Title: Santa Clara Vacation Rentals from CA $132: Short-Term Rentals for 2026 | Expedia.ca

[Hotels in Santa Clara](https://expedia.ca/Santa-Clara-Hotels.d553248623287315690.Travel-Guide-Hotels)[Things to do in Santa Clara](https://expedia.ca/Things-To-Do-In-Santa-Clara.d553248623287315690.Travel-Guide-Activities)[Santa Clara Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Clara.d553248623287315690.Car-Rental-Guide)[Santa Clara Vacation Packages](https://expedia.ca/Santa-Clara.d553248623287315690.Destination-Travel-Guides)

![Adobe](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/553248623287315690/4fe3b50e-a6f6-406a-8784-202fa5ed50eb.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Check prices for these dates

In two weeks

[Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248623287315690&startDate=2026-03-06&endDate=2026-03-08&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=553248623287315690&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 15 - May 17](https://www.expedia.ca/Hotel-Search?regionId=553248623287315690&startDate=2026-05-15&endDate=2026-05-17&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 12 - Jun 14](https://www.expedia.ca/Hotel-Search?regionId=553248623287315690&startDate=2026-06-12&endDate=2026-06-14&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Clara vacation rentals

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f23a333a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Arcadia Condo Suites

[](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

Costa del Este

9.4/10

Exceptional

(218 reviews)

"Really loved this place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alejandra

CA $113

CA $188 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/2e90f0b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/69e10c95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/71a0d50b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/68000000/67320000/67311700/67311633/ec2b8abb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartamento a 10 minutos del aeropuerto

[](https://www.expedia.ca/Panama-City-Hotels-Casa-De-Flores.h67311633.Hotel-Information)

Panamá

CA $55

CA $112 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Panama-City-Hotels-Casa-De-Flores.h67311633.Hotel-Information)

![Private beach](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/30ff294e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/e0ea3259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Room, Courtyard View](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/070ae157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/e0ba1e08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

[](https://www.expedia.ca/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information)

Vacamonte

10/10

Exceptional

(2 reviews)

"Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cynthia

CA $33

CA $51 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information)

![Apartment](https://images.trvl-media.com/lodging/124000000/123170000/123162800/123162773/7825c8c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123170000/123162800/123162773/afec0f45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123170000/123162800/123162773/b1d6d6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123170000/123162800/123162773/aa365767.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Dovle 510 in Ciudad de Panam

[](https://www.expedia.ca/Panama-City-Hotels-Dovle-510-In-Ciudad-De-Panam.h123162773.Hotel-Information)

San Francisco

CA $174

CA $191 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/Panama-City-Hotels-Dovle-510-In-Ciudad-De-Panam.h123162773.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/97000000/96030000/96026500/96026407/67c30365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, offices](https://images.trvl-media.com/lodging/97000000/96030000/96026500/96026407/ff55656d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/97000000/96030000/96026500/96026407/55bbf1ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/97000000/96030000/96026500/96026407/53890584.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### w\* | Prestigious 1BR in San Francisco

[](https://www.expedia.ca/Panama-City-Hotels-W-Prestigious-1BR-In-San-Francisco.h96026407.Hotel-Information)

San Francisco

10/10

Exceptional

(1 review)

"Everything was as described. Restaurants were conveniently located. View was an added bonus and was better than pictured. We were able to enjoy the gym. The pool was a little cool but still enjoyable. Would recommend this host."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ruben O.

CA $129

CA $190 total

includes taxes & fees

Feb 25 - Feb 26

[](https://www.expedia.ca/Panama-City-Hotels-W-Prestigious-1BR-In-San-Francisco.h96026407.Hotel-Information)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/375f6530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/2f0279c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Centriqo by Wynwood house 

[](https://www.expedia.ca/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information)

Veracruz

CA $149

CA $209 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/979e7b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/aef1fc6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, free WiFi, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/163d5c43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/114000000/113740000/113732000/113731940/c727a57f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### LILIA HOUSE 10 MINUTES AIRPORT

[](https://www.expedia.ca/Las-Mananitas-Hotels-LILIA-HOUSE-10-MINUTES-AIRPORT.h113731940.Hotel-Information)

Panamá

CA $62

CA $108 total

includes taxes & fees

Feb 25 - Feb 26

[](https://www.expedia.ca/Las-Mananitas-Hotels-LILIA-HOUSE-10-MINUTES-AIRPORT.h113731940.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (10C) | Living area](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms (17B) | Living area](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/f99400a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Apartments Atlapa

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information)

San Francisco

8.0/10

Very good

(30 reviews)

"The place was clean nice an its comfortable an the view is to kill for amazing ‼️"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Odaine

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/120000000/119070000/119065100/119065098/c5e2c44a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/120000000/119070000/119065100/119065098/330a6f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, internet, bed sheets](https://images.trvl-media.com/lodging/120000000/119070000/119065100/119065098/c2fb1613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/120000000/119070000/119065100/119065098/d616d4fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Excellent beach apartment with excellent amenities

[](https://www.expedia.ca/Veracruz-Hotels-Excellent-Beach-Apartment-With-Excellent-Amenities.h119065098.Hotel-Information)

Provincia de Panamá Oeste

CA $111

CA $186 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Veracruz-Hotels-Excellent-Beach-Apartment-With-Excellent-Amenities.h119065098.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/93000000/92990000/92983200/92983185/7f976ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/93000000/92990000/92983200/92983185/0eb377cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92990000/92983200/92983185/c6357c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92990000/92983200/92983185/319e6a8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Oasis with pool near panama canal

[](https://www.expedia.ca/Panama-City-Hotels-Oasis-With-Pool-Near-Panama-Canal.h92983185.Hotel-Information)

Panamá

9.4/10

Exceptional

(30 reviews)

"The place was really comfortable and very close to the city and other tourist attractions and even close to the airport. My family really enjoyed the the pool area and the convenience of the spacious house! Would recommend and I would rent this place on my next vacation."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wendy F.

CA $260

CA $376 total

includes taxes & fees

Feb 26 - Feb 27

[](https://www.expedia.ca/Panama-City-Hotels-Oasis-With-Pool-Near-Panama-Canal.h92983185.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 2 Double Beds, Non Smoking, Connecting Rooms](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/da2b9bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio, 1 King Bed, Non Smoking, Connecting Rooms](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/d9012efa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Las Clementinas

[](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information)

Casco Viejo

9.4/10

Exceptional

(181 reviews)

"Fabulous room and wonderful people that work there. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Leah

CA $226

CA $249 total

includes taxes & fees

Mar 23 - Mar 24

[](https://www.expedia.ca/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information)

![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment | Living area](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casco View Apartments

[](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information)

Santa Ana

9.0/10

Wonderful

(72 reviews)

"We live this property and stay here whenever we are in town."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

chris

[](https://www.expedia.ca/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information)

![Comfort Suite, 1 Queen Bed with Sofa bed](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/53efba5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Suite](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Palma Aparta Suite

[](https://www.expedia.ca/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information)

Amador

8.4/10

Very good

(7 reviews)

"All ways clean and ready to used ,no buddy "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Alberto

CA $105

CA $132 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/3d522a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/a729fcb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/0f2f6085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/7c14eac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 2BR w Terrace Lounge

[](https://www.expedia.ca/Panama-City-Hotels-Spacious-2BR-W-Terrace-Lounge.h123391239.Hotel-Information)

San Francisco

CA $222

CA $332 total

includes taxes & fees

Mar 11 - Mar 12

[](https://www.expedia.ca/Panama-City-Hotels-Spacious-2BR-W-Terrace-Lounge.h123391239.Hotel-Information)

![An infinity pool](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/172b71e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/cffde6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/0c821668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/e0893bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beutiful Apartment, High Speed Internet, Excellent Location

[](https://www.expedia.ca/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information)

San Francisco

8.8/10

Excellent

(14 reviews)

"It could use a few lamps especially in the bedroom, some pictures on the walls. The curtains in the smaller bedroom didn’t close on the right side. It’s a bit run down for the price. The location is ok. It is in a neighborhood so must take a taxi. That was ok as taxis are everywhere. The view of the water is great as it has almost wrap around windows in the living/ social area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Teri

CA $128

CA $196 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information)

![Apartment, 3 Bedrooms | Living area](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/9e5233d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 2 Bedrooms](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/9e64cab9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 3 Bedrooms | Street view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/cc8558b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Boutique Apartments Panamá Coco del Mar

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information)

San Francisco

7.4/10

Good

(170 reviews)

"Clean room good place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gideon

CA $100

CA $302 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/7c635746.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury Apartment Piso 35 with City View

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information)

Bella Vista

CA $98

CA $107 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/7fec4ade.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment | Living area](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/2f5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/c6184862.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110790000/110785700/110785630/83a9c463.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yoo Panamá by Boutique Apartments

[](https://www.expedia.ca/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information)

Bella Vista

8.2/10

Very good

(62 reviews)

"Great location, wonderful views, spacious apartment, with comfortable bed and good ac. Amenities in the building are great too."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

alan

CA $102

CA $303 total

includes taxes & fees

Mar 2 - Mar 3

[](https://www.expedia.ca/Panama-City-Hotels-Yoo-Panama-By-Boutique-Apartments.h110785630.Hotel-Information)

![Interior detail](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/2453d7ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Double Room | View from room](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/c6d0b885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Double Queen Suite](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/db18ada2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Suite, Annex Building (King) | Living area](https://images.trvl-media.com/lodging/16000000/15980000/15979000/15978996/6f5654fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Isabela Suites

[](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information)

Casco Viejo

10/10

Exceptional

(178 reviews)

"Excellent place to stay in the Casco Viejo "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Zoe M

[](https://www.expedia.ca/Panama-City-Hotels-La-Isabela-Suites.h15978996.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/278cb749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/e4d966c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/4c5e63f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106270000/106266000/106265914/71ba504e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Luxury 1 bedroom apt free parking and Pool

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-1-Bedroom-Apt-Free-Parking-And-Pool.h106265914.Hotel-Information)

San Francisco

10/10

Exceptional

(1 review)

"El apto está muy bueno con vistas espectaculares. La limpieza impecable y la atención muy buena. El sitio dónde está ubicado es de los mejores de la ciudad."

![Spain](https://a.travel-assets.com/egds/marks/flags/es.svg)

Ricardo Alejandro

CA $104

CA $249 total

includes taxes & fees

Mar 25 - Mar 26

[](https://www.expedia.ca/Panama-City-Hotels-Luxury-1-Bedroom-Apt-Free-Parking-And-Pool.h106265914.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-08&endDate=2026-03-09&regionId=553248623287315690&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale 

Members save up to 40% on hotels and homes. Plan this year’s big trip and save. 

[Book now](https://expedia.ca/deals?rfrr=VR_SPRING_PROMO_553248623287315690)

## Find vacation rentals that suit your style

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=APARTMENT)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=CABIN)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=VILLA)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=CONDO)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=COTTAGE)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=VACATION_HOME)

Houseboats

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Clara%2C+Panam%C3%A1+Oeste+Province%2C+Panama&regionId=553248623287315690&latLong=9.030373%2C-79.748077&adults=2&startDate=2026-05-23&d1=2026-05-23&endDate=2026-05-26&d2=2026-05-26&lodging=HOUSE_BOAT)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Vacation-Rentals.d553248623287315690.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Clara-Vacation-Rentals.d553248623287315690.Travel-Guide-VacationRentals)

## Top Santa Clara Hotel Reviews

![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg)

### Decapolis Hotel Panama City

10/10 Excellent

"Great stay clean room good staff"

[](https://expedia.ca/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information)

![JW Marriott Panama](https://images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg)

### JW Marriott Panama

10/10 Excellent

"Great stay"

[](https://expedia.ca/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information)

![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg)

### Marriott Panama Hotel

10/10 Excellent

"No issues everything was very clean "

[](https://expedia.ca/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information)

![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg)

### Waymore Hotel Spa & Casino

10/10 Excellent

"Room was spotless and staff friendly and very courteous "

[](https://expedia.ca/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information)

![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg)

### Sheraton Grand Panama

10/10 Excellent

"That was good"

[](https://expedia.ca/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)

![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg)

### W Panama

10/10 Excellent

"They were great "

[](https://expedia.ca/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information)

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg)

### Hotel Riu Plaza Panama

10/10 Excellent

"Good"

[](https://expedia.ca/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information)

![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg)

### The Executive Hotel

10/10 Excellent

"Room was clean and well appointed. We arrived early and the reception staff were great getting our luggage stored for the day. Very friendly team here and service was excellent. Included breakfast was awesome and it was great value for money. "

[](https://expedia.ca/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information)

![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg)

### Plaza Paitilla Inn Hotel

10/10 Excellent

"Room and location are excellent. Everything was clean and nice. Staff were friendly. No issues at all. Thank you "

[](https://expedia.ca/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information)

## Find out more about Santa Clara

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Clara. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

## Explore a world of travel with Expedia

- Trending destinations on Expedia.ca

### Trending destinations on Expedia.ca

- [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals)
- [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals)
- [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Tofino Vacation Rentals ](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals)
- [Calgary Vacation Rentals ](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals)
- [Costa Rica Vacation Rentals ](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations)
- [Vancouver Island Vacation Rentals ](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals)
- [Puerto Vallarta Vacation Rentals ](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals)
- [Hawaii Vacation Rentals ](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Toronto Vacation Rentals ](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals)
- [Banff Vacation Rentals ](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals)
- [Penticton Vacation Rentals ](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals)
- [Osoyoos Vacation Rentals ](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals)
- [Mont Tremblant Vacation Rentals ](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals)
- [Big White Ski Resort Vacation Rentals ](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals)
- [Ontario Vacation Rentals ](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations)
- [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations)
- [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations)
- [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals)

## Frequently asked questions

### Can I find vacation rentals in Santa Clara?

### What are some of the best vacation home rentals that Santa Clara has to offer?

### What can I see and do in Santa Clara?

### What are vacation rentals like in Santa Clara?

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app