10 Best Hotels in Mackenzie, St. Louis for 2026

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Where to stay in Mackenzie

Find the best Mackenzie areas and neighborhoods for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Gateway Arch or Busch Stadium might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

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An ornate hall with arched ceilings and intricate patterns.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

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Top Mackenzie Hotel Reviews

Moonrise Hotel

8/10 Good

"The hotel is beautiful, the beds and pillows are super comfortable, the rainfall shower head is magnificent and the parking is free. The rooftop terrace is outstanding with excellent music and the breakfast at the restaurant inside is excellent. However, it’s cashless. The restaurant isn’t, but I somehow ended up with charges to my credit card from there and the hotel that were unauthorized. My other half made the mistake of going downstairs for a smoke and grabbed a soda on his way back in. He gave the guy at the front desk cash, which he accepted, and was told nothing else. Another time a woman “gave” him two drinks and told him “not to worry about it” when he offered her cash. The other guy took it why would he think any differently. I didn’t know anything until I saw the charges on my card. Why accept the money and charge my room? Why let him take the drinks and say “don’t worry about it” only to charge my room? Why not simply state “we’re cashless?” Won’t be staying here again or recommending this place to anybody because of dishonest employees. It’s terrible because I stay in A LOT of hotels and I LOVED everything else."

Pear Tree Inn St. Louis Airport

8/10 Good

"We stayed here just before July 4th weekend. The staff was absolutely fantastic! Top level customer service. Everyone from the manager to wonderful ladies working the breakfast to the janitor and housekeeping would say hello or good morning. The house keeping arranged my daughter's stuffed animals on the bed and she loved it. The only little issue was our shower kept running slowly. I am sure if we would have let them know they would have switched us rooms. But we decided to just deal with it. We travel a lot and have had much worse customer experience at places twice the price. We absolutely will be staying here on our trips to st louis."

Frequently asked questions

What's it like in Mackenzie?

Travelers will be sure to find plenty to entertain them in St. Louis's Mackenzie neighborhood.

If I need to cancel my hotel reservation in Mackenzie, will I receive a refund?

Yes! Most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer in Mackenzie.

What is there to do in this St. Louis neighborhood?

Lindenwood Park, Repertory Theatre of St. Louis, and River des Peres Greenway Trailhead are just a few of the places to visit in and around Mackenzie. While you're out sightseeing, The Focal Point and Webster Groves Tennis Center are a couple of additional sights to visit in St. Louis.

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Hotels in Mackenzie, St. Louis

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Our top choices for Mackenzie hotels

Pear Tree Inn St. Louis Airport

Wingate by Wyndham St. Louis Airport

Drury Inn & Suites St. Louis Airport

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Hyatt Select St. Louis Airport

River City Casino & Hotel

Best Western St. Louis Inn

Hampton Inn By Hilton St Louis Airport

The Wildwood Hotel

Renaissance St. Louis Airport Hotel

Pear Tree Inn St. Louis Arnold

Wingate by Wyndham St. Louis/Fenton Route 66

Drury Inn & Suites Southwest St. Louis

Holiday Inn Express & Suites St Louis Airport by IHG

Hilton St. Louis Frontenac

Hollywood Casino & Hotel St. Louis

The Principal Hotel

Drury Plaza Hotel St. Louis Chesterfield

Super 8 by Wyndham St Charles

Clayton Plaza Hotel & Extended Stay

Where to stay in Mackenzie

Downtown St. Louis

Clayton

Creve Coeur

Central West End

Downtown West

Top Mackenzie Hotel Reviews

Moonrise Hotel

Frequently asked questions

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