Your Penonome Vacation

Take the hassle out of organizing your next amazing adventure with a Penonome vacation package. Whether you're visiting for its history, food or something else, this city offers endless possibilities for fun. Fill your trip to Penonome with tours of some of its top attractions. First stop? Make a beeline for 8 de Diciembre Park. Whoever you're taking time off with and whatever the size of your budget, your ultimate Penonome vacation is just a few clicks away with Expedia.

Top Penonome Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Megapolis Hotel Panamá

San Francisco

CA $1,182

per person

Aug 21 - Aug 26

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

8.4/10 Very Good! (1,553 reviews)

This was absolutely fabulous! The buffet in the mornings were the best part to start your day with fresh omelets and freshly squeezed juices with all of the bells and whistles of a buffet. I would definitely come back to stay.

Reviewed on Jun 10, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

CA $1,807

per person

Jul 25 - Aug 1

found 6 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

9.2/10 Wonderful! (1,011 reviews)

We thoroughly enjoyed our stay. Relaxing, clean and sophisticated vibe there. Central location can’t be beat. So comfortable! We liked the breakfast buffet as well. Staff was friendly. Would stay again! Very pleased :)

Reviewed on Jun 7, 2026

Riande Aeropuerto Hotel & Casino

CA $1,479

per person

Jul 25 - Aug 1

found 6 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

8.4/10 Very Good! (1,825 reviews)

The pool area is very nice

Reviewed on Jun 12, 2026

Las Americas Golden Tower Panama

San Francisco

CA $1,542

per person

Jul 25 - Aug 1

found 6 hours ago

Roundtrip flight included

Montreal Metropolitan Airport (YHU) to Panama City (PTY)

9/10 Wonderful! (1,023 reviews)

Todo fue excelente desde el servicio, las vistas y las instalaciones. Lo único que podría dejar como observación es que la mampara de los baños es muy transparente y no me hospedaba en pareja si no con mi hermano así que fue un tanto incómodo. De ahí todo un 10/10

Reviewed on Jun 11, 2026

Casa Mallet by Wynwood House

Casco Viejo

CA $1,888

per person

Jul 20 - Jul 27

found 1 day ago

Roundtrip flight included

Montreal (YMQ) to Panama City (PTY)

9.8/10 Exceptional! (27 reviews)

In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.

Reviewed on Mar 12, 2026

Ready to book your vacation to Penonome?

Choose your dates

Penonome Hotel Deals

Hotel Coclé

Via Interamericana Penonome Cocle

Fully refundableReserve now, pay when you stay

CA $100

CA $110 total

Jun 21 - Jun 22

includes taxes & fees

8.6/10 Excellent! (244 reviews)

"en la recepcion les falta mas amabilidad. podrian ser mas amables. lo que me encanto fue la nueva cafeteria hermosa."

Reviewed on Jun 4, 2026

Hotel Dimashq

Avenida Damian Carles Penonomé Provincia de Coclé

CA $56

CA $62 total

Jul 3 - Jul 4

includes taxes & fees

2/10 (1 review)

"Pongan claramente la ubicación y no hagan como si estuviera en el valle"

Reviewed on May 17, 2026

Hotel Guacamaya

Carr. Interamericana Penonome Provincia de Coclé

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See all 305 properties in Penonome

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.