Title: Hotels by Red Roof Inn in Depew from CA $87 | Expedia.ca [Depew Travel Guide](https://expedia.ca/Depew.dx6338362)[Hotels in Depew](https://expedia.ca/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Vacation Rentals in Depew](https://expedia.ca/Depew-Vacation-Rentals.d6338362.Travel-Guide-VacationRentals)[Flights to Depew](https://expedia.ca/Cheap-Flights-To-Depew.d6338362.Travel-Guide-Flights)[Things to do in Depew](https://expedia.ca/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities)[Depew Car Rentals](https://expedia.ca/Car-Rentals-In-Depew.d6338362.Car-Rental-Guide)[Depew Vacation Packages](https://expedia.ca/Depew.d6338362.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 2 - Mar 3](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 3 - Mar 4](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Depew Red Roof Inn ![Deluxe Room, 2 Double Beds (Smoke Free)](https://images.trvl-media.com/lodging/1000000/10000/900/816/dec8cb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/760d0b9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/816/b68133b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/900/816/6d5f06be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.ca/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1,000 reviews) "Room was very clean, staff very courteous " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sonia CA $76 CA $87 total includes taxes & fees Apr 1 - Apr 2 [](https://www.expedia.ca/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Superior Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/10900/10830/b443bdcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10900/10830/a21e30f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10900/10830/cf373e65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/20000/10900/10830/d62bdce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Niagara Falls [](https://www.expedia.ca/Niagara-Falls-Hotels-Red-Roof-Inn-Niagara-Falls.h10830.Hotel-Information) La Salle 5.6/10 (1,003 reviews) "Rooms were very accommodating, clean, and the staff was terrific. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Suetania [](https://www.expedia.ca/Niagara-Falls-Hotels-Red-Roof-Inn-Niagara-Falls.h10830.Hotel-Information) ![In-room safe, desk, blackout drapes, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/24b9dd25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/8659347d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/a8136605.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/1000000/20000/17500/17404/056e4b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo – Hamburg/ I-90 [](https://www.expedia.ca/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Hamburg-I-90.h17404.Hotel-Information) Hamburg 5.8/10 (1,005 reviews) "Staff was great they took care of my needs, " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john [](https://www.expedia.ca/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Hamburg-I-90.h17404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17®ionId=6338362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Red-Roof-Inn.0-0-d6338362--bRedRoofInn.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels-Red-Roof-Inn.0-0-d6338362--bRedRoofInn.Travel-Guide-Filter-Hotels) ## Top Depew Hotel Reviews ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 10/10 Excellent "The manager at the front desk when we checked in was so lovely and helpful and was a delight to talk too. All the staff have great customer service and always have a smile on their face. " [](https://expedia.ca/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ![Holiday Inn Express Cheektowaga North East by IHG](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69_y.jpg) ### Holiday Inn Express Cheektowaga North East by IHG 10/10 Excellent "It was great" [](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information) ![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62_y.jpg) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG 10/10 Excellent "Great place! I will be back" [](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ![Hyatt Place Buffalo/Amherst](https://images.trvl-media.com/lodging/10000000/9460000/9456500/9456445/523e54f1_y.jpg) ### Hyatt Place Buffalo/Amherst 10/10 Excellent "Staff was inviting and kind. Everything very clean." [](https://expedia.ca/Buffalo-Hotels-Hyatt-Place-BuffaloAmherst.h9456445.Hotel-Information) ![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/1edd14d0_y.jpg) ### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG 10/10 Excellent "The rooms were very clean and the staff were on top of things, I will definitely come back " [](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) ![La Quinta Inn by Wyndham Buffalo Airport](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/4969c4dc_y.jpg) ### La Quinta Inn by Wyndham Buffalo Airport 10/10 Excellent "courteous staff, clean room, excellent stay for the price. I woulld stay here again. Thank you!" [](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Buffalo Amherst](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/456d3072_y.jpg) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst 10/10 Excellent "Room clean. Coffee hot and available. " [](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/50c6a12d_y.jpg) ### Holiday Inn Express Grand Island - Niagara Falls by IHG 10/10 Excellent "Room was spotless. Staff were all amazing. Nice quiet place to stay. We will be back." [](https://expedia.ca/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 10/10 Excellent "Wonderful staff! Wonderful room!! Beautiful hotel! Will come again. Affordable too." 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