Title: Matlacha Isles-Matlacha Shores Inns from CA $219 | Expedia.ca [Matlacha Isles-Matlacha Shores Travel Guide](https://expedia.ca/Matlacha-Isles-Matlacha-Shores.dx553248635975849540)[Hotels in Matlacha Isles-Matlacha Shores](https://expedia.ca/Matlacha-Isles-Matlacha-Shores-Hotels.d553248635975849540.Travel-Guide-Hotels)[Vacation Rentals in Matlacha Isles-Matlacha Shores](https://expedia.ca/Matlacha-Isles-Matlacha-Shores-Vacation-Rentals.d553248635975849540.Travel-Guide-VacationRentals)[Matlacha Isles-Matlacha Shores Car Rentals](https://expedia.ca/Car-Rentals-In-Matlacha-Isles-Matlacha-Shores.d553248635975849540.Car-Rental-Guide)[Matlacha Isles-Matlacha Shores Vacation Packages](https://expedia.ca/Matlacha-Isles-Matlacha-Shores.d553248635975849540.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Inns in Matlacha Isles-Matlacha Shores from CA $219 ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-10-03&endDate=2025-10-05&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-10-10&endDate=2025-10-12&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-10-24&endDate=2025-10-26&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Nov 21 - Nov 23](https://www.expedia.ca/Hotel-Search?regionId=553248635975849540&startDate=2025-11-21&endDate=2025-11-23&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Browse Select Matlacha Isles-Matlacha Shores Inns ## Our top choices for Matlacha Isles-Matlacha Shores inns ![Exterior](https://images.trvl-media.com/lodging/106000000/105190000/105185200/105185190/6133fc8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cottage, Lanai, Garden View | Private kitchen](https://images.trvl-media.com/lodging/106000000/105190000/105185200/105185190/89dd173c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cottage, Lanai, Garden View | Living area](https://images.trvl-media.com/lodging/106000000/105190000/105185200/105185190/5a49a2df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Cottage, Lanai, Garden View | Living area](https://images.trvl-media.com/lodging/106000000/105190000/105185200/105185190/6fcbb8db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Driftwood Inn Sanibel 10/10 Exceptional (5) "Great place to stay on sanibel" CA $354 CA $725 total includes taxes & fees Sep 24 - Sep 25 [](https://www.expedia.ca/Sanibel-Hotels-Driftwood-Inn.h105185190.Hotel-Information) ![Standard Studio (HoneyBee) | Private kitchen](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/de0b30c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Studio (Swan) | Living area](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/5326882b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Studio (Turtle)](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/c966b13e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Studio (HoneyBee)](https://images.trvl-media.com/lodging/113000000/112940000/112934500/112934495/d570642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TriLuxe Inn & Studios Iona 7.8/10 Good (17) "Everything was great, will definitely be coming back" CA $156 CA $219 total includes taxes & fees Sep 28 - Sep 29 [](https://www.expedia.ca/Fort-Myers-Hotels-TriLuxe-Inn-Studios.h112934495.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-07&endDate=2025-10-08®ionId=553248635975849540&adults=2&lodging=INN&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMatlacha-Isles-Matlacha-Shores-Inns.d553248635975849540-aaInns.Travel-Guide-Accommodation)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMatlacha-Isles-Matlacha-Shores-Inns.d553248635975849540-aaInns.Travel-Guide-Accommodation) ## Top Matlacha Isles-Matlacha Shores Hotel Reviews ![DiamondHead Beach Resort](//images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "We had an amazing stay at DiamondHead Beach Resort! Our beachfront room overlooked the Gulf, and the views were absolutely stunning. We barely left the resort because everything we needed was right there—beautiful beach access, a great pool area, and delicious food and drinks. The staff was equally amazing, always friendly and attentive, which made our stay even more enjoyable. It was the perfect relaxing getaway, and we can’t wait to come back" [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Sanibel Island Beach Resort](//images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Quick trip to relax. Perfect location right on the beach! Several different room views available- I would choose beach view next time but my room was just perfect. Mid week was nice and quiet, really was just what I needed!" [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Lani Kai Beachfront Resort](//images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "The area is still recovering from hurricane Ian. Most places are still rebuilding. Lani Kai has come along way still has the fantastic beach nice rooms good food can't wait until the roof top bar and restaurant opens their getting close. Hopefully on our next stay. Our get-away " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Margaritaville Beach Resort Fort Myers ](//images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg) ### Margaritaville Beach Resort Fort Myers 10/10 Excellent "Great stay, accommodations, location" [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](//images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "Wonderful " [](https://expedia.ca/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Edison Beach House](//images.trvl-media.com/lodging/12000000/11760000/11753200/11753200/fb0b7d7c_y.jpg) ### Edison Beach House 10/10 Excellent "I loved that it was a studio like apt. that was fully stocked with all of the kitchen supplies. We were able to go grocery shopping and didn't have to eat out all of the time. " [](https://expedia.ca/Fort-Myers-Hotels-Edison-Beach-House.h11753200.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](//images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Welcoming front desk. " [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Pink Shell Beach Resort and Marina](//images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Beautiful view from every room. Adult pool solidified my decision and is perfect. Wish the bar was a better “scene” but enjoyed the pizza. Most evenings spent on our lanai relaxing. Will most definitely stay there again. " [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Comfort Inn & Suites Airport](//images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/2deb021c_y.jpg) ### Comfort Inn & Suites Airport 10/10 Excellent "It’s a great place for short term trip. The breakfast was good and the Front desk agent Abreu was very great! She was really nice " [](https://expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) ## Find out more about Matlacha Isles-Matlacha Shores ## Matlacha Isles-Matlacha Shores Inns information | Number of reviews | 22 | | --- | --- | | Accommodation | 2 Inns | | Lowest Price | CA $219 | | Highest Price | CA $725 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - More ways to book - [2 Star Hotels in Burnt Store](https://www.expedia.ca/2Star-Burnt-Store-Cape-Coral-Hotels.s20-n553248635976481229-0.Travel-Guide-Filter-Hotels) - [Motels in Alden Pines](https://www.expedia.ca/Alden-Pines-Motels.d553248635976474573-aaMotels.Travel-Guide-Accommodation) - [Pet-Friendly Hotels in Burnt Store](https://www.expedia.ca/Burnt-Store-Cape-Coral-Hotels-Pet-Friendly-Hotel.0-n553248635976481229-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Burnt Store Hotels](https://www.expedia.ca/Burnt-Store-Cape-Coral-Hotels.0-n553248635976481229-0.Travel-Guide-Filter-Hotels) - 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