The Alamo, a historic building with a prominent arched entrance and a flagpole in front.

Hotels in Jefferson, San Antonio

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Our top choices for Jefferson hotels

1. San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District, 4.9 km from Jefferson
8.6 out of 10, Excellent, (1,201 reviews)
"Room was clean, very friendly staff"
Canada
Hsiao Tung
The price is CA $121
CA $146 total
includes taxes & fees
Dec 11 - Dec 12
San Antonio Marriott Northwest Medical Center

2. Courtyard by Marriott San Antonio Downtown/Market Square

Courtyard by Marriott San Antonio Downtown/Market Square
3.0 star property
5.9 km from Jefferson
9.2 out of 10, Wonderful, (817 reviews)
"Enjoyed my stay"
United States
Lady
The price is CA $155
CA $185 total
includes taxes & fees
Nov 28 - Nov 29
Courtyard by Marriott San Antonio Downtown/Market Square

3. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District, 6.3 km from Jefferson
8.4 out of 10, Very good, (3,783 reviews)
"Great place to stay"
United States
Gilbert
The price is CA $125
CA $150 total
includes taxes & fees
Nov 15 - Nov 16
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

4. Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District, 8.1 km from Jefferson
9.2 out of 10, Wonderful, (1,535 reviews)
"Nice overnight stay."
United States
Sharon
The price is CA $127
CA $152 total
includes taxes & fees
Nov 15 - Nov 16
Drury Inn & Suites San Antonio Northwest Medical Center

5. AC Hotel by Marriott San Antonio Riverwalk

AC Hotel by Marriott San Antonio Riverwalk
4.0 star property
5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,383 reviews)
"Great location, clean, big rooms"
Mexico
Vinicio
The price is CA $161
CA $192 total
includes taxes & fees
Nov 20 - Nov 21
AC Hotel by Marriott San Antonio Riverwalk

6. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham
2.5 star property
Uptown Central, 8.4 km from Jefferson
9.0 out of 10, Wonderful, (2,398 reviews)
"Great location near the airport."
United States
Elsa
The price is CA $112
CA $133 total
includes taxes & fees
Nov 15 - Nov 16
Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

7. Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 6.1 km from Jefferson
9.4 out of 10, Exceptional, (5,504 reviews)
"Excellent place, great location"
United States
Rafael
The price is CA $181
CA $216 total
includes taxes & fees
Nov 15 - Nov 16
Drury Plaza Hotel San Antonio Riverwalk

8. Comfort Inn and Suites Near Medical Center

Comfort Inn and Suites Near Medical Center
2.5 star property
2.6 km from Jefferson
7.2 out of 10, Good, (2,413 reviews)
"Great hotel for the price, would stay again"
United States
Amy
The price is CA $75
CA $93 total
includes taxes & fees
Dec 8 - Dec 9
Comfort Inn and Suites Near Medical Center

9. Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB
2.5 star property
8.9 km from Jefferson
8.6 out of 10, Excellent, (1,010 reviews)
"Room was clean and staff was very nice."
United States
Justia
The price is CA $96
CA $112 total
includes taxes & fees
Dec 8 - Dec 9
Ramada by Wyndham San Antonio Near SeaWorld/Lackland AFB

10. Best Western Plus Downtown North

Best Western Plus Downtown North
2.5 star property
7.7 km from Jefferson
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay!"
United States
Vanesa
The price is CA $126
CA $147 total
includes taxes & fees
Nov 16 - Nov 17
Best Western Plus Downtown North

11. Wyndham Garden San Antonio Airport

Wyndham Garden San Antonio Airport
3.0 star property
Uptown Central, 8.4 km from Jefferson
8.6 out of 10, Excellent, (2,057 reviews)
"Good place to stay by the airport."
United States
Antonio
The price is CA $115
CA $137 total
includes taxes & fees
Nov 22 - Nov 23
Wyndham Garden San Antonio Airport

12. Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District, 7.1 km from Jefferson
8.8 out of 10, Excellent, (1,003 reviews)
"Great property, nice rooms"
United States
Francisca
The price is CA $126
CA $150 total
includes taxes & fees
Nov 27 - Nov 28
Courtyard by Marriott Medical Center San Antonio

13. La Quinta Inn & Suites by Wyndham San Antonio Downtown

La Quinta Inn & Suites by Wyndham San Antonio Downtown
3.0 star property
Arsenal, 6.1 km from Jefferson
9.0 out of 10, Wonderful, (3,677 reviews)
"Wonderful stay very pleasant..great location easy walking distances for sightseeing. Definitely would book again!"
United States
Glen
The price is CA $125
CA $150 total
includes taxes & fees
Nov 23 - Nov 24
La Quinta Inn & Suites by Wyndham San Antonio Downtown

14. La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB
3.0 star property
9.8 km from Jefferson
9.2 out of 10, Wonderful, (1,172 reviews)
"Great stay for Lackland Air Force Base."
United States
Lakesha
The price is CA $147
CA $172 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham San Antonio Seaworld/LAFB

15. Courtyard by Marriott San Antonio Lackland

Courtyard by Marriott San Antonio Lackland
3.0 star property
8.2 km from Jefferson
8.2 out of 10, Very good, (1,003 reviews)
"Clean room, very roomy, we loved our stay"
United States
Jolynn
The price is CA $117
CA $137 total
includes taxes & fees
Nov 15 - Nov 16
Courtyard by Marriott San Antonio Lackland

16. Element by Marriott San Antonio Riverwalk

Element by Marriott San Antonio Riverwalk
4.0 star property
5.9 km from Jefferson
9.2 out of 10, Wonderful, (1,481 reviews)
"Very good place to stay"
United States
Juan
The price is CA $155
CA $185 total
includes taxes & fees
Nov 29 - Nov 30
Element by Marriott San Antonio Riverwalk

17. Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 13.5 km from Jefferson
9.0 out of 10, Wonderful, (2,073 reviews)
"Excellent vacation location."
United States
Eric
The price is CA $104
CA $183 total
includes taxes & fees
Dec 1 - Dec 2
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

18. Crockett Hotel

Crockett Hotel
3.0 star property
Downtown San Antonio, 6.5 km from Jefferson
8.8 out of 10, Excellent, (2,854 reviews)
"Excellent experience at Crockett Hotel! Comfortable accommodation, friendly staff, and outstanding hospitality. I truly enjoyed my stay and highly recommend it!"
Australia
Zekariyas
The price is CA $108
CA $129 total
includes taxes & fees
Nov 15 - Nov 16
Crockett Hotel

19. Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 6.2 km from Jefferson
9.0 out of 10, Wonderful, (2,394 reviews)
"Perfect location, excellent breakfast and beautifully decorated"
United States
Michael
The price is CA $109
CA $127 total
includes taxes & fees
Nov 23 - Nov 24
Hotel Gibbs Downtown Riverwalk

20. Candlewood Suites San Antonio Lackland AFB Area by IHG

Candlewood Suites San Antonio Lackland AFB Area by IHG
2.5 star property
9.9 km from Jefferson
9.2 out of 10, Wonderful, (976 reviews)
"Staff was great during the stay"
United States
Brandon
The price is CA $164
CA $192 total
includes taxes & fees
Nov 28 - Nov 29
Candlewood Suites San Antonio Lackland AFB Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Jefferson

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A reception area with a modern design, featuring a reception desk, a digital screen, and a view of an old building through a stone archway.
La Quinta Inn & Suites by Wyndham San Antonio Downtown
3.0 star property
9.0
Wonderful
3,677 reviews
View
A modern hotel with a stone facade, a reflective water feature, and a bridge connecting different sections.
Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
9.4
Exceptional
5,504 reviews
View
A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.
Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
9.2
Wonderful
1,535 reviews
View
A circular stone fire pit with two wooden benches, surrounded by a stone patio and string lights.
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
9.0
Wonderful
2,073 reviews
View
A modern outdoor lounge area with a sofa, chairs, and tables.
AC Hotel by Marriott San Antonio Riverwalk
4.0 star property
9.2
Wonderful
1,383 reviews
View

Where to stay in Jefferson

Find the best Jefferson areas and neighborhoods for the activities you enjoy most.

Downtown San Antonio

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Uptown Central

While visiting Uptown Central, you might make a stop by sights like Marion Koogler McNay Art Museum and Alamo Quarry Market.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side

While visiting Northwest Side, you might make a stop by sights like Huebner Oaks and Crystal Ice Palace.

Top Jefferson Hotel Reviews

Frequently asked questions

What are the best hotels in Jefferson that travellers recommend?
For highly recommended hotels in Jefferson, consider O'Casey's Boutique Inn.

The 3-star O'Casey's Boutique Inn, with a 9.0 rating, is frequently praised by guests for its quiet location in a historical district and its charming rooms. This historic-style property offers free continental breakfast and features amenities such as air conditioning and deep soaking bathtubs, providing a comfortable and relaxing stay.
What are the best family hotels in Jefferson?
For family-friendly accommodation in Jefferson, Texas, consider the Comfort Inn and Suites Near Medical Center or the Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG.

The Comfort Inn and Suites Near Medical Center, with a 7.2 rating, provides a pool, connecting rooms, and a sofa bed, alongside a complimentary buffet breakfast. Guests frequently mention the friendly and helpful staff, comfortable and clean rooms, and great value. It is conveniently located near the Wonderland of the Americas Mall, just 1.6 km away.

Another excellent option is the Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG, rated 7.4. This hotel offers a sofa bed, connecting rooms, and complimentary rollaway extra beds, making it ideal for families. A free buffet breakfast and free self-parking are also provided. Guests often highlight the helpful staff, great breakfast, and spacious rooms. It is also close to the Wonderland of the Americas Mall, approximately 1.8 km away.
What hotels in Jefferson offer free breakfast?
Several hotels in Jefferson provide complimentary breakfast for their guests, including O'Casey's Boutique Inn, Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG, and Comfort Inn and Suites Near Medical Center.

The 3-star O'Casey's Boutique Inn, with an excellent 9.0 rating, offers both free breakfast and continental breakfast. Guests frequently mention its quiet location and charming rooms. It is conveniently situated near San Pedro Springs Park, just 0.7 km away.

The Holiday Inn Express & Suites San Antonio NW - Medical Area by IHG, rated 7.4, provides a free buffet breakfast. Guests appreciate the friendly and helpful staff, as well as the spacious rooms. It is located 1.8 km from Wonderland of the Americas Mall.

The Comfort Inn and Suites Near Medical Center, with a 7.2 rating, also features a complimentary buffet breakfast. Visitors often praise the comfortable and clean rooms, as well as the great breakfast options. This hotel is 1.6 km from Wonderland of the Americas Mall.

Other options include Days Inn by Wyndham Central San Antonio NW Medical Center, which offers a free to-go breakfast and has a 7.0 rating, and the 3-star La Quinta Inn By Wyndham IH-10 West San Antonio TX, which provides free breakfast and continental breakfast.
What are the best budget hotels in Jefferson?
For budget-friendly accommodation in Jefferson, O'Casey's Boutique Inn and La Quinta Inn By Wyndham IH-10 West San Antonio TX are both highly regarded options.

The 3-star O'Casey's Boutique Inn, with an excellent rating of 9.0, is praised by guests for its quiet location and charming rooms. It offers complimentary self-parking, free WiFi, and a lovely continental breakfast. Its proximity to San Pedro Springs Park, just 0.7 km away, is a definite advantage for those who enjoy green spaces.

Another excellent choice is the 3-star La Quinta Inn By Wyndham IH-10 West San Antonio TX. Guests consistently mention the excellent and clean rooms, and its convenient location. This hotel also provides complimentary self-parking, free WiFi, and a continental breakfast. It is located 1.9 km from the Wonderland of the Americas Mall, offering easy access to shopping and dining.
What are the most romantic hotels in Jefferson for couples?
For a romantic stay in Jefferson, Texas, O'Casey's Boutique Inn is an excellent choice for couples.

This 3-star boutique inn, with an impressive 9.0 rating, is frequently praised by guests for its quiet location and charming rooms. Couples particularly appreciate the complimentary breakfast, which includes a continental option, and the free toiletries. Free self-parking and free WiFi add to the convenience. Its proximity to San Pedro Springs Park, just 0.7 km away, offers a lovely spot for a romantic stroll.
What are the best hotels in Jefferson near Wonderland of the Americas Mall?
For hotels near Wonderland of the Americas Mall, consider the OYO Inn & Suites Medical Center San Antonio or the Days Inn by Wyndham Central San Antonio NW Medical Center.

The OYO Inn & Suites Medical Center San Antonio, with a 7.2 rating, is a convenient option as it is located just 0.5 kilometres from the Wonderland of the Americas Mall. It offers complimentary self-parking and free toiletries.

Another good choice is the Days Inn by Wyndham Central San Antonio NW Medical Center, rated 7.0. This hotel is located 1.7 kilometres from the mall and provides free breakfast, including a to-go option, and free WiFi. Guests often mention the comfortable beds and rooms.
When is the best time to go to Jefferson?
The best time to visit Jefferson is during the spring (March to May) and autumn (September to November) months.

These seasons offer pleasant weather, with mild temperatures that are ideal for exploring the town's historic sites and enjoying outdoor activities. Spring brings blooming dogwoods and azaleas, making for picturesque strolls through the historic district. Autumn provides comfortable conditions for ghost tours and riverboat excursions, often with colourful foliage adding to the scenery.

For those interested in specific events, autumn is particularly popular due to the various festivals and themed events that take place, such as the Jefferson Pilgrimage, which showcases historic homes. Couples looking for a romantic getaway will appreciate the comfortable weather for horse-drawn carriage rides and candlelit dinners. Families will also find these times enjoyable for exploring museums and taking a ride on the historic railway without the discomfort of summer heat.

While summer (June to August) can be hot and humid, and winter (December to February) can be chilly, these shoulder seasons still offer a good experience, often with fewer crowds.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Jefferson hotel for you.
How much is the nightly rate at a Jefferson hotel?
Hotel prices in Jefferson often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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