Search Apartment Rentals in Lake City

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Find vacation rentals that suit your style

Apartment image
Apartments
Apartments
Cottage image
Cottages
Cottages

Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Lake City

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

1. The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.6 out of 10, Exceptional, (1,005 reviews)
"Excellent stay. A little overpriced for the area. But nice hotel."
United States
Winston
The price is CA $154
CA $173 total
includes taxes & fees
Dec 8 - Dec 9
The Inn at the Crossroads
A spacious lobby with a chandelier, seating area, and a reception desk.

2. Quality Inn & Suites Lake City

Quality Inn & Suites Lake City
2.5 star property
Lake City
7.2 out of 10, Good, (191 reviews)
"Not the best hotel. Bathroom was dirty."
United States
Vajannise
The price is CA $121
CA $135 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn & Suites Lake City
A spacious lobby with a large seating area, a decorative ceiling light, and a view of the outdoors.

3. Days Inn by Wyndham Lake City

Days Inn by Wyndham Lake City
2.0 star property
Lake City
6.4 out of 10, (268 reviews)
"I loved everything. Room was clean and smelled amazing"
United States
BRIANNA
The price is CA $138
CA $155 total
includes taxes & fees
Nov 10 - Nov 11
Days Inn by Wyndham Lake City
A reception area with a wooden counter, brown leather seating, and a chandelier.

4. Quality Inn Kingstree North

Quality Inn Kingstree North
2.5 star property
Kingstree
6.0 out of 10, (211 reviews)
"The staff was pleasant and helpful, but the amenities were subpar."
United States
Robert
The price is CA $95
CA $106 total
includes taxes & fees
Nov 30 - Dec 1
Quality Inn Kingstree North
A hotel room with a bed, a desk, a chair, a TV mounted on the wall, and a bathroom visible through an open door.

5. Hotel O Deluxe Inn Kingstree Sc Hwy 52

Hotel O Deluxe Inn Kingstree Sc Hwy 52
2.5 star property
Kingstree
2.8 out of 10, (3 reviews)
"No way I would have slept better in my car"
United States
Nick
The price is CA $96
CA $117 total
includes taxes & fees
Nov 10 - Nov 11
Hotel O Deluxe Inn Kingstree Sc Hwy 52
A modern building with a covered parking area, a well-maintained lawn, and a clear sky.

6. Budget Inn Timmonsville

Budget Inn Timmonsville
2.0 star property
Timmonsville
7.0 out of 10, Good, (352 reviews)
"It was good for the price."
United States
Bethany
The price is CA $86
CA $97 total
includes taxes & fees
Nov 9 - Nov 10
Budget Inn Timmonsville
A hotel lobby with a reception desk, seating area, and a television screen.

7. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,392 reviews)
"Comfortable beds and clean environments."
United States
Steven
The price is CA $143
CA $160 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn & Suites Florence Center Area
A spacious room with a large window, a kitchenette, and two chairs.

8. Florence Inn and Suites

Florence Inn and Suites
2.5 star property
Florence
6.8 out of 10, (443 reviews)
"This hotel is horrible"
United States
Latonya
The price is CA $69
CA $78 total
includes taxes & fees
Dec 8 - Dec 9
Florence Inn and Suites
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

9. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (925 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
The price is CA $155
CA $174 total
includes taxes & fees
Nov 9 - Nov 10
TownePlace Suites by Marriott Florence
A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

10. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.4 out of 10, Very good, (425 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is CA $126
CA $141 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn & Suites Florence Civic Center
A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

11. Aloft by Marriott Florence

Aloft by Marriott Florence
3.0 star property
Florence
8.4 out of 10, Very good, (402 reviews)
"Excellent stay"
United States
Darlene
The price is CA $135
CA $159 total
includes taxes & fees
Nov 15 - Nov 16
Aloft by Marriott Florence
A hotel entrance with a stone facade, glass doors, and a number '501' above.

12. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.0 out of 10, Wonderful, (664 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is CA $167
CA $187 total
includes taxes & fees
Nov 12 - Nov 13
Fairfield Inn & Suites by Marriott Florence I-20
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

13. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
The price is CA $161
CA $180 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn & Suites Florence Center
A hotel entrance with a covered walkway, columns, and a number '340' sign.

14. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice and clean hotel"
United States
HANH
The price is CA $161
CA $180 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

15. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay great breakfast clean"
United States
Zachary
The price is CA $172
CA $193 total
includes taxes & fees
Dec 6 - Dec 7
Staybridge Suites Florence - Civic Center by IHG
A hotel lobby with a reception desk, patterned chairs, a dining area, and a kitchen counter.

16. Super 8 by Wyndham Florence SC I-95 North / Hwy 76

Super 8 by Wyndham Florence SC I-95 North / Hwy 76
2.0 star property
Florence
5.2 out of 10, (392 reviews)
"nice place close to hyw.it was ok but for workers staying there way to much noise and partying till 11.00pm every night."
Canada
robert
The price is CA $83
CA $93 total
includes taxes & fees
Nov 9 - Nov 10
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

17. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.2 out of 10, Very good, (1,002 reviews)
"Staff is so helpful hotel is very clean well kept"
United States
Tom
The price is CA $145
CA $171 total
includes taxes & fees
Nov 10 - Nov 11
SpringHill Suites by Marriott Florence
A neatly made bed with a wooden frame, a ceiling fan, and a window with blinds.

18. Bella's Boutique Hotel

Bella's Boutique Hotel
2.0 star property
Hemingway
6.6 out of 10, (21 reviews)
"Great staff & enjoyed our stay- Thank you!!"
United States
Jamie
The price is CA $165
CA $183 total
includes taxes & fees
Nov 9 - Nov 10
Bella's Boutique Hotel
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.

19. Affordable Suites Florence

Affordable Suites Florence
2.5 star property
Florence
9.2 out of 10, Wonderful, (232 reviews)
"Location is awesome and near everything the staff are very friendly and kind will definitely be coming back for more hotel stays"
United States
Cheyenne
The price is CA $97
CA $108 total
includes taxes & fees
Dec 9 - Dec 10
Affordable Suites Florence
A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

20. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.4 out of 10, Good, (1,011 reviews)
"Good rooms for the price"
United States
Louis
The price is CA $93
CA $104 total
includes taxes & fees
Dec 3 - Dec 4
Days Inn by Wyndham Florence Near Civic Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Learn more about Lake City

Stroll through Moore Farms Botanical Garden's lush landscapes, where seasonal blooms and tranquil paths await. Dive into local history at the Bean Market, a restored 1930s tobacco warehouse now hosting community events and showcasing regional culture.

See all hotels in Lake City
A heron standing in a wetland with reflections of trees.

Top reviews in Lake City

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.
The Inn at the Crossroads

The Inn at the Crossroads

The Inn at the Crossroads
Lake City

10/10 Excellent

Super bel hôtel ! Une belle découverte.
Canada
Gael
Reviewed June 27, 2026
The Inn at the Crossroads

Frequently Asked Questions

What's it like to stay at an apartment in Lake City?

You might not have many choices centrally in Lake City, but Expedia can help you locate lodging options in the area with similar amenities to an apartment. When you search on Expedia, you can filter by amenities you might find in an apartment like a kitchen. You can also filter by similar properties such as vacation homes, condos, or guest houses. While in the area, why not enjoy its lakeside and visit its restaurants?

Why would you choose an apartment over a traditional hotel room?

Offering a kitchen for convenient meals, an apartment often has more space than a traditional hotel room. Apartments are a good option for couples who want a more local feel, and also for families wanting the conveniences of home.

What's the best apartment for a stay in Lake City?

Listed below are some of the more popular apartments in the area to choose from: Boutique Private Apt Walk to Downtown Florence: Located 22.3 mi/35.9 km away in Florence. Amenities include free WiFi. Access to onsite laundry facilities is available on site. 717 Modern Space: It's located in Florence, 22.2 mi/35.7 km away.

What can I expect from the weather in Lake City?

Weather is only one factor, but it can really affect your travel plans, especially when you're planning an extended stay in Lake City. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 51°F. Average annual precipitation for Lake City is 53 inches.

What should I see and do in Lake City?

Lake City is known for its restaurants and lakeside. Lions Park and Ronald E. McNair Life History Center are a couple of lovely local spots to get outside and enjoy nature. Other places in town to visit include The Country Club at Lake City and Lynches Lake Historical Society.

What's the best way to get to and around Lake City?

Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into Florence, SC (FLO-Florence Regional), which is located 22.2 mi (35.8 km) from the heart of the city. If you'd like to venture out around the area, you may want to rent a car for your trip.

Explore a world of travel with Expedia