4 Stars Hotels in Defiance, Missouri from CA $179

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Our top choices for Defiance 4-star hotels

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,090 reviews)
"Great place"
United States
Samuel
The price is CA $223
CA $284 total
includes taxes & fees
Nov 16 - Nov 17
Ameristar Casino Resort and Spa

2. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,000 reviews)
"Hotel staff were kind and accommodating. Great stay for a great price!"
United States
April
The price is CA $194
CA $225 total
includes taxes & fees
Nov 28 - Nov 29
DoubleTree by Hilton Hotel St. Louis - Chesterfield

3. DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Westport
8.0 out of 10, Very good, (1,000 reviews)
"Great food too."
United States
Martin
The price is CA $181
CA $210 total
includes taxes & fees
Nov 15 - Nov 16
DoubleTree by Hilton St. Louis - Westport

4. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,001 reviews)
"Very pleasant staff. Nice breakfast. Clean rooms."
United States
Karen
The price is CA $183
CA $213 total
includes taxes & fees
Nov 29 - Nov 30
Hilton St. Louis Frontenac

5. The Inn at Elijah McLeans

The Inn at Elijah McLeans
4.0 star property
Washington
9.0 out of 10, Wonderful, (177 reviews)
"Beautiful scenery and very nice clean rooms"
United States
Jonathan
The price is CA $180
CA $205 total
includes taxes & fees
Dec 6 - Dec 7
The Inn at Elijah McLeans

6. 'the Ruebling House': Bright, Modern, & Renovated!

'the Ruebling House': Bright, Modern, & Renovated!
4.0 star property
Defiance
'the Ruebling House': Bright, Modern, & Renovated!

7. Landing Apartments - Eureka

Landing Apartments - Eureka
4.0 star property
Eureka
Landing Apartments - Eureka

Top Defiance Hotel Reviews

Find out more about Defiance

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Defiance are calling your name. Known for providing first-rate service in amazing locations, each of the Defiance 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Defiance. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Defiance, Missouri, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Defiance hotels with 4 Stars provide everything you need to unwind in style.

Frequently Asked Questions

How much does it cost to stay in a 4-star hotel in Defiance?

We can help you quickly find the perfect 4-star hotel for your vacation in Defiance. Use our filter tool to fine-tune your search by things like price, amenities and star rating and get access to fantastic deals in a few clicks.

  • Search for the lowest price from CA $179

What's the difference between 5-star and 4-star hotels in Defiance?

Treat yourself to refined living during your Defiance getaway by staying at a 4-star hotel. As well as featuring upmarket accommodations, these properties are usually packed with amenities like complimentary bathrobes, large beds and plenty more. A 5-star hotel will go the extra mile to make your trip an even more indulgent and special one. 24-hour front desk, luxurious spas and gourmet dining are a few of the exclusive conveniences and services you'll likely have access to.

Does Defiance have any 4-star all-inclusive resorts?

Enjoy a worry-free vacation experience where almost everything is included in the one upfront price by using our "All inclusive" filter. Sticking to your budget is a cinch when your accommodations, food and many activities are already taken care of. Eager for more options? Browse the incredible deals on our standard 4-star resorts in and around Defiance too.

Are there any 4-star casino hotels in Defiance?

To find your ideal getaway in Defiance, use our convenient filter tools to narrow your search. With resort-style amenities and an upmarket level of service, staying in a 4-star casino hotel is a safe bet for a good time.

Explore a world of travel with Expedia