Title: 10 Best Hotels in Matlacha Isles, Cape Coral for 2026 | Expedia.ca [Vacation Rentals in Cape Coral](https://expedia.ca/Cape-Coral-Vacation-Rentals.d6521.Travel-Guide-VacationRentals)[Flights to Cape Coral](https://expedia.ca/Cheap-Flights-To-Cape-Coral.d6521.Travel-Guide-Flights)[Things to do in Cape Coral](https://expedia.ca/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities)[Matlacha Isles Car Rentals](https://expedia.ca/Car-Rentals-In-Matlacha-Isles.d553248635976471942.Car-Rental-Guide)[Matlacha Isles Vacations](https://expedia.ca/Matlacha-Isles.d553248635976471942.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 19 - Jan 20](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2026-01-19&endDate=2026-01-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 20 - Jan 21](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2026-01-20&endDate=2026-01-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=553248635976471942&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Matlacha Isles hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/bbf3ce91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio with Two Doubles, Beachfront, Balcony](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/3202bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) 23.2 km from Matlacha Isles 9.0/10 Wonderful (1,138 reviews) "The breakfast was good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ileana CA $258 CA $319 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/2c59b397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, Kitchen, Pool View | Living area](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/763b4722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kayaking](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/94b7632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/8bc2b39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach [](https://www.expedia.ca/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) 20.4 km from Matlacha Isles 8.8/10 Excellent (1,005 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea CA $160 CA $178 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/46330a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/d3248701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/54014b0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park [](https://www.expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) 28 km from Matlacha Isles 8.0/10 Very good (1,537 reviews) "Great little hotel. Rooms and common areas look like they were recently renovated, everything was very clean and the staff was great. Thanks for the excellent stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Geoffrey CA $124 CA $138 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/2deb021c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/eec3b567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/a683180f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/06cf7d58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Fort Myers Airport [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) 27.9 km from Matlacha Isles 8.8/10 Excellent (1,117 reviews) "Comfortable rooms and beds, good breakfast and easy access to baseball parks." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier CA $162 CA $180 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/9c00e0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/ea10bb34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/7fb404a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/824d933b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Punta Gorda/Port Charlotte [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) 28.9 km from Matlacha Isles 8.4/10 Very good (1,161 reviews) "The room was excellent and the staff were very friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronnie CA $149 CA $167 total includes taxes & fees Jan 21 - Jan 22 [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/a702090f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/54b129e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/6a1456e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/f37d87d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Fort Myers East I-75 [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) 24.8 km from Matlacha Isles 9.6/10 Exceptional (381 reviews) "Very nice receptionist, and the room is great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn CA $188 CA $209 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/7dc3b2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/37bd8ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/1ba88bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/a5e914cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Ft. Myers [](https://www.expedia.ca/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) 19.3 km from Matlacha Isles 7.6/10 Good (1,153 reviews) "Clean room, fast and friendly, quiet and convenient " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer Jean CA $123 CA $138 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/3bf7e12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/01114515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/0afa75e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/35ad9ea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Fort Myers - Cape Coral [](https://www.expedia.ca/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) 18.2 km from Matlacha Isles 7.2/10 Good (167 reviews) "The service at the front desk was exceptional, the new manager is doing an amazing job!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandro CA $123 CA $138 total includes taxes & fees Jan 24 - Jan 25 [](https://www.expedia.ca/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) ![Floating Coconut Cottage Houseboat | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/1830d2aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/0badd225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 9:30 PM, free cabanas, sun loungers](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/bf04ece4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/85d353d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Resort & Marina [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) 20.3 km from Matlacha Isles 8.6/10 Excellent (923 reviews) "Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $329 CA $367 total includes taxes & fees Feb 19 - Feb 20 [](https://www.expedia.ca/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/693ea816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a638e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) 17 km from Matlacha Isles 7.8/10 Good (1,004 reviews) "Great service, location and facility " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Franca CA $125 CA $139 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/9706f761.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/04c53735.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/5c0dd382.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed Studio w/ Sofa-Bed Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/ca216cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Fort Myers Cape Coral [](https://www.expedia.ca/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) 18.4 km from Matlacha Isles 7.6/10 Good (214 reviews) "Clean room and staff was excellent " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) SURINDER CA $119 CA $154 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f97bdde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) 22.7 km from Matlacha Isles 9.2/10 Wonderful (1,545 reviews) "Nice room, great location on the beach. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa CA $384 CA $463 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/5f870412.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/d9380a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/7cc18ae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/42212932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Fort Myers Inn & Suites [](https://www.expedia.ca/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) 20.8 km from Matlacha Isles 8.8/10 Excellent (1,135 reviews) "Clean room, old property and fresh, varied options for breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) supriya CA $149 CA $166 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/de6b5b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d96dd9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d3615161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/3ed2496c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Punta Gorda by IHG [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) 28.8 km from Matlacha Isles 9.4/10 Exceptional (1,002 reviews) "Clean safe hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) suzanne CA $198 CA $222 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) ![Free continental breakfast on weekdays](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/dce1fc55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/c6ebb5bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/70be5c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/fa977bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Fort Myers - Colonial Blvd [](https://www.expedia.ca/Fort-Myers-Hotels-Hampton-Inn-Suites-Fort-Myers-Colonial-Blvd.h1661939.Hotel-Information) 21 km from Matlacha Isles 9.4/10 Exceptional (1,004 reviews) "Great place to stay, will be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $199 CA $222 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Fort-Myers-Hotels-Hampton-Inn-Suites-Fort-Myers-Colonial-Blvd.h1661939.Hotel-Information) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/300000/297100/297037/7da2f9ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/300000/297100/297037/2ab04080.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/300000/297100/297037/5f13a421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/300000/297100/297037/13a592cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Fort Myers Northeast [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Fort-Myers-Northeast.h297037.Hotel-Information) 25.8 km from Matlacha Isles 7.8/10 Good (683 reviews) "Nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carole CA $164 CA $183 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Comfort-Inn-Fort-Myers-Northeast.h297037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/ffbd89e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/a6afb300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/d477de54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/ed9fe2ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Fort Myers Cape Coral [](https://www.expedia.ca/Fort-Myers-Hotels-Courtyard-By-Marriott-Fort-Myers-Cape-Coral.h22386.Hotel-Information) 20.4 km from Matlacha Isles 8.2/10 Very good (1,003 reviews) "Great service, would stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $174 CA $194 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Fort-Myers-Hotels-Courtyard-By-Marriott-Fort-Myers-Cape-Coral.h22386.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/c2f92274.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/105102fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/3d373ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/da383170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Punta Gorda [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Knights-Inn-Punta-Gorda.h50640.Hotel-Information) 28.5 km from Matlacha Isles 7.2/10 Good (956 reviews) "Yes" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John CA $119 CA $134 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Knights-Inn-Punta-Gorda.h50640.Hotel-Information) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/18900/18848/06c908cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/18900/18848/31861d8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18900/18848/33ba5286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18848/63af51b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Fort Myers Airport [](https://www.expedia.ca/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers-Airport.h18848.Hotel-Information) 27.1 km from Matlacha Isles 7.4/10 Good (1,002 reviews) "Was " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $93 CA $103 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers-Airport.h18848.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/6e0e9983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/c629410b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/60e66959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/2e281d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boca Grande Hotel [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Boca-Grande-Hotel.h17238826.Hotel-Information) 28.8 km from Matlacha Isles 8.8/10 Excellent (591 reviews) "The staff are exceptional. Victoria was so helpful and Margarita went above and beyond. I am a single woman travelling alone and felt very well taken care of. I would highly recommend this property." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diana CA $215 CA $241 total includes taxes & fees Jan 29 - Jan 30 [](https://www.expedia.ca/Port-Charlotte-Charlotte-Harbor-Hotels-Boca-Grande-Hotel.h17238826.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-03&endDate=2026-02-04®ionId=553248635976471942&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Matlacha Isles Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. - Pelican - Caloosahatchee - Yacht Club - Mariner - Hancock ![](https://mediaim.expedia.com/destination/9/350251ac0d9ccc7ca1cb30ed3f0f1512.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/6787174d3f020d364df18c0504ee6a50.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0db9ea0d958f3eddc014a2724a550e04.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/f6aa46e3ec22aaa67f528102c099f4db.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0383eed5f73bce5b51600c8b78edb8e2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976481346) ![Pelican map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oacaDfs%7BsNq_C_z%40an%40al%40m%7B%40sH%7Bo%40dPrGsaGz%40%7DqClLse%40%7C%40se%40fdIbAdSjDhvAeAhg%40t%60B%7CX%7EmEvDdeCswCxcBa%7CAha%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=E70lew0W6sFXzCxHzRLVFKaS8Mg=) ### Pelican If you're spending some time in Pelican, Tarpon Point and Chabad Jewish Center are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976481346) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496945-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496204-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496304-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496233-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496139-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635975748682) ![Caloosahatchee map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_l_aDbxisNce%40ImL%7DEg%60Ah%40uvGX%7D%40oaKhPcAlh%40%60nAnc%40dLxl%40qG%7Es%40b%5Bl%5EiGpl%40%60%5D%60PgJnPzZfJvc%40lj%40%7ETx%7E%40vFyBra%40sMlMiPd%60ApPlx%40oFjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cya_maxw6zlgfysES9DHBgO1unY=) ### Caloosahatchee If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635975748682) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976659287) ![Yacht Club map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wo%60aDlwisN%7DGeBsb%40s%5BwJe%5EwIeNzKeXJaI%60HqMH%7D_%40oS%40BuVjEEAwCtLNhCcKhHzDlPbEhOzGxKlC%7EG%7B%40hb%40xAWhKeL%7EViP%60w%40cAdo%40nKvXq%40hFgd%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=9v6IXRj89bAFRtqo7x5Ob4JRxkI=) ### Yacht Club While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Dolphin Marina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976659287) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976470523) ![Mariner map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:etqaDpkssN_oMcA%3FalFkd%40kmAhe%40%3FNgd%40viGlBxHzCfg%40%3Fr%5EgQ%7EeAx%7DClc%40n_BrG%60k%40%7D%40j%60A&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=4CJoAD0sRorEN_B-6JMiJBcI87w=) ### Mariner While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976470523) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495865-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496727-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496600-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/26729640c04cf35e3216cbbc607fc1c6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/2774ef6de242fcb260ae5796be4d6871.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976420438) ![Hancock map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oyraDxtmsN_qFusOp%40mwEi%40gBjy%40oaAvI%7EKm%40tPbe%40%60f%40fj%40uGYdI%7BPfH_BnOvJ%7CHxNmH%7ERe%40jBrDyWjUxHzu%40xNlGv%5D%7EBrIfHv_%40lx%40v%5BfLx%60%40bd%40xQhH%60FhIbn%40wGb%5Dm%40hCmGph%40cL%7CCvyF%60%40%7CsFgqA%3FaN%7EAax%40CcNj%40%7B_%40rHuYvK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=iSHUTH5d48PG0kePXw5a0CSgbnA=) ### Hancock While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976420438) ## Top Matlacha Isles Hotel Reviews ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "The room was clean and the view of the beach, ocean and sunsets were great! Staff was polite and helpful. " [](https://expedia.ca/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Margaritaville Beach Resort Fort Myers ](https://images.trvl-media.com/lodging/96000000/95130000/95127000/95126992/w3998h2821x0y0-a77e6574_y.jpg) ### Margaritaville Beach Resort Fort Myers 10/10 Excellent "Loved it" [](https://expedia.ca/Fort-Myers-Beach-Hotels-Margaritaville-Beach-Resort-Fort-Myers.h95126992.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Amazing resort! The view from our room was gorgeous inside and out. The entire resort was very clean from the room to the pools to the dining. The breakfast offered something for everyone (omelets, pancakes, waffles, fruit, potatoes, yogurt, cereal, juice and much more). The staff goes out of their way to make everything perfect. We will definitely be back!" [](https://expedia.ca/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Room was clean. People were very friendly. I only wish there was water available in the lobby and not just coffee and tea." [](https://expedia.ca/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Good" [](https://expedia.ca/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "The staff was very courteous. " [](https://expedia.ca/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "Such a fun place to stay and the beds were comfortable! " [](https://expedia.ca/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Baymont by Wyndham Fort Myers Central](https://images.trvl-media.com/lodging/1000000/30000/23400/23367/7ff8face_y.jpg) ### Baymont by Wyndham Fort Myers Central 10/10 Excellent "Nice room, " [](https://expedia.ca/Fort-Myers-Hotels-La-Quinta-Inn-By-Wyndham-Fort-Myers-Central.h23367.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Clean, awesome view" [](https://expedia.ca/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ## Frequently asked questions ### What is Matlacha Isles like? ### How many hotels will I be able to find in the Matlacha Isles area? ### If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund? ### What are the top things to see and do in Matlacha Isles? ## Explore a world of travel with Expedia - 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