFqB0NMQVNTSUNyCFNFT0IySVJLEgoIARABGAEqAkxSGAEiBAgBEAEoAigDKAQwAQ) ![APG Distribution System](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/GP.gif) Sat, Jan 31 - Fri, Feb 6 PEI Pereira EOH Medellin CA $271 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PEI,to:EOH,departure:31/01/2026TANYT&leg2=from:EOH,to:PEI,departure:06/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:270.60&airProductToken=AQo0CjIIwWISBDU1NDIYj0EgxDsoqviDAzDX-IMDOE1AAFgBcgVNT1dWRXoKCNaKARIENTU0Mgo0CjIIwWISBDU1MzkYxDsgj0EoorqEAzDPuoQDOE1AAFgBcgVNT1dWRXoKCNaKARIENTUzORIKCAEQARgBKgJHUBgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Columbus (CMH) to Medellín (MDE) ### September is typically the cheapest month to fly From CA $360 - CA $915 per traveller. ## Frequently asked questions ### What is the name of Santa Fe de Antioquia's airport? ### What airport is best to fly into Santa Fe de Antioquia? ### How many airlines fly to Santa Fe de Antioquia? ### Which airlines fly to Santa Fe de Antioquia? ### How many nonstop flights are there to Santa Fe de Antioquia? ### Where are the most popular flights to Santa Fe de Antioquia departing from? ### How long is the flight to Santa Fe de Antioquia Airport? ### How to book the cheapest flight to Santa Fe de Antioquia? ### Do you have any tips for my flight to Santa Fe de Antioquia? > - Firstly, and most importantly, pack in your passport, important documents, cash and vital medications. Next, you'll want some entertainment to help pass the time. A juicy novel and a tablet crammed with your favourite shows are some terrific options. If you hope to take a quick snooze, a quality neck pillow and a pair of earplugs will also be useful. Finally, leave space for a toothbrush and some facial wipes so you'll hop off the plane looking fresh and raring to go. > > > Do not pack the following items in your hand luggage: > > > - While the list of prohibited items can differ between air carriers, the general guide to follow is avoid carrying anything sharp, flammable or explosive. This includes screwdrivers, knives, aerosol cans and bleaching agents. Sports equipment like baseball bats, and objects that could injure passengers, such as swords and guns, won't be allowed on board either. > > > What to wear on a flight: > > > - Your goal here is to feel as comfortable as possible. Go for shoes that are easy to pull on and off, dress in loose, natural-fibre clothing and don't forget to take a pullover in case you get cold in the cabin. > - Deep vein thrombosis (DVT), a blood clotting condition caused by extended periods of inactivity, can be a risk on long-haul flights. Try to walk around the cabin and stretch your legs or do some gentle exercises in your seat to improve your circulation. ### How to get through airport security fast when flying to Santa Fe de Antioquia? > - First things first. Your boarding pass and passport will need to be shown to security personnel. Have them close by so you don't hold up the queue. > - Next up, both you and your carry-on bag will be X-rayed. To make the process quick and painless, take off anything that is likely to trigger the alarm. Items like your belt, jacket and earphones need to go through the machine. > - All your electronics, including your phone and tablet, are also required to be scanned. > - Travelling with your favourite perfume or cologne? Not a problem. As long as the volume is no larger than 3.4 ounces (100 millilitres) and it's stored in a zip-lock bag, you can keep it with you in your carry-on luggage. > - Choosing your footwear wisely can save you several precious minutes. Boots and bulky shoes are often required to be removed and X-rayed separately. Slip-on sneakers usually aren't. > - Sharp items like knives are prohibited in the cabin. They'll be confiscated at security, so pack them safely away in your checked suitcase. ## Book with confidence Expedia.ca gives you the best tools to secure great deals on flights to Santa Fe de Antioquia. Use our easy and convenient booking engine to browse nonstop flights and convenient departure points every day of the year. Search airfares from the top airlines to book your perfect flight to Santa Fe de Antioquia. Whatever your travel needs, you can always rely on Expedia.ca to help you find cheap flights to Santa Fe de Antioquia. Using our booking engine is simple - just type in your points of travel and preferred dates and Expedia.ca does the rest! If your travel times are flexible, you can find even better bargains by adjusting your flight dates. Browse connecting flights to increase your chances of finding even lower fares. Thanks to Expedia's Best Price Guarantee, you can book your Santa Fe de Antioquia flights with full confidence knowing that you've found the best deal online. Expedia.ca makes the booking process easy and stress-free by offering support along the entire way. Our friendly staff is available 24 hours a day to provide assistance and help you book your ticket. Call us toll-free at 1-888-397-3342 to answer any questions that you may have about your trip to Santa Fe de Antioquia. Looking to save even more? Get additional savings by bundling your Santa Fe de Antioquia flight with a hotel and/or car rental to create a bargain travel package. Early birds can discover terrific savings by booking in advance while last minute travelers can enjoy great last minute deals. With Expedia.ca, there's no shortage of options to save even more on your Santa Fe de Antioquia trip! ## Travel information | Destination airport | José María Córdova Intl. | | ----------------------------- | ------------------------ | | Destination airport IATA code | MDE | | Destination city name | Medellín | | Roundtrip price | CA $146 | ## Trending flights to Santa Fe de Antioquia Prices were available within the past 7 days and start at CA $65 for one-way flights and CA $129 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Arajet](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DM.gif) Fri, Feb 27 - Tue, Mar 10 YYZ Toronto MDE Medellin CA $359 Roundtrip found 2 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:YYZ,to:MDE,departure:27/02/2026TANYT&leg2=from:MDE,to:YYZ,departure:10/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:358.24&airProductToken=AQppCjMIxJoBEgQ1ODA1GJjOASCPTSiyo4YDMNmlhgM4waABQABYAWoFQkFTSUNyB0FQQkFTT1cKMgjEmgESBDE3MzIYj00g7CAo6KaGAzCKqIYDOMGgAUAAWAFqBUJBU0lDcgdBUEJBU09XCmkKMgjEmgESBDE3MzMY7CAgj00otqKHAzDgo4cDOMGgAUAAWAFqBUJBU0lDcgdBUEJBU09XCjMIxJoBEgQ1ODYyGI9NIJjOASjJpIcDMOumhwM4waABQABYAWoFQkFTSUNyB0FQQkFTT1cSCggLEAEYCCoCRE0YASIECAEQASgCMAM) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [2 Star Hotels in Medellin ](https://www.expedia.ca/2Star-Medellin-Hotels.s20-0-d2246.Travel-Guide-Filter-Hotels) - 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