Title: Book the Best BUSINESS Hotels in Rochester in 2026 | Expedia.ca [Hotels in Rochester](https://expedia.ca/Rochester-Hotels.d3041.Travel-Guide-Hotels)[Vacation Rentals in Rochester](https://expedia.ca/Rochester-Vacation-Rentals.d3041.Travel-Guide-VacationRentals)[Flights to Rochester](https://expedia.ca/Cheap-Flights-To-Rochester.d3041.Travel-Guide-Flights)[Rochester Car Rentals](https://expedia.ca/Car-Rentals-In-Rochester.d3041.Car-Rental-Guide)[Rochester Vacation Packages](https://expedia.ca/Rochester.d3041.Destination-Travel-Guides) ![Rochester Minnesota; Shutterstock ID 82642243](https://images.trvl-media.com/place/3041/2aa1af3e-4182-4ce9-9fc7-ca2c436d39ff.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Rochester, MN from CA $109 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Rochester Business Hotels Tonight [Dec 11 - Dec 12](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2025-12-11&endDate=2025-12-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 12 - Dec 13](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2025-12-12&endDate=2025-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=3041&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Rochester business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/48e45010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/f4426c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/bba1b373.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/10000/5400/5327/290eee76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Indigo Rochester – Mayo Clinic Area by IHG [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) Downtown Rochester 8.8/10 Excellent (884) "Great room and stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trevor CA $108 CA $124 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Rochester-Hotels-Hotel-Indigo-Rochester-Downtown.h5327.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/d5501184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/fd6d967e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/62a372dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub](https://images.trvl-media.com/lodging/3000000/2190000/2185000/2184971/687d1b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Rochester South - Mayo Area by IHG [](https://www.expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) Rochester 8.8/10 Excellent (1000) "Everything was great !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathryn CA $101 CA $116 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Rochester-Hotels-Comfort-Suites.h2184971.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/7b075080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/9d267d23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/d3281bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/91000000/90620000/90610700/90610605/bde7ad17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Rochester Mayo Clinic Area South [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) Rochester 9.6/10 Exceptional (245) "Very nice motel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jim CA $148 CA $170 total includes taxes & fees Dec 20 - Dec 21 [](https://www.expedia.ca/Rochester-Hotels-Residence-Inn-By-Marriott-Rochester-Mayo-Clinic-Area-South.h90610605.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/c7dc0b32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/34563649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 Queen Bed | Living area](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/5b3222d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/86a7bf04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Rochester South [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) Rochester 9.4/10 Exceptional (307) "The rooms are very nice and the staff is very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roberta CA $95 CA $109 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/d78e621e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/85d1ed51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/f5c13843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/853500/853433/881774df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester [](https://www.expedia.ca/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) Rochester 8.8/10 Excellent (1003) "Clean rooms, friendly staff, good stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Della CA $104 CA $120 total includes taxes & fees Dec 16 - Dec 17 [](https://www.expedia.ca/Rochester-Hotels-AmericInn-By-Wyndham-Rochester-Airport.h853433.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's pool](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/adc84b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/76e5e57e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/dd818bd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) Rochester 7.2/10 Good (1021) "Breakfast was good. The staff was great. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kjirsta CA $97 CA $111 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Serves lunch, dinner, and happy hour](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/96cfed25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Patio Room, 1 King Bed, Pet-Friendly, Non Smoking](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/079e9789.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing, Tub w/Grab bars)](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/f1759bd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Rochester Near Mayo Clinic [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) Rochester 8.2/10 Very good (1131) "Great location and value" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle CA $101 CA $116 total includes taxes & fees Dec 26 - Dec 27 [](https://www.expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/21638bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/6a0aeefd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/9472e74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/60000000/59620000/59619600/59619526/937e6b61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EVEN Hotel Rochester - Mayo Clinic Area by IHG [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) Kutzky Park 9.4/10 Exceptional (956) "Rooms are comfortable and staff was was so professional and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $139 CA $163 total includes taxes & fees Dec 12 - Dec 13 [](https://www.expedia.ca/Rochester-Hotels-Even-Rochester-St-Marys-Area.h59619526.Hotel-Information) ![Indoor pool, open 5:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/b4acd4ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/86063f91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Multiple Beds | Living area](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/c7a0b093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27430000/27426400/27426319/7a948f8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Rochester Mayo Clinic Area [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) Downtown Rochester 9.6/10 Exceptional (542) "Very courteous staff, loved the valet guy!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean CA $236 CA $272 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Rochester-Hotels-Hilton-Rochester-Mayo-Clinic-Area.h27426319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/9694b265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/35ffad98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/9042deaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/40000000/40000000/39999300/39999228/3c209054.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Hotel & Suites - Austin [](https://www.expedia.ca/Rochester-Hotels-Cobblestone-Hotel-Suites-Austin.h39999228.Hotel-Information) Austin 9.0/10 Wonderful (664) "place was great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) joel CA $108 CA $120 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Rochester-Hotels-Cobblestone-Hotel-Suites-Austin.h39999228.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-25&endDate=2025-12-26®ionId=3041&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Rochester Hotel Reviews ![Aspen Suites](https://images.trvl-media.com/lodging/1000000/910000/904700/904615/6c7e0658_y.jpg) ### Aspen Suites 10/10 Excellent "Everything was impeccable. The staff incredible. Amenities incredible. Colton at the desk was extremely professional and courteous to all of the guests. So impressive and he knew all of the guests by there names and remembered what their needs were. Colton is an employee anyone would want at the helm. Also he was so professional serving soup to guests. This hotel hit all of the marks that anyone would look for during their travel. Thank you all so much. Amazing. Chef JSW" [](https://expedia.ca/Rochester-Hotels-Aspen-Suites.h904615.Hotel-Information) ![Spark by Hilton Rochester South](https://images.trvl-media.com/lodging/12000000/11680000/11673200/11673145/w3837h2557x3y3-c2ce9db3_y.jpg) ### Spark by Hilton Rochester South 10/10 Excellent "Hotels was very clean and staff was very friendly. " [](https://expedia.ca/Rochester-Hotels-Spark-By-Hilton-Rochester-South.h11673145.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S](https://images.trvl-media.com/lodging/8000000/7780000/7772100/7772018/569eb353_y.jpg) ### La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S 10/10 Excellent "I have stayed here a couple times in the past. The renovations are spot on. The cleanliness was superb. The staff were very friendly. The roll in shower and hearing impaired room worked out great for my health issues. It was an easy check in online. " [](https://expedia.ca/Rochester-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Rochester-Mayo-Clinic-S.h7772018.Hotel-Information) ![Kahler Inn and Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/180000/171600/171566/e56e7dae_y.jpg) ### Kahler Inn and Suites - Mayo Clinic Area 10/10 Excellent "Staff is alway very polite" [](https://expedia.ca/Rochester-Hotels-Kahler-Inn-And-Suites-Mayo-Clinic-Area.h171566.Hotel-Information) ![Kahler Grand Hotel](https://images.trvl-media.com/lodging/1000000/30000/25600/25516/a12994da_y.jpg) ### Kahler Grand Hotel 10/10 Excellent "Staff was friendly and helpful! Will continue to stay here while at the Mayo, " [](https://expedia.ca/Rochester-Hotels-Kahler-Grand-Hotel.h25516.Hotel-Information) ![AmericInn by Wyndham Rochester Near Mayo Clinic](https://images.trvl-media.com/lodging/1000000/10000/8100/8008/71b6fb30_y.jpg) ### AmericInn by Wyndham Rochester Near Mayo Clinic 10/10 Excellent "Clean room and great staff" [](https://expedia.ca/Rochester-Hotels-Ramada-By-Wyndham-Rochester-Mayo-Clinic-Area.h8008.Hotel-Information) ![Med City Inn & Suites - Mayo Clinic Area](https://images.trvl-media.com/lodging/1000000/10000/4200/4106/821fc05d_y.jpg) ### Med City Inn & Suites - Mayo Clinic Area 10/10 Excellent "I arrived late at night and the young man checking me in was most helpful and friendly (don't always see this at 11 pm!) Very clean and comfortable room, even including a selection of different thicknesses of pillows! (A bonus for those of us who don't like sleeping with our head a foot up in the air...) Excellent breakfast choices." [](https://expedia.ca/Rochester-Hotels-GuestHouse-Rochester.h4106.Hotel-Information) ![Brentwood Inn & Suites](https://images.trvl-media.com/lodging/11000000/10010000/10007700/10007613/d36e6ac3_y.jpg) ### Brentwood Inn & Suites 10/10 Excellent "Good clean room every one helpful only thing for my wife and I it’s hard to keep the room cool for sleeping but that’s a small thing " [](https://expedia.ca/Rochester-Hotels-Brentwood-Inn-Suites.h10007613.Hotel-Information) ![Hampton Inn Rochester-South](https://images.trvl-media.com/lodging/1000000/20000/16600/16522/f90bd051_y.jpg) ### Hampton Inn Rochester-South 10/10 Excellent "Great staff. Shuttle service was convenient and the breakfast was good." [](https://expedia.ca/Rochester-Hotels-Hampton-Inn-Rochester.h16522.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Rochester cost? ### What are the best business-friendly hotels in Rochester? ### How many business-friendly hotels are there in Rochester? ### What are the best cheap business-friendly hotels in Rochester? ### What are the top business-friendly motels in Rochester? ### Are there any family-friendly hotels in Rochester that are also business friendly? ### Are there any 5-star business-friendly hotels in Rochester? ### Why book your business-friendly hotel in Rochester with Expedia? ### How can I find cheap business-friendly hotels in Rochester? ### What is there to do in Rochester near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [4 Star Hotels in Northwest ](https://www.expedia.ca/4Star-Northwest-Rochester-Hotels.s40-n900102874825277440-0.Travel-Guide-Filter-Hotels) - 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