Santa Clara Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Your Santa Clara Vacation

Art, food, entertainment and more … There's so much to experience with a Santa Clara vacation package. And with the ability to customize your city getaway, it's guaranteed to be one you won't forget. Eager to sightsee but not sure where to start? Any trip to Santa Clara should include Culebra Cut. Your dream Santa Clara vacation is a couple of clicks away. Search flights, accommodations and more on Expedia for a getaway that's tailored just for you.

Top Santa Clara Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Decapolis Hotel Panama City

Decapolis Hotel Panama City

San Francisco
CA $1,164
per person
Nov 18 - Nov 25
found 11 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,708 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
CA $1,615
per person
Nov 15 - Nov 22
found 11 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Loved my stay! The staff was extremely helpful and the amenities were great!

Reviewed on Sep 13, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
CA $1,265
per person
Nov 15 - Nov 22
found 11 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.4/10 Very good! (1,693 reviews)
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Tocumen Airport
CA $1,210
per person
Nov 18 - Nov 25
found 11 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
8.6/10 Excellent! (1,811 reviews)
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

San Francisco
CA $1,346
per person
Nov 18 - Nov 25
found 11 hours ago
Roundtrip flight included
Montreal (YMQ) to Panama City (PTY)
9/10 Wonderful! (1,098 reviews)

Ready to book your vacation to Santa Clara?

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Santa Clara Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
CA $191
CA $210 total
Sep 27 - Sep 28
includes taxes & fees
Hotel Riu Plaza Panama
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
Fully refundableReserve now, pay when you stay
CA $254
CA $280 total
Oct 12 - Oct 13
includes taxes & fees
9/10 Wonderful! (1,015 reviews)
"Loved my stay! The staff was extremely helpful and the amenities were great!"

Reviewed on Sep 13, 2026

Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
CA $200
CA $200 total
Sep 21 - Sep 22
includes taxes & fees
Megapolis Hotel Panamá
See all 1,768 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Clara attractions

Culebra Cut

8.0/10 (14 reviews)
You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.
See properties

What to do in Santa Clara

Half day of Panama city and canal tour: shared and private

Half day of Panama city and canal tour: shared and private

CA $92
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
Monkey and Sloth Jungle Habitat Panama Tour

Monkey and Sloth Jungle Habitat Panama Tour

CA $58
per adult
96% of travellers recommend
Monkey and Sloth Jungle Habitat Panama Tour
Magnificent Gatun lake

Monkey Watch and Gatun Lake Wildlife Safari Private Tour

CA $104
per adult
Monkey Watch and Gatun Lake Wildlife Safari Private Tour
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara vacation package cost?
You can pick up a vacation package to this destination from CA $1,164 on Expedia. However, how much your vacation to Santa Clara costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Clara?
September, October and November are great times to search for cheap Santa Clara vacation packages. Opting to travel in less busy months means you can usually find reduced prices on flights and hotels.
How many days is enough for Santa Clara?
With a well-organized travel plan, you can easily tick off the top Santa Clara sights in a handful of days. But if you prefer to discover hidden gems or go on day trips, think about booking your Santa Clara vacation for longer.
How to find the best Santa Clara package deals?
Use Expedia's filters to find some terrific Santa Clara package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or search for Santa Clara package deals in the low season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santa Clara vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can customize your Santa Clara getaway to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa Clara?
If you're planning a spontaneous Santa Clara adventure, check out our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can score terrific deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Clara?
  1. Choose your dates: What you'd like to do in Santa Clara and your preferred season can help you decide when to get away.
  2. Plan your budget wisely: On top of the price of your stay, you should factor in other expenses. These include flights, food and transportation. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to Santa Clara.
  3. Decide how long to go away for: Now that you know more about Santa Clara, you can work out the right length of your break. Create a rough itinerary and allocate enough time to cover everything you want to see.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Clara vacation package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.