A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

4 Stars Hotels in St. Charles, St. Louis from CA $172

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles 4 Star Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for St. Charles 4-star hotels

A buffet with fruits, pastries, and beverages.
A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.
A modern living room with a flat-screen TV, comfortable seating, and decorative items on shelves.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Arnetta
CA $177
CA $207 total
includes taxes & fees
Sep 7 - Sep 8
Renaissance St. Louis Airport Hotel
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A park with a pathway, trees, and a modern sculpture.
A rooftop lounge with large windows, red seating, and a view of the cityscape.
A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
TRACY
CA $186
CA $219 total
includes taxes & fees
Sep 4 - Sep 5
Hyatt Regency St. Louis at The Arch
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
A modern living room with a sofa, coffee table, and bookshelves.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.
A modern bar area with a central fire feature, bar stools, and seating.

3. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Royce
CA $221
CA $263 total
includes taxes & fees
Sep 2 - Sep 3
Live by Loews - St.Louis
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.
A grand hall with rows of chairs arranged for an event, a central floral arrangement, and a large chandelier.

4. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Scott
CA $211
CA $250 total
includes taxes & fees
Sep 7 - Sep 8
Marriott St. Louis Grand
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a large sign indicating it is a hotel.

5. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Tony
CA $146
CA $172 total
includes taxes & fees
Sep 3 - Sep 4
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.
A modern lobby with a large glass sphere, seating areas, and a reception desk.

6. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
CA $200
CA $241 total
includes taxes & fees
Sep 27 - Sep 28
21C Museum Hotel St Louis
A rooftop restaurant with round tables, chairs, and a view of the city.
A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.
A modern lobby with a staircase, seating area, and an exit sign.
A hotel with a prominent sign reading "MOONRISE."

7. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Nicole
CA $191
CA $227 total
includes taxes & fees
Sep 10 - Sep 11
Moonrise Hotel
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.

8. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Lyn
CA $219
CA $299 total
includes taxes & fees
Sep 7 - Sep 8
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A spacious hotel lobby with a central seating area, multiple armchairs, and a bar.
A casino with multiple gaming tables and slot machines.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.

9. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
Ashley
CA $150
CA $194 total
includes taxes & fees
Sep 29 - Sep 30
River City Casino & Hotel
A brick building with a tower, large windows, and a fountain in the garden.
A grand lobby with a chandelier, a staircase, and a central table with a floral arrangement.
A pool area with lounge chairs and umbrellas, a clear blue pool, and a building with a dome in the background.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.

10. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Michael and Julie
CA $203
CA $237 total
includes taxes & fees
Sep 13 - Sep 14
Hilton St. Louis Frontenac
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern restaurant interior with high tables, chairs, and a central bar area.
A lobby with wooden paneling, a green wall, and two armchairs.
A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.

11. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Debra
CA $188
CA $220 total
includes taxes & fees
Sep 27 - Sep 28
The Westin St. Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.
A bakery display case with various pastries and cakes.

12. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Tracey
CA $221
CA $282 total
includes taxes & fees
Sep 7 - Sep 8
Ameristar Casino Resort and Spa
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
A modern building with a unique, curved roof structure.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.

13. The Cheshire

The Cheshire
Richmond Heights
United States
James
CA $224
CA $267 total
includes taxes & fees
Sep 14 - Sep 15
The Cheshire
A modern lounge with a central fire feature, comfortable seating, and large windows offering a city view.
A rooftop bar with a glass railing, yellow bar stools, and a large umbrella.
A rooftop terrace with a glass table, cushioned seating, and a view of the cityscape.
A modern bar area with high tables and stools, large windows with city views, and green chandeliers.

14. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
christopher
CA $226
CA $269 total
includes taxes & fees
Sep 7 - Sep 8
Hilton St. Louis at the Ballpark
A bar area with a central bar, multiple stools, and a chandelier.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.
A grand lobby with a bar area, chandeliers, and seating.
A grand lobby with a large chandelier, a bar area, and classical architecture.

15. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Gregory
CA $175
CA $208 total
includes taxes & fees
Sep 13 - Sep 14
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A restaurant with tables and chairs, large windows, and a view of the street.
A spacious lobby with a high arched ceiling, multiple seating areas, and a central decorative column.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.

16. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Lauren
CA $203
CA $241 total
includes taxes & fees
Sep 20 - Sep 21
St. Louis Union Station Hotel, Curio Collection by Hilton
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.
A hotel room with a sofa, a blue armchair, a desk with a computer, a TV, and a bed.
A modern living room with a flat-screen TV, a sofa, a coffee table, and a kitchen area with a refrigerator and cabinets.
A spacious lobby with leather sofas, a patterned rug, and a reception desk.

17. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
Central West End
United States
Kevin
CA $216
CA $255 total
includes taxes & fees
Sep 6 - Sep 7
DoubleTree by Hilton St. Louis Forest Park
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A cozy living room with a large TV, a fireplace, a Christmas tree, and a view of the city.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.
An outdoor seating area with modern furniture, a metal railing, and a view of surrounding buildings.

18. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Sara
CA $212
CA $249 total
includes taxes & fees
Sep 6 - Sep 7
Le Méridien St. Louis Clayton
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A hotel room with a large bed, a desk with a chair, a television, and a wardrobe.

19. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Eric
CA $188
CA $224 total
includes taxes & fees
Sep 13 - Sep 14
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A bar area with a long counter, multiple stools, and a television mounted on the wall.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.
A buffet area with various food items and a self-service station.

20. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United States
Matthew
CA $169
CA $201 total
includes taxes & fees
Sep 7 - Sep 8
Embassy Suites by Hilton St. Louis Downtown
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
CA $520
CA $608 total
Sep 7 - Sep 8
includes taxes & fees
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
CA $763
CA $891 total
Sep 20 - Sep 21
includes taxes & fees
9.2/10 Wonderful! (583 reviews)
The Ritz-Carlton, St. Louis
Still don't see what you're looking for?
See all properties in St. Charles.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles
A bridge over a calm river with a sunset sky.

Top St. Charles Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

8/10 Good
"Other than the $75 a night incidental charge and $50 a night parking fee its a good hotel"
William 2-night trip
Posted 2 hours ago
Hyatt Regency St. Louis at The Arch
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"I was quite grateful for the embracing hospitality given by the staff. I found it to be exceptional service overall"
Chuk 1-night trip
Posted 12 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

8/10 Good
"This place was very convenient considering my flight got in after midnight and it's so close to the airport. I only stayed over night and checked into another hotel in the city for the weekend. The rooms are old and need some updating (popcorn ceilings), but it was fine for a few hours of sleep and a hot shower."
LaVonda 1-night trip
Posted 1 day ago
Renaissance St. Louis Airport Hotel
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"First time staying at this brand. Loved this stay. In town for couple Cardinals games. Great walkable location, part of Ballpark Village, is right across street from ballpark. Super staff. Awesome indoor/outdoor bar/restaurant/lounge, plus a rooftop bar/lounge. Do have happy hr with reasonable drink prices. Hotel is newer, trendy vibe & decor. Hotel is quiet, heard no one in halls or room doors….don’t get the people who walk out their room and let door slam shut behind em. Doors are slow close which is nice. Bathrooms could use more hooks and maybe couple small shelves. Luggage carts are kept locked, need to ask for one. Def stay here again."
Jessica 1-night trip
Posted 1 day ago
Live by Loews - St.Louis

Find out more about St. Charles

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in St. Charles are calling your name. Known for providing first-rate service in amazing locations, each of the St. Charles 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in St. Charles. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in St. Charles, St. Louis, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top St. Charles hotels with 4 Stars provide everything you need to unwind in style.

Frequently asked questions

What are the best 4-star hotels in St. Charles?
If you're seeking luxury comfort and lots of amenities on your St. Charles escape, check in to Ameristar Casino Resort and Spa. This 4-star hotel features spa facilities and a swimming pool. DoubleTree by Hilton St. Louis - Westport also gets rave reviews from Expedia travellers. Concierge services and limousine services are among its conveniences.
How much does it cost to stay in a 4-star hotel in St. Charles?
We can help you quickly find the perfect 4-star hotel for your stay in St. Charles. Use our filter tool to fine-tune your search by things like budget, conveniences and property star rating and get access to unbeatable deals in a few clicks.
  • Search for the lowest price from CA $608
What's the difference between 5-star and 4-star hotels in St. Charles?
Give yourself the luxury treatment during your St. Charles escape by checking in to a 4-star hotel. As well as featuring upmarket accommodations, these retreats are typically filled with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go above and beyond to make your stay an even more lavish and memorable one. 24-hour front desk, on-site spas and gourmet dining are just the start of the superior services and conveniences you'll likely be able to enjoy.

Explore a world of travel with Expedia