Panama Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

Choose two or more items and save on your trip:

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    Save up to CA $775 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Top vacation destinations in Panama

Top Panama Vacation Deals

Royal Decameron Panama Plus - All Inclusive
Royal Decameron Panama All Inclusive
Central Hotel Panama Casco Viejo
Dreams Playa Bonita Panama - All Inclusive
Los Establos Boutique Resort- All Inclusive
Prices and availability subject to change. Additional terms may apply.

Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 2,530 hotels available here starting at CA $156 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?

Your Panama Vacation Itinerary

  • Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

  • Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

  • Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

  • Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

  • If you’ll be spending most of your time in the nation’s capital, check out ourPanama City Vacation Packages.

  • Want to really experience the carefree vibe of this Latin American gem? Book one of ourPanama All Inclusive Resortsand say adios to vacation planning stress.

Panama Hotel Deals

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is CA $156 per night from Mar. 31 to Apr. 1
CA $156
CA $171 total
includes taxes & fees
Mar 31 - Apr 1
9/10 Wonderful! (2,125 reviews)
"Staff was very helpful in every way. They gave directions, changed money, supplied extra towels"

Reviewed on Mar. 15, 2024

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive
Dreams Playa Bonita Panama - All Inclusive
4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is CA $330 per night from Apr. 1 to Apr. 2
CA $330
CA $330 total
includes taxes & fees
Apr 1 - Apr 2
7.4/10 Good! (924 reviews)
"It was clean and beautiful. Staff was pleasant. Room was cleaned and mopped everyday. Overall a wonderful experience."

Reviewed on Mar. 4, 2024

Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport, an IHG Hotel
Crowne Plaza Panama Airport, an IHG Hotel
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
The price is CA $163 per night from Mar. 24 to Mar. 25
CA $163
CA $179 total
includes taxes & fees
Mar 24 - Mar 25
8.2/10 Very Good! (1,753 reviews)
"Nice overnight hotel with clean rooms, friendly staff. Easy to get to from airport."

Reviewed on Mar. 16, 2024

Crowne Plaza Panama Airport, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore other types of vacation packages

Frequently asked questions

How much does a Panama vacation package cost?
Custom build your Panama vacation package from a low CA $1,307. Choose from any combination of rental cars, flights and hotels to pull together the trip you’ve been dreaming about. Remember to add on some activities and experiences!
How do I get a cheap travel package to Panama?
One of the easiest ways to save cash (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we’ve got them all. Select the combination that suits you and watch your savings stack up. Of course, a package deal is never one-size-fits-all. That’s why we offer over 550 airlines and 1,000,000 hotels worldwide, which lets you customize your Panama vacation.
Where should I stay in Panama?
Panama City is a great place to visit. It draws in many visitors who come to check out its biggest sights, such as Bridge of the Americas and Miraflores Locks.
What are the top hotels in Panama?
When it comes to hotels in Panama City, Hotel Riu Plaza Panama and Crowne Plaza Panama Airport, an IHG Hotel are two terrific options. If you’re also visiting Bocas del Toro, Playa Tortuga Hotel Beach And Resort and Azul Paradise will make you feel at home.
How far in advance should I book my Panama vacation?
It’s difficult to pick the ideal time for airfares, but we usually say the earlier, the better. Most international journeys on Expedia become available up to 12 months in advance. If you’re booking last minute, fear not. Discounted prices appear from time to time just weeks before departure dates.
What does an Expedia Panama travel package include?
Hotels, rental cars and flights, or any combination of them — it’s up to you! Whether you’re venturing to Panama with the kids or traveling solo, there’s a package to fit your budget and style. Once you’ve made your booking, why not add on one or two tours or activities?
What should I know before booking a Panama travel package?
A travel package can be customized for your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Rental cars, hotels and flights — come up with a combination that suits your plans.
Can I choose my airline with a Panama Expedia vacation package?
Yes — and it’s simple too. Expedia has access to more than 550 partner airlines all over the world. Our packages give you the flexibility to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Panama vacation package?
Because we know life is full of surprises, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you’ve made your booking in the last 24 hours, you may be able to change or cancel it for free. Your airline, hotel or car rental company may impose a fee if you made your booking a while ago.

Discover the most popular places to visit in Panama

What to do in Panama

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.