A train crossing a stone bridge over a river, surrounded by lush greenery.

Find Spa Hotels in Perryville, MO from CA $112

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Check availability on Perryville Spa Hotels

This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

Our top choices for Perryville hotels with a spa

Exterior

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
The price is CA $119
CA $126 total
includes taxes & fees
Jul 26 - Jul 27
Drury Inn & Suites Jackson MO
Exterior

Perryville RV Resort

Perryville RV Resort
2.0 star property
Perryville
The price is CA $105
CA $120 total
includes taxes & fees
Jul 9 - Jul 10
Perryville RV Resort
Exterior

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (564 reviews)
The price is CA $168
CA $186 total
includes taxes & fees
Jul 19 - Jul 20
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Free daily breakfast

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (146 reviews)
The price is CA $133
CA $151 total
includes taxes & fees
Jul 26 - Jul 27
Tru By Hilton Cape Girardeau
Exterior

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (795 reviews)
The price is CA $132
CA $142 total
includes taxes & fees
Jul 22 - Jul 23
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Exterior

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (605 reviews)
The price is CA $143
CA $164 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Perryville by IHG
Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.4 out of 10, Very good, (403 reviews)
The price is CA $124
CA $138 total
includes taxes & fees
Jul 14 - Jul 15
Baymont by Wyndham Chester IL
Exterior

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very good, (1,005 reviews)
The price is CA $98
CA $112 total
includes taxes & fees
Aug 3 - Aug 4
Super 8 by Wyndham Perryville
Porch

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (305 reviews)
The price is CA $124
CA $136 total
includes taxes & fees
Jul 11 - Jul 12
Madison Inn Lodge
Free buffet breakfast

Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (412 reviews)
The price is CA $173
CA $192 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express Hotel & Suites Sparta by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Perryville

Pool
Breakfast included

Top Perryville Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Perryville?
Treat yourself to some pampering and book a hotel with a spa. Check out the natural parks in Perryville - worth a picture or two! Take part in recreational activities such as golfing during your vacation. Spa hotels are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Perryville?
Enjoy all that Perryville has to offer and visit National Shrine of Our Lady of the Miraculous Medal, Mark Twain National Forest, and Mississippi River. If you have a little extra time during your trip, you might want to check out Perryville Country Club and Saint Marys Lake.
What is a Perryville spa hotel?
Spa hotels in Perryville feature on-site spas which offer services such as massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

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