Mission Valley Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to CA $1,096 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Mission Valley

Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites San Diego Seaworld
The Sofia Hotel
InterContinental San Diego by IHG
Sand Castle Inn
Margaritaville Hotel San Diego Gaslamp Quarter

Where to stay in Mission Valley

Find the best Mission Valley areas and neighborhoods for the activities you enjoy most. Learn more about Mission Valley

Mission Valley Hotel Deals

Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $130 per night from Aug 25 to Aug 26
CA $130
CA $149 total
Aug 25 - Aug 26
includes taxes & fees
8/10 Very Good! (1,963 reviews)
"We love this hotel and stay here often. The pool and hot tub are great and there are fire pits for night time hangs by the pool. There’s a great lil bar and restaurant there. Staff is always warm and friendly. Next door to golf course, restaurants, shopping, etc"

Reviewed on Aug. 14, 2025

Handlery Hotel
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from Sep 1 to Sep 2
CA $173
CA $199 total
Sep 1 - Sep 2
includes taxes & fees
8/10 Very Good! (1,903 reviews)
"Cleanliness could have been better but staff was great"

Reviewed on Aug. 16, 2025

Hilton San Diego Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Aug 25 to Aug 26
CA $176
CA $202 total
Aug 25 - Aug 26
includes taxes & fees
8.4/10 Very Good! (1,501 reviews)
"Very nice stay. Will definitely stay here anytime I come back to SD."

Reviewed on Aug. 16, 2025

Sheraton Mission Valley San Diego Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Valley vacation package cost?
From as low as CA $631. Yes, you read that correctly. Our Mission Valley vacation packages are the best way to make your budget last longer. Bundle your preferred flights, hotels and rental car and explore this top destination.
How do I get a cheap travel package to Mission Valley?
Booking a hotel and flight together with Expedia won't just save precious time — it'll save you cash too. A Mission Valley vacation package makes it simple to arrange the ideal trip. With more than 550 airlines across the world to pick from, finding flights that suit your busy schedule won't be a hassle. Not only that, we have over 1,000,000 properties globally to take your pick of. Now that's what you call choice. No matter who you are, Expedia puts the world within your reach.
Where should I stay in Mission Valley?
Most people who travel to Mission Valley put both San Diego Zoo and Balboa Park on their must-see lists. Why not book a hotel close to one of these fantastic attractions?
What are the top hotels in Mission Valley?
Lock in a room at Secluded, Charming And Unique Spacious Apartment Excellent Central Location. It's one of this area's most in-demand hotels. Another highly rated option in Mission Valley is Extended Stay America Suites San Diego Fashion Valley.
How far in advance should I book my Mission Valley vacation?
Savvy travelers book early. Air carriers usually release flights up to a year prior to departure, and this is a perfect opportunity to land some of the cheapest prices. Just been told you need to take all your vacation days next month? Don't fret. Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Mission Valley travel package include?
Travel packages include hotels, rental cars and flights, but you can combine any of them to create your dream Mission Valley getaway. You can also add on fun things like activities and tours once you've made your booking. You're in control! When you bundle your bookings with Expedia, you'll score deals you won't find elsewhere.
What should I know before booking a Mission Valley travel package?
When you book your hotels, flights and car rentals together, you'll walk away with awesome discounts. Whether you're organizing a mountain getaway in a cabin or prefer to stay in a ritzy city hotel, Expedia will help make it happen.
Can I choose my airline with a Mission Valley Expedia vacation package?
Yes, of course. We have more than 550 airline partners around the world, so opt for the carrier that best suits your budget and travel needs.
If I'm not able to travel, can I cancel my Mission Valley vacation package?
If your travel plans in Mission Valley have changed, it's a relief to know that you can cancel or amend your booking. If you booked less than 24 hours ago, you may be eligible for a refund. If your booking is older than that, your hotel, airline or car rental company may charge a cancellation fee. For more details, visit our Customer Service Portal.

Discover the most popular places to visit in Mission Valley

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.