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Santa Clara Vacation Rentals

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Our top choices for Santa Clara vacation rentals

1. Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.
3.0 star property
Vacamonte
8.4 out of 10, Very good, (5 reviews)
"Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach."
United States
Cynthia
The price is CA $28
CA $43 total
includes taxes & fees
Oct 11 - Oct 12
Habitación con entrada Privada en Playa Dorada + Kitchenette y baño.

2. Refugio Frente al Mar Vista Venao

Refugio Frente al Mar Vista Venao
3.0 star property
Veracruz
7.4 out of 10, Good, (3 reviews)
"The staff was very welcoming, the room was very clean and had all the commodities needed for a great experience! I highly recommend it and I'll definitely pay a second visit!"
United States
Victor
The price is CA $83
CA $91 total
includes taxes & fees
Oct 8 - Oct 9
Refugio Frente al Mar Vista Venao

3. La Palma Experience

La Palma Experience
3.0 star property
Amador
8.8 out of 10, Excellent, (13 reviews)
"I would recommend this hotel. It has a great location and offers a very pleasant experience."
United States
Juan Luis Perez
The price is CA $100
CA $111 total
includes taxes & fees
Oct 18 - Oct 19
La Palma Experience

4. Former Barracks of the U.S. Army

Former Barracks of the U.S. Army
Panamá
9.8 out of 10, Exceptional, (7 reviews)
"Jeff was very responsive and welcoming. The property is exactly as described."
United States
Kermit S.
The price is CA $90
CA $134 total
includes taxes & fees
Oct 8 - Oct 9
Former Barracks of the U.S. Army

5. w* | Classy 1BR in San Francisco w/ Pool

w* | Classy 1BR in San Francisco w/ Pool
San Francisco
10.0 out of 10, Exceptional, (3 reviews)
"It’s the best and it’s easy to use"
United States
Sari
The price is CA $119
CA $193 total
includes taxes & fees
Oct 12 - Oct 13
w* | Classy 1BR in San Francisco w/ Pool

6. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.6 out of 10, Excellent, (38 reviews)
"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."
United States
David
The price is CA $195
CA $219 total
includes taxes & fees
Oct 13 - Oct 14
Dovle Residences by HMS-Preferred Member

7. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (234 reviews)
"very nice place to stay"
United States
purabi
The price is CA $74
CA $281 total
includes taxes & fees
Oct 12 - Oct 13
Boutique Apartments Panamá Coco del Mar

8. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (49 reviews)
"Staff was great. Room has spectacular views. Air conditioning was great, super quiet in the bedroom. Rooftop pool and patio was delightful. Loved our stay!"
Canada
Gary
The price is CA $54
CA $216 total
includes taxes & fees
Oct 11 - Oct 12
Boutique Apartments Atlapa

9. Corporate Stays Arcadia | Executive Furnished Apartments

Corporate Stays Arcadia | Executive Furnished Apartments
4.0 star property
Costa del Este
9.2 out of 10, Wonderful, (390 reviews)
"Nice place good location"
United States
Rame
The price is CA $136
CA $160 total
includes taxes & fees
Nov 6 - Nov 7
Corporate Stays Arcadia | Executive Furnished Apartments

10. Cozy La Chorrera Villa With Private Patio & Nature Views

Cozy La Chorrera Villa With Private Patio & Nature Views
2.0 star property
La Chorrera
The price is CA $70
CA $77 total
includes taxes & fees
Oct 13 - Oct 14
Cozy La Chorrera Villa With Private Patio & Nature Views

11. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is CA $64
CA $288 total
includes taxes & fees
Nov 2 - Nov 3
Living 73 Panamá by Boutique Apartments

12. La Isabela Suites

La Isabela Suites
3.5 star property
Casco Viejo
10.0 out of 10, Exceptional, (212 reviews)
"Location in old town, across from Plaza Simon Bolivar, is the perfect place to venture around old town and the new city. Great restaurants and shops within easy walking distance. I relied on recommendations from the staff for a couple of things and their selections exceeded my expectations. Highly recommend staying if visiting Panama City."
United States
David
The price is CA $200
CA $222 total
includes taxes & fees
Nov 4 - Nov 5
La Isabela Suites

13. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is CA $67
CA $259 total
includes taxes & fees
Oct 20 - Oct 21
The Hub by Boutique Apartments

14. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (65 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is CA $161
CA $213 total
includes taxes & fees
Oct 18 - Oct 19
San Francisco by Wynwood House

15. Torres de Alba Hotel & Suites

Torres de Alba Hotel & Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (587 reviews)
"Good stay here. Breakfast buffet was limited but good. Staff very friendly and helpful."
United States
Nalisa
The price is CA $131
CA $145 total
includes taxes & fees
Nov 6 - Nov 7
Torres de Alba Hotel & Suites

16. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (108 reviews)
"It is a new place, an apartment was in pristine condition. The building is 2 blocks away from the old town."
United States
Arshak Andrew
The price is CA $112
CA $166 total
includes taxes & fees
Oct 8 - Oct 9
Casco View Life Residences

17. Boutique Apartments Panama

Boutique Apartments Panama
3.5 star property
Bella Vista
8.0 out of 10, Very good, (389 reviews)
"Great stay!!!!"
United States
fitz
The price is CA $68
CA $231 total
includes taxes & fees
Oct 18 - Oct 19
Boutique Apartments Panama

18. Marriott Executive Apartments Panama City, Finisterre

Marriott Executive Apartments Panama City, Finisterre
4.0 star property
Bella Vista
8.8 out of 10, Excellent, (770 reviews)
"Front desk staff were very friendly and accommodating. Clear communication throughout my stay. Breakfast varied day to day which was nice. Enjoyed the omelette bar. Overall great location and clean spacious rooms."
United States
Markeisha
The price is CA $162
CA $178 total
includes taxes & fees
Nov 2 - Nov 3
Marriott Executive Apartments Panama City, Finisterre

19. Yoo Panamá by Boutique Apartments

Yoo Panamá by Boutique Apartments
3.5 star property
Bella Vista
8.2 out of 10, Very good, (139 reviews)
"It was a very beautiful property and prime location! All around experience was great!"
United States
Michelle
The price is CA $55
CA $260 total
includes taxes & fees
Nov 3 - Nov 4
Yoo Panamá by Boutique Apartments

20. Spectacular apartment

Spectacular apartment
Bethania
10.0 out of 10, Exceptional, (1 review)
"The host was friendly and did his best to accommodate us' The apartment was spacious, was equipped with all the necessary equipment to cook, and had a nice washer and dryer. Parking provided was safe and secure"
United States
carolyn renee T.
The price is CA $146
CA $196 total
includes taxes & fees
Oct 18 - Oct 19
Spectacular apartment
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Clara Hotel Reviews

Find out more about Santa Clara

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Clara. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Santa Clara?

Yes, there are vacation rentals close to popular attractions in Santa Clara, or you can choose a secluded option if you'd like a relaxing place to stay. Santa Clara is known for its monuments.

What are some of the best vacation home rentals that Santa Clara has to offer?

Downtown Villa with Private Pool & Bar: This vacation home rental outside of Santa Clara offers an outdoor pool, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 8 bedrooms as well as a kitchen with a fridge, a stovetop, and kitchenware, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a garden.

What can I see and do in Santa Clara?

While exploring the area, visit family-friendly sights like Summit Botanical Gardens & Zoo, or get outside and enjoy nature at Culebra Cut. In the larger area, you’ll find Albrook Shopping Mall and Gamboa Rainforest Resort.

What are vacation rentals like in Santa Clara?

Vacation rentals are privately owned properties you can book for several days or longer in Santa Clara. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for families.