Title: Depew Guest Houses from CA $247 | Expedia.ca

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## Check prices for these dates

Next weekend

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In one month

[May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6338362&startDate=2026-05-29&endDate=2026-05-31&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Depew guest houses

![Exterior](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/debc1f3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/7b15265b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mini-fridge](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/ec4765b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/116000000/115340000/115334800/115334773/c8096ad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Buffalo Guesthouse

[](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information)

Downtown Buffalo

9.0/10

Wonderful

(130 reviews)

"Great staff, and the accommodations were very pleasant. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tiffany

CA $216

CA $247 total

includes taxes & fees

May 4 - May 5

[](https://www.expedia.ca/Buffalo-Hotels-Buffalo-Guesthouse.h115334773.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/efe76f18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury House, 4 Bedrooms, Patio, City View | Living room](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/7570e194.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Luxury House, 4 Bedrooms, Patio, City View | Private kitchen](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/e698becb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/111000000/110140000/110138900/110138870/d338cda0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Summer Street Guest House

[](https://www.expedia.ca/Buffalo-Hotels-Summer-Street-Guest-House.h110138870.Hotel-Information)

Bryant

10/10

Exceptional

(2 reviews)

"Charles greeted us upon arrival and took us on a tour of his beautiful house. It was magnificent. Spacious and well-appointed. A terrific stay!"

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Anthony

CA $500

CA $733 total

includes taxes & fees

Apr 5 - Apr 6

[](https://www.expedia.ca/Buffalo-Hotels-Summer-Street-Guest-House.h110138870.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top Depew Hotel Reviews

![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/f9a47442_y.jpg)

### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"Very well placed hotel for the theatre district in Buffalo as well as a few train stops down from where the Sabers play hockey. Great hotel and an awesome price!!"

[](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information)

![La Quinta Inn & Suites by Wyndham Buffalo Amherst](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/6499bfe4_y.jpg)

### La Quinta Inn & Suites by Wyndham Buffalo Amherst

8/10 Good

"Everything is good."

[](https://expedia.ca/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information)

![Wyndham Garden Buffalo Downtown](https://images.trvl-media.com/lodging/1000000/160000/159000/158959/dfd9177e_y.jpg)

### Wyndham Garden Buffalo Downtown

4/10 Poor

"Yes"

[](https://expedia.ca/Buffalo-Hotels-Wyndham-Garden-Buffalo-Downtown.h158959.Hotel-Information)

![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349_y.jpg)

### Holiday Inn Express Grand Island - Niagara Falls by IHG

8/10 Good

"Breakfast was great! Very convenient location and quieter than being right by the falls. Room was spacious and clean, great for a family. The pool needs more regular attention as there were no towels both days and lots of stuff floating around in it (hair clumps, bandaids). We loved the rooftop bar! Would come back."

[](https://expedia.ca/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information)

![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg)

### M Hotel Buffalo

2/10 Terrible

"They dont like to give you your downpayment back "

[](https://expedia.ca/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information)

![Holiday Inn Express Cheektowaga North East by IHG](https://images.trvl-media.com/lodging/9000000/8140000/8130600/8130557/d64d0a69_y.jpg)

### Holiday Inn Express Cheektowaga North East by IHG

6/10 Okay

"The woman taking care of the free breakfast was amazing and helpful…. Does a great job… best aspect of our stay!!"

[](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Cheektowaga-North-East.h8130557.Hotel-Information)

![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3_y.jpg)

### Sleep Inn & Suites Buffalo Airport

4/10 Poor

"The hotel could have been cleaner"

[](https://expedia.ca/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information)

![Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f_y.jpg)

### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

10/10 Excellent

"muy buen servicio. "

[](https://expedia.ca/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information)

![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg)

### Garden Place Hotel

10/10 Excellent

"Do a better breakfast like the other hotel "

[](https://expedia.ca/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information)

## Find out more about Depew

## Depew Guest Houses information

| Number of reviews | 132            |
| ----------------- | -------------- |
| Accommodation     | 4 Guest Houses |
| Lowest Price      | CA $247        |
| Highest Price     | CA $733        |

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