The Fox Theatre with ornate architecture and a marquee.

4 Stars Hotels in Grand Center, St. Louis from CA $158

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Check availability on Grand Center 4 Star Hotels

Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Grand Center 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,380 reviews)
"Great stay"
United States
Tracy
The price is CA $175
CA $207 total
includes taxes & fees
Nov 25 - Nov 26
Hyatt Regency St. Louis at The Arch
A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,144 reviews)
"Wonderful Stay!"
United States
A.R.
The price is CA $201
CA $242 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis
A buffet with fruits, pastries, and beverages.

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,186 reviews)
"The stay was good."
United States
Luther
The price is CA $156
CA $182 total
includes taxes & fees
Nov 20 - Nov 21
Renaissance St. Louis Airport Hotel
A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,055 reviews)
"Great location."
United States
Jennifer
The price is CA $208
CA $248 total
includes taxes & fees
Nov 18 - Nov 19
Moonrise Hotel
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,353 reviews)
"Great place to stay."
United States
brandon
The price is CA $195
CA $231 total
includes taxes & fees
Nov 15 - Nov 16
Live by Loews - St.Louis
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,083 reviews)
"Great place"
United States
Samuel
The price is CA $207
CA $266 total
includes taxes & fees
Nov 25 - Nov 26
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,007 reviews)
"The Sonesta is a lovely hotel with a beautiful pool. Our stay was a relaxing getaway and pleasant in every way."
United States
Kristina
The price is CA $188
CA $263 total
includes taxes & fees
Nov 22 - Nov 23
The Royal Sonesta Chase Park Plaza St. Louis
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (797 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
The price is CA $213
CA $251 total
includes taxes & fees
Nov 15 - Nov 16
Le Méridien St. Louis Clayton
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,005 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
The price is CA $184
CA $215 total
includes taxes & fees
Nov 15 - Nov 16
The Westin St. Louis
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

10. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,002 reviews)
"Good food an"
United States
Ravyn
The price is CA $200
CA $240 total
includes taxes & fees
Nov 13 - Nov 14
Marriott St. Louis Airport
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

11. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,830 reviews)
"Great accommodations - highly recommend"
United States
jodi
The price is CA $122
CA $164 total
includes taxes & fees
Nov 10 - Nov 11
River City Casino & Hotel
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,007 reviews)
"Great location, clean, nice bar area, full service Starbucks, very helpful staff!"
United States
Leonor
The price is CA $178
CA $212 total
includes taxes & fees
Nov 22 - Nov 23
Marriott St. Louis Grand
A bar area with a central bar, multiple stools, and a chandelier.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,400 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
The price is CA $133
CA $158 total
includes taxes & fees
Nov 23 - Nov 24
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,013 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is CA $179
CA $213 total
includes taxes & fees
Nov 1 - Nov 2
Drury Plaza Hotel St. Louis Brentwood
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

15. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,002 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is CA $208
CA $247 total
includes taxes & fees
Nov 1 - Nov 2
The Cheshire
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,363 reviews)
"Loved our stay!"
United States
Megan
The price is CA $159
CA $190 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites by Hilton St. Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,169 reviews)
"Always our top pick to stay when in town for travel. Great people, Great vibes and a Great distance from alot of downtown hot spots ☺️"
United States
Skylee
The price is CA $145
CA $171 total
includes taxes & fees
Nov 22 - Nov 23
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,291 reviews)
"Staff was very friendly and helpful. Room was clean and rooftop bar was great!"
United States
kristen
The price is CA $194
CA $231 total
includes taxes & fees
Nov 22 - Nov 23
Hilton St. Louis at the Ballpark
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,007 reviews)
"Beautiful property. We enjoyed the food & the light shows in the Grand Hall. We also enjoyed riding the St. Louis Wheel & visiting the Aquarium. The “Whispering Wall” caught our attention as well."
United States
Donna
The price is CA $217
CA $258 total
includes taxes & fees
Nov 22 - Nov 23
St. Louis Union Station Hotel, Curio Collection by Hilton
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,158 reviews)
"Enjoyed our stay"
United States
Mary
The price is CA $154
CA $180 total
includes taxes & fees
Nov 15 - Nov 16
Hilton Pennywell St. Louis at the Arch
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Grand Center.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
The price is CA $525 per night from Oct 27 to Oct 28
CA $525
CA $614 total
Oct 27 - Oct 28
includes taxes & fees
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Grand Center Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Very nice. I’ll be back. Celebrities and everythin"
Keva 1-night trip
Posted 1 hour ago
Hyatt Regency St. Louis at The Arch

Frequently asked questions

What are the best 4-star hotels in Grand Centre?
Kick back in the comfort and quality of Angad Arts Hotel. This 4-star hotel around Grand Centre is highly recommended by many Expedia customers and features a terrace and Egyptian-cotton sheets. Another sought-after choice in or near this neighbourhood is St. Louis Union Station Hotel, Curio Collection by Hilton. A swimming pool and concierge services are a couple of things that make it popular.
How much does it cost to stay in a 4-star hotel in Grand Centre?
To find a 4-star hotel in Grand Centre that's within your budget, take advantage of Expedia's handy filters. Take a look at the availability during your chosen dates and use our pricing filter to set your maximum rate. You can also sort your results by the most wallet-friendly property first.

  • Search for the lowest price from CA $614

What's the difference between 5-star and 4-star hotels in Grand Centre?
Offering a friendly traveller experience and upscale décor, 4-star hotels are a fantastic option for your Grand Centre break. These types of accommodations generally come with lots of handy amenities that make it easy to unpack and relax — think large beds, bathrobes, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with exclusive perks and amenities. On-site health clubs, premium toiletries and gourmet dining are typically included at these plush properties.

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