Title: Top Hotels in Perry County | Expedia.ca [Vacation Rentals in Perry County](https://expedia.ca/Destinations-In-Perry-County.d553248635976433261.Vacation-Rental-Destinations)[Perry County Car Rentals](https://expedia.ca/Destinations-In-Perry-County.d553248635976433261.Car-Rental-Destinations)[Perry County Vacations](https://expedia.ca/Perry-County.d553248635976433261.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Perry County Hotels ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Perry County Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&lodging=APARTMENT) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=PETS) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Perry+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976433261&latLong=37.727513%2C-89.864545&adults=2&startDate=2025-10-11&d1=2025-10-11&endDate=2025-10-13&d2=2025-10-13&amenities=WATER_PARK) ## Check prices for these dates Tonight [Sep 27 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=553248635976433261&startDate=2025-09-27&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 28 - Sep 29](https://www.expedia.ca/Hotel-Search?regionId=553248635976433261&startDate=2025-09-28&endDate=2025-09-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=553248635976433261&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976433261&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels in Perry County ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Room amenity](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/d42a6e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/c6e7fccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG Perryville 9.4/10 Exceptional (511) "Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! " CA $118 CA $136 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible)](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/4e8bbceb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville Perryville 8.4/10 Very good (913) " Love the stay and staff was great " CA $101 CA $115 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/12e65c55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/082d2613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 Perryville 6.6/10 (118) "Right town, close to enough. " CA $95 CA $109 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/8b8e9c4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville Perryville 6.8/10 (411) "Was a nice place." CA $102 CA $116 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/52e075c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/d1990eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/e5b0b4ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/43000000/42540000/42533900/42533836/46dd8c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Weber Farm - Enjoy a beautiful 100 acre farm! Frohna 10/10 Exceptional (30) "Hosts were great. I just wish they had a second bath or atleast a larger bathroom. " CA $174 CA $275 total includes taxes & fees Oct 23 - Oct 24 [](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h42533836.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/762b23c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/5cf83987.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/0e3da27b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115020000/115013900/115013833/2421ef39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Tub & Creek Views: Secluded Perryville Cabin Perryville 9.6/10 Exceptional (4) "We enjoyed our stay! Peaceful and relaxing.John and Bambi" [](https://www.expedia.ca/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115013833.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/4cc586fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/cc5ded53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/e98b7338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/97000000/96360000/96356100/96356094/b546464d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ste. Genevieve Co. House w/ HOT TUB! Saint Mary 9.8/10 Exceptional (7) "Large space which was great. Big bedrooms. " [](https://www.expedia.ca/St-Mary-Hotels-Ste-Genevieve-Co-House-W-HOT-TUB.h96356094.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/81d05c0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/3fbde3db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/366835ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90678400/90678327/19837905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant Perryville CA $153 CA $282 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Perryville-Hotels-Urban-Loft-1-RED-Urban-Loft-Downtown-Above-BrewCo-Restaurant.h90678327.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/ce2d3d0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/57a0f101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/w1270h1656x10y0-bfc04963.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298151/37a6ca51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TreeLoft at BaseCamp Perryville 10/10 Exceptional (4) "This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. " CA $439 CA $686 total includes taxes & fees Oct 2 - Oct 3 [](https://www.expedia.ca/Perryville-Hotels-TreeLoft-At-BaseCamp.h106298151.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/194b8c0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/0452b7b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/2bec47cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115060000/115053400/115053363/def87d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Tub & Creek Views: Secluded Perryville Cabin Perryville [](https://www.expedia.ca/Perryville-Hotels-Hot-Tub-Creek-Views-Secluded-Perryville-Cabin.h115053363.Hotel-Information) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/327c3e44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts Perryville 9.2/10 Wonderful (17) "Great place to stay! " [](https://www.expedia.ca/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![House (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93201700/93201641/5f56477b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93201700/93201641/b48697bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (0 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93210000/93201700/93201641/af2961db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/94000000/93210000/93201700/93201641/e5c7bd04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'the Brewer Guesthouse' Tiny Home w/ Patio & Yard! Perryville 10/10 Exceptional (2) "The house and host were just awesome, enjoyed our stay Toni even helped me Extend!! Would def stay again:)" [](https://www.expedia.ca/Perryville-Hotels-The-Brewer-Guesthouse-Tiny-Home-W-Patio-Yard.h93201641.Hotel-Information) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/2b8b48eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/500f8d12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/33d3e5f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (Multiple Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98556800/98556793/624f311c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Missouri Castle w/ Private Lake, Pool & 100 Acres! St Mary [](https://www.expedia.ca/St-Mary-Hotels-Missouri-Castle-W-Private-Lake.h98556793.Hotel-Information) ![Outdoor spa tub](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/a2384f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/3260afad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace, books](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/fd7a9adc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106300000/106298200/106298154/w1258h1656x22y0-7ed905af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New! Luxury Meets Nature - TreeRise at BaseCamp Perryville 10/10 Exceptional (1) "Our visit was short but so special. Waylon and Kaci have created a sweet haven of rest in the woods of Missouri. We so appreciated the chance to unplug for a bit. Can’t recommend enough! " CA $397 CA $637 total includes taxes & fees Sep 29 - Sep 30 [](https://www.expedia.ca/Perryville-Hotels-New-Luxury-Meets-Nature-TreeRise-At-BaseCamp.h106298154.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/102000000/101840000/101833500/101833424/00058bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/102000000/101840000/101833500/101833424/cd636b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101840000/101833500/101833424/d443cb1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101840000/101833500/101833424/c2167623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Entire Private Home in Perryville, MO Perryville 10/10 Exceptional (2) "Clean and comfortable it was everything we needed. The property manager was very pleasant to talk to. I would recommend others to stay here." [](https://www.expedia.ca/Perryville-Hotels-Entire-Private-Home-In-Perryville.h101833424.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/92000000/91340000/91332400/91332338/8c87eb9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/92000000/91340000/91332400/91332338/9a57fd42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91340000/91332400/91332338/71dbef1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books](https://images.trvl-media.com/lodging/92000000/91340000/91332400/91332338/c83eb3e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 'The Brewer Guesthouse' Tiny Home w/ Patio & Yard! Perryville 10/10 Exceptional (9) "Clean, quiet, and conveniently located near Perryville. I would definitely stay again." [](https://www.expedia.ca/Perryville-Hotels-The-Brewer-Guesthouse-Tiny-Home-W-Patio-Yard.h91332338.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/84000000/83530000/83520600/83520589/1f486110.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83530000/83520600/83520589/67ee5765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/84000000/83530000/83520600/83520589/996a95e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83530000/83520600/83520589/09016c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic House in heart of Altenburg Altenburg [](https://www.expedia.ca/Altenburg-Hotels-Historic-House-In-Heart-Of-Altenburg.h83520589.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/110000000/109890000/109880200/109880174/d2ff4b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/110000000/109890000/109880200/109880174/c47cd513.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/110000000/109890000/109880200/109880174/c35c5f6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/110000000/109890000/109880200/109880174/w1261h853x9y0-7166b1e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Urban Loft above Restaurants Perryville [](https://www.expedia.ca/Perryville-Hotels-Downtown-Urban-Loft-Above-Restaurants.h109880174.Hotel-Information) ![1 bedroom, desk, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/91000000/90680000/90674600/90674562/8f71408c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90680000/90674600/90674562/9e71f6b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90674600/90674562/56b5cbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90680000/90674600/90674562/7b3a56fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtown Loft w/ Amazing Bath Tub & Shower Perryville 10/10 Exceptional (6) "Amazing place. " CA $153 CA $282 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/Perryville-Hotels-Downtown-Loft-W-Amazing-Bath-Tub-Shower.h90674562.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1018) "Was a clean room, nice staff, good parking " CA $125 CA $133 total includes taxes & fees Oct 1 - Oct 2 [](https://www.expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-11&endDate=2025-10-12®ionId=553248635976433261&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Perry-County.d553248635976433261.Hotel-Destinations)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Perry-County.d553248635976433261.Hotel-Destinations) ## Top Perry County Hotel Reviews ![Holiday Inn Express & Suites Murphysboro - Carbondale by IHG](//images.trvl-media.com/lodging/64000000/63310000/63308800/63308723/2785ae14_y.jpg) ### Holiday Inn Express & Suites Murphysboro - Carbondale by IHG 10/10 Excellent "Best hotel in the Carbondale area!!" [](https://expedia.ca/Carbondale-Hotels-Holiday-Inn-Express-Suites-Murphysboro-Carbondale.h63308723.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Very, Very nice. Always, first think I look at is landscaping. It foretells that attitude of the hotel. Drury of the Cape was nicely done, well maintained and fresh. Ok, good start. Start check in and Travelocity computer was not up to speed with Drury's. Desk person got manager, sorted it in just a few short minutes, with a smile the whole time, and up to my room. Room was immaculate, well appointed, nicely decorated, and just plain comfortable. Relaxed a few minutes in the comfortable chair and went down for complimentary dinner. No gigantic spread but, way more than I expected and very tasty. Eveything about my stay was over the top for the price I paid. Everyone working there seemed happy and smiling genuinely.Absolutely one of the nicest hotels I've ever stayed in. This company has the right idea on providing service while not trying to rob you at the same time. Thank You!" [](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Staff was friendly, room was clean, good location, good rate." [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "this place is awesome! evening snacks and drinks (a meal really!) and very nice breakfast comfortable bed and beautiful grounds-quite rural, but Dairy Queen across the road. easy and safe seeming parking " [](https://expedia.ca/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "Very clean, sincerely friendly staff and very helpful. Pillows and bed comfy. Great location. " [](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Brand new hotel and it’s not even shown on Google maps. Great condition and service!" [](https://expedia.ca/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](//images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "My husband and I love this hotel. We stay here every single time we are in the area. While it’s a little pricier than a few other options it is definitely worth it for us. The hotel is beautiful and the staff is always very accommodating. Emily and the rest of the staff are so sweet and helpful. We will be back soon and can’t wait! " [](https://expedia.ca/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](//images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 10/10 Excellent "Just as pictured. Excellent facility. " [](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](//images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 10/10 Excellent "It was right off the interstate with lots of restaurant options " [](https://expedia.ca/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Perry County - [Perryville Hotels](https://expedia.ca/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Frohna Hotels](https://expedia.ca/Frohna-Hotels.d553248634983521632.Travel-Guide-Hotels) - [Brazeau Township Hotels](https://expedia.ca/Brazeau-Township-Hotels.d553248635976430617.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near National Shrine of Our Lady of the Miraculous Medal](https://expedia.ca/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Hotels.0-l553248621561876731-0.Travel-Guide-Filter-Hotels) - [Hotels near Perryville Country Club](https://expedia.ca/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Hotels near Missouri's National Veterans Memorial](https://expedia.ca/Missouris-National-Veterans-Memorial-Hotels.0-l620724250067501056-0.Travel-Guide-Filter-Hotels) - [Hotels near Shawnee National Forest](https://expedia.ca/Shawnee-National-Forest-Hotels.0-l553248635944113522-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River](https://expedia.ca/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Southern Illinois University](https://expedia.ca/Southern-Illinois-University-Hotels.0-l6091413-0.Travel-Guide-Filter-Hotels) - [Hotels near Mark Twain National Forest](https://expedia.ca/Mark-Twain-National-Forest-Hotels.0-l553248635976468503-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Perry County - [Vacation Homes in Perry County](https://expedia.ca/Perry-County-Private-Vacation-Homes.d553248635976433261-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Perry County](https://expedia.ca/Perry-County-Cabins.d553248635976433261-aaCabins.Travel-Guide-Accommodation) - [Apartments in Perry County](https://expedia.ca/Perry-County-Apartments.d553248635976433261-aaApartments.Travel-Guide-Accommodation) - [Cottages in Perry County](https://expedia.ca/Perry-County-Cottages.d553248635976433261-aaCottages.Travel-Guide-Accommodation) - [Motels in Perry County](https://expedia.ca/Perry-County-Motels.d553248635976433261-aaMotels.Travel-Guide-Accommodation) - [Farmstay in Perry County](https://expedia.ca/Perry-County-Agritourism.d553248635976433261-aaAgritourism.Travel-Guide-Accommodation) - [B&B in Perry County](https://expedia.ca/Perry-County-Bed-And-Breakfast.d553248635976433261-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Lodges in Perry County](https://expedia.ca/Perry-County-Lodges.d553248635976433261-aaLodges.Travel-Guide-Accommodation) - [RV Parks in Perry County](https://expedia.ca/Perry-County-RV-Parks.d553248635976433261-aaRVParks.Travel-Guide-Accommodation) - [Guest Houses in Perry County](https://expedia.ca/Perry-County-Guest-Houses.d553248635976433261-aaGuestHouses.Travel-Guide-Accommodation) - [Aparthotels in Perry County](https://expedia.ca/Perry-County-Apart-Hotels.d553248635976433261-aaApartHotels.Travel-Guide-Accommodation) - [Condo Rentals in Perry County](https://expedia.ca/Perry-County-Condos.d553248635976433261-aaCondos.Travel-Guide-Accommodation) ### Explore more hotels - [Holiday Inn Express & Suites Perryville by IHG](https://expedia.ca/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) - [Super 8 by Wyndham Perryville](https://expedia.ca/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) - [Drury Plaza Hotel Cape Girardeau Conference Center](https://expedia.ca/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) - [The Riverview](https://expedia.ca/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) - [La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://expedia.ca/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) - [Pear Tree Inn Cape Girardeau Near the Medical Center](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) - [University Inn of Carbondale](https://expedia.ca/Carbondale-Hotels-University-Inn-And-Suites.h59964501.Hotel-Information) - [Pear Tree Inn Cape Girardeau West](https://expedia.ca/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) - [Baymont by Wyndham Chester IL](https://expedia.ca/Chester-Hotels-Baymont-By-Wyndham-Chester-IL.h1699.Hotel-Information) - [Super 8 by Wyndham Carbondale](https://expedia.ca/Carbondale-Hotels-Super-8-By-Wyndham-Carbondale.h439693.Hotel-Information) [See a list of all hotels in Perry County](https://expedia.ca/All-Perry-County-Hotels.d553248635976433261.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Perry County on Expedia.com](https://www.expedia.com/Destinations-In-Perry-County.d553248635976433261.Hotel-Destinations) ### Expedia's Latest Trends Hotels - 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