- Better togetherSave up to CA $775 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
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Top vacation destinations in Panama
Top Panama Vacation Deals
Royal Decameron Panama Plus - All Inclusive
Reviewed on Mar. 17, 2024
Central Hotel Panama Casco Viejo
Reviewed on Mar. 12, 2024
Dreams Playa Bonita Panama - All Inclusive
Reviewed on Mar. 18, 2024
Los Establos Boutique Resort- All Inclusive
Reviewed on Feb. 4, 2024
Panama Vacation
While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.
Panama Hotel + Flights
Expedia has 2,530 hotels available here starting at CA $156 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavours like ceviche?
Your Panama Vacation Itinerary
Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colourful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.
Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.
Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.
Panama Information
Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.
If you’ll be spending most of your time in the nation’s capital, check out ourPanama City Vacation Packages.
Want to really experience the carefree vibe of this Latin American gem? Book one of ourPanama All Inclusive Resortsand say adios to vacation planning stress.
Panama Hotel Deals
Reviewed on Mar. 15, 2024
Reviewed on Mar. 4, 2024
Reviewed on Mar. 16, 2024
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Frequently asked questions
Discover the most popular places to visit in Panama
Playa Blanca
Nothing says vacation like spending a lazy day at Playa Blanca, a popular beach in Rio Hato. Amble around this romantic area's seaside or experience its entertainment venues.
Multiplaza Pacific Mall
During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.