Santa Clara Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Clara Vacation

Art, food, entertainment and more … There's so much to experience with a Santa Clara vacation package. And with the ability to customize your city getaway, it's guaranteed to be one you won't forget. Eager to sightsee but not sure where to start? Any trip to Santa Clara should include Culebra Cut. Your dream Santa Clara vacation is a couple of clicks away. Search flights, accommodations and more on Expedia for a getaway that's tailored just for you.

Top Santa Clara Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Sep 14 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on Jul. 11, 2025

The Sands by Wynwood House

The Sands by Wynwood House

2 out of 5
Calidonia
Save 100% on your flight
per person
Sep 23 - Sep 30
found 5 hours ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
No reviews
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Sep 23 - Sep 30
found 5 hours ago
Roundtrip flight included
Montreal (YUL) to Panama City (PTY)
No reviews
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Sep 14 - Sep 21
found 3 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
No reviews
Hotel Plaza Herrera

Hotel Plaza Herrera

3 out of 5
Casco Viejo
Save 100% on your flight
per person
Sep 14 - Sep 21
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
10/10 Exceptional! (3 reviews)

Ready to book your vacation to Santa Clara?

 

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Santa Clara Hotel Deals

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is CA $157 per night from Jul 29 to Jul 30
CA $157
CA $173 total
Jul 29 - Jul 30
includes taxes & fees
9/10 Wonderful! (4,085 reviews)
"THE CENTER OF CITY, CLOSE TO NUMBER OF ACTIVITIES. WEEKDAY VERY CONGESTED ROADS."

Reviewed on Jul. 10, 2025

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is CA $335 per night from Aug 1 to Aug 2
CA $335
CA $335 total
Aug 1 - Aug 2
includes taxes & fees
7.2/10 Good! (1,002 reviews)

Reviewed on Jul. 10, 2025

Dreams Playa Bonita Panama - All Inclusive
Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is CA $171 per night from Jul 25 to Jul 26
CA $171
CA $188 total
Jul 25 - Jul 26
includes taxes & fees
8.4/10 Very Good! (891 reviews)
"a clean and nice hotel , Lobby area was very nice with some nice shopping places, the rooms need a little update especially the bathroom, the service was excellent friendly and courteous"

Reviewed on Jul. 8, 2025

Sheraton Grand Panama
See all 1,452 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

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Family Vacations

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Discover the most popular places to visit in Santa Clara

Culebra Cut

You can find out about the history of Santa Clara with a visit to Culebra Cut. Check out the casinos and top-notch restaurants in this walkable area.

Culebra Cut

What to do in Santa Clara

Panama City Tour and Panama Canal – Miraflores Locks Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

CA $48
per adult
100% of travellers recommend
Panama City Tour and Panama Canal – Miraflores Locks Experience
Gatun Lake boat ride

Panama Canal Monkey & Wildlife Boat Safari

CA $75
per adult
100% of travellers recommend
Panama Canal Monkey & Wildlife Boat Safari
Guided Jungle Adventure with Gatun Lake Cruise

Guided Jungle Adventure with Gatun Lake Cruise

CA $121
per adult
88% of travellers recommend
Guided Jungle Adventure with Gatun Lake Cruise
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara vacation package cost?
You can pick up a vacation package to this destination from CA $1,340 on Expedia. However, how much your vacation to Santa Clara costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Clara?
September, October and November are great times to search for cheap Santa Clara vacation packages. Opting to travel in less busy months means you can usually find reduced prices on flights and hotels.
How many days is enough for Santa Clara?
With a well-organized travel plan, you can easily tick off the top Santa Clara sights in a handful of days. But if you prefer to discover hidden gems or go on day trips, think about booking your Santa Clara vacation for longer.
How to find the best Santa Clara package deals?
Use Expedia's filters to find some terrific Santa Clara package deals. When you begin your search, simply set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or search for Santa Clara package deals in the low season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
Is it cheaper to book a Santa Clara vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and hotels separately. Better still, you can customize your Santa Clara getaway to match your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa Clara?
If you're planning a spontaneous Santa Clara adventure, check out our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can score terrific deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Clara?

  1. Choose your dates: What you'd like to do in Santa Clara and your preferred season can help you decide when to get away.
  2. Plan your budget wisely: On top of the price of your stay, you should factor in other expenses. These include flights, food and transportation. Also, put aside some extra funds for unexpected expenses that may crop up during your trip to Santa Clara.
  3. Decide how long to go away for: Now that you know more about Santa Clara, you can work out the right length of your break. Create a rough itinerary and allocate enough time to cover everything you want to see.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to find a Santa Clara vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.