Title: Book The Best Hotels in Defiance, MO for 2025 from CA $98 - Fully Refundable Options - Expedia.ca

  

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Photo by Michael True

# Find hotels in Defiance, MO from CA $98

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## Go beyond your typical stay in Defiance

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=POOL)

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&travelerType=family_friendly)

Hot tub

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=HOT_TUB)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=PETS)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&lodging=APARTMENT)

Condo

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&lodging=CONDO)

Waterpark

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&amenities=WATER_PARK)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&lodging=COTTAGE)

Chalet

[](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2025-10-09&d1=2025-10-09&endDate=2025-10-11&d2=2025-10-11&lodging=CHALET)

## Check prices for these dates

Tonight

[Sep 24 - Sep 25](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-09-24&endDate=2025-09-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Sep 25 - Sep 26](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-09-25&endDate=2025-09-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Compare 827 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

## Our top choices for Defiance hotels

![Ballroom](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Jetted Tub | Jetted tub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/66ab3de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Wildwood Hotel

Wildwood

9.2/10

Wonderful

(1599)

"We enjoyed our stay!"

CA $123

CA $148 total

includes taxes & fees

Sep 30 - Oct 1

[](https://www.expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/79d56802.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/605f47a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/4b6e8a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel St. Louis St. Charles

St. Charles

9.6/10

Exceptional

(1012)

"Its a great place to stay to enjoy the City."

CA $153

CA $177 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/480000/471500/471447/c6adcbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471500/471447/cda87df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/480000/471500/471447/5fb2c34f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/480000/471500/471447/365f1124.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites St. Louis/Chesterfield

Chesterfield

8.8/10

Excellent

(819)

"There are a lot of restaurants and shops near the hotel."

CA $141

CA $164 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-Suites-St-LouisChesterfield.h471447.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/68baaab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/bdc23fef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/86426a62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/63b04865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton St. Louis Frontenac

Frontenac

8.8/10

Excellent

(1008)

"Great stay. "

CA $200

CA $233 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/d7f7c2c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed with Sofa bed](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/0b60b4dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/73821885.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/2857d67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place St. Louis/Chesterfield

Chesterfield

9.6/10

Exceptional

(1012)

"I appreciated the cleanliness of the rooms and the staff's friendliness."

CA $176

CA $205 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Hyatt-Place-St-LouisChesterfield.h6583788.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3300/3258/47e1344b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3300/3258/d69ba748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3300/3258/657a5ebe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/3300/3258/ed46e92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton Hotel St. Louis - Chesterfield

Chesterfield

8.6/10

Excellent

(1005)

"Good hotel for suburban STL stays. Convenient to interstates and airport"

CA $196

CA $227 total

includes taxes & fees

Sep 27 - Sep 28

[](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-Hotel-St-Louis-Chesterfield.h3258.Hotel-Information)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/50000/42200/42154/54d31f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/50000/42200/42154/1057ce09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, pillowtop beds, desk](https://images.trvl-media.com/lodging/1000000/50000/42200/42154/cb77ee79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42154/1ac706c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn St. Louis/Chesterfield

Chesterfield

8.6/10

Excellent

(1006)

"Great staff and atmosphere "

CA $146

CA $170 total

includes taxes & fees

Oct 13 - Oct 14

[](https://www.expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisChesterfield.h42154.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/416a6a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/ec5f72c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/167bb75f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/f8b9cd17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites Southwest St. Louis

Valley Park

9.4/10

Exceptional

(1024)

"Had a great stay, best hotel breakfast we’ve seen and we travel a lot!"

CA $160

CA $187 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/789a4568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily continental breakfast (USD 9.99 per person)](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/58978693.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/5596ba48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/f07353d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn St. Louis - Creve Coeur by IHG

St. Louis

9.0/10

Wonderful

(316)

"Nice place to stay."

CA $154

CA $185 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Creve-Coeur.h38967650.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/cf4e5d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/68bc6d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/0c7d61f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/c663f0eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Inn & Suites St. Louis St. Peters

St. Peters

9.2/10

Wonderful

(1009)

"Very friendly staff and very handy location!"

CA $153

CA $176 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/0c098574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rodeo Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/b33425c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hollywood Casino & Hotel St. Louis

Maryland Heights

8.4/10

Very good

(2163)

"Great stay!"

CA $122

CA $163 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/3c4503ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/w3837h2557x3y4-eb15a187.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/w3837h2561x3y0-eb98b853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/w3837h2557x3y4-9bb734a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel St. Louis Creve Coeur

Creve Coeur

9.2/10

Wonderful

(1015)

"A really nice place for families "

CA $158

CA $184 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Creve-Coeur.h74657.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/cca92dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/a6dd6a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/w2901h1303x0y3-988798bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/74000000/73100000/73099900/73099889/b163097a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel by Marriott St. Louis Chesterfield

Chesterfield

9.2/10

Wonderful

(206)

"Loved my stay here "

CA $217

CA $251 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/St-Louis-Hotels-AC-Hotel-By-Marriott-St-Louis-Chesterfield.h73099889.Hotel-Information)

![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/3e3fd603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/502ee41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 2 Queen Beds](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/918fec62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/422bb82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ameristar Casino Resort and Spa

St. Charles

8.4/10

Very good

(1019)

"Beautiful hotel with friendly staff!"

CA $218

CA $278 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information)

![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/b774ae26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/f06ceba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/6f3a3dcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/c9911b85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Chesterfield

9.0/10

Wonderful

(1000)

"Clean and great rooms"

CA $152

CA $177 total

includes taxes & fees

Oct 5 - Oct 6

[](https://www.expedia.ca/St-Louis-Hotels-SpringHill-Suites-By-Marriott-St-Louis-Chesterfield.h126794.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/1000000/20000/19400/19336/67aabb2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/19400/19336/6291a221.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/19400/19336/222f2949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/19400/19336/436e2a93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton St. Louis - Westport

Maryland Heights

8.2/10

Very good

(1005)

"Great place"

CA $176

CA $204 total

includes taxes & fees

Oct 2 - Oct 3

[](https://www.expedia.ca/St-Louis-Hotels-DoubleTree-By-Hilton-Hotel-St-Louis-Westport.h19336.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/22000000/21320000/21314200/21314174/1cd3a521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/22000000/21320000/21314200/21314174/063d2928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/22000000/21320000/21314200/21314174/5470a6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/22000000/21320000/21314200/21314174/eb725c7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn St. Louis Airport

Bridgeton

8.4/10

Very good

(912)

"Great location to the airport, comfortable stay!"

CA $126

CA $151 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/St-Louis-Hotels-Sleep-Inn-St-Louis-Airport.h21314174.Hotel-Information)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781241/34da99c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781241/w4000h2663x0y0-e598fe4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781241/21f54f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781241/ee238b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SpringHill Suites by Marriott St. Louis Airport/Earth City

Bridgeton

8.8/10

Excellent

(1005)

"love the breakfast. "

CA $145

CA $172 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/St-Louis-Hotels-SpringHill-Suites-By-Marriott-St-Louis-AirportEarth-City.h1781241.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/e5c2fe9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/9583b545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/a58c51fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Drury Plaza Hotel St. Louis Chesterfield

Chesterfield

9.6/10

Exceptional

(1019)

"Great place to stay! "

CA $181

CA $210 total

includes taxes & fees

Sep 29 - Sep 30

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/446bd1a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c85b5876.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

8.2/10

Very good

(1034)

"The staff was nice, breakfast was good, the location was convenient. "

CA $124

CA $143 total

includes taxes & fees

Sep 28 - Sep 29

[](https://www.expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10&regionId=6353634&adults=2&sort=RECOMMENDED&openPlayBack=true)

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Save an average of 15% on thousands of hotels when you're signed in

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## Learn more about Defiance

Trip time! Discover the wineries, parks, and history in Defiance.

[See all hotels in Defiance](https://www.expedia.ca/Hotel-Search?startDate=2025-10-09&endDate=2025-10-10&adults=2&regionId=6353634)

![](https://mediaim.expedia.com/destination/9/db5eb599ca7c4918fd6575109a51c6ac.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

### Stay near popular Defiance attractions

[](https://expedia.ca/Busch-Stadium-Hotels.0-l502872-0.Travel-Guide-Filter-Hotels)

![Busch Stadium](https://mediaim.expedia.com/destination/1/fc7b602fbc184e7e7e6b56e34fb1afe4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art scene or attend a baseball game.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502872)

[](https://expedia.ca/St-Louis-Union-Station-Hotels.0-l502868-0.Travel-Guide-Filter-Hotels)

![St. Louis Union Station](https://mediaim.expedia.com/destination/9/55f06578213cb4d3e5a61c6fa51be851.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Union Station

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's acclaimed theater scene or attend a baseball game.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502868)

[](https://expedia.ca/Gateway-Arch-Hotels.0-l502855-0.Travel-Guide-Filter-Hotels)

![Gateway Arch featuring modern architecture, a city and a skyscraper](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/28000/28954-Gateway-Arch.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502855)

[](https://expedia.ca/St-Louis-Zoo-Hotels.0-l502878-0.Travel-Guide-Filter-Hotels)

![St. Louis Zoo](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/200000/200067-St-Louis-Zoo.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=502878)

[](https://expedia.ca/City-Museum-Hotels.0-l6069375-0.Travel-Guide-Filter-Hotels)

![City Museum showing a city as well as children](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199840-City-Museum.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### City Museum

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6069375)

[](https://expedia.ca/Forest-Park-Hotels.0-l6005687-0.Travel-Guide-Filter-Hotels)

![Forest Park featuring a pond, flowers and a garden](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/199000/199633-Saint-Louis.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Forest Park

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

[See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6005687)

## More cheap stays in Defiance

![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Relax Inn Saint Charles

3800 Harry S Truman Blvd, St. Charles, MO

CA $85

CA $98 total

Sep 28 - Sep 29

includes taxes & fees

6.4/10 (1,003 reviews)

[](https://expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information)

![Sleep Inn & Suites O'Fallon MO - Technology Drive](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/133d5cf7_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sleep Inn & Suites O'Fallon MO - Technology Drive

1147 Technology Drive, O'Fallon, MO

CA $124

CA $146 total

Sep 28 - Sep 29

includes taxes & fees

8.8/10 Excellent! (1,008 reviews)

[](https://expedia.ca/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information)

![Best Western Plus St. Louis West-Westport](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Best Western Plus St. Louis West-Westport

12220 Dorsett Rd, Maryland Heights, MO

CA $123

CA $142 total

Oct 19 - Oct 20

includes taxes & fees

7.8/10 Good! (1,012 reviews)

[](https://expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

![Hampton Inn St. Charles St. Peters](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/8c366380_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn St. Charles St. Peters

3720 W Clay St, St. Charles, MO

CA $124

CA $143 total

Oct 5 - Oct 6

includes taxes & fees

8/10 Very Good! (1,010 reviews)

[](https://expedia.ca/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information)

![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Country Inn & Suites by Radisson, St. Charles Historic District

1190 S Main St, St. Charles, MO

CA $158

CA $182 total

Sep 28 - Sep 29

includes taxes & fees

9.4/10 Exceptional! (1,020 reviews)

[](https://expedia.ca/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![Baymont by Wyndham St. Charles](https://images.trvl-media.com/lodging/1000000/50000/41500/41491/8dfa5f2b_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Baymont by Wyndham St. Charles

801 Veterans Memorial Parkway, St. Charles, MO

[Get rates](https://expedia.ca/Hotel-Search?startDate=09%2F10%2F2025&endDate=10%2F10%2F2025&selected=41491&PinnedHotelID=41491&HadPinnedHotel=true&regionId=6353634)

7.8/10 Good! (1,001 reviews)

[](https://expedia.ca/St-Louis-Hotels-Baymont-By-Wyndham-St-Charles.h41491.Hotel-Information)

## Hotels in Defiance with star-rating

![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/68baaab6_w.jpg)

4 Star Hotels

6 properties

[](https://expedia.ca/4Star-Defiance-Hotels.s40-0-d6353634.Travel-Guide-Filter-Hotels)

![3 Star Hotels](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_w.jpg)

3 Star Hotels

112 properties

[](https://expedia.ca/3Star-Defiance-Hotels.s30-0-d6353634.Travel-Guide-Filter-Hotels)

![2 Star Hotels](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_w.jpg)

2 Star Hotels

134 properties

[](https://expedia.ca/2Star-Defiance-Hotels.s20-0-d6353634.Travel-Guide-Filter-Hotels)

## Recent reviews of Defiance hotels

![Drury Plaza Hotel St. Louis Chesterfield](//images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/c1fcfc39_y.jpg)

### Drury Plaza Hotel St. Louis Chesterfield

5/5 Excellent

"Probably the nicest hotel we've stayed in! Everyone was so nice and accommodating. A treat bag for our pup, free dinner, free drinks, and free breakfast?!? Pool was indoor and outdoor!! Amazing!"

A verified traveller stayed at Drury Plaza Hotel St. Louis Chesterfield

Posted 3 days ago

[](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information)

![Relax Inn Saint Charles ](//images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/3d3bc786_y.jpg)

### Relax Inn Saint Charles

5/5 Excellent

"Good staff"

A verified traveller stayed at Relax Inn Saint Charles

Posted 4 days ago

[](https://expedia.ca/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information)

![Best Western Plus St. Louis West-Westport](//images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25_y.jpg)

### Best Western Plus St. Louis West-Westport

5/5 Excellent

"It was a very nice place"

A verified traveller stayed at Best Western Plus St. Louis West-Westport

Posted 4 days ago

[](https://expedia.ca/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information)

![The Wildwood Hotel](//images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg)

### The Wildwood Hotel

5/5 Excellent

Affordable Elegance

"A great experience Staff is helpful and truly proud of their hotel. A very pleasant stay in classy environment. "

A verified traveller stayed at The Wildwood Hotel

Posted 6 days ago

[](https://expedia.ca/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

![Sonesta ES Suites St. Louis - Chesterfield](//images.trvl-media.com/lodging/1000000/10000/500/422/a42ce99e_y.jpg)

### Sonesta ES Suites St. Louis - Chesterfield

5/5 Excellent

"Best breakfast options"

A verified traveller stayed at Sonesta ES Suites St. Louis - Chesterfield

Posted 6 days ago

[](https://expedia.ca/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information)

![Hollywood Casino & Hotel St. Louis](//images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg)

### Hollywood Casino & Hotel St. Louis

5/5 Excellent

"Great places to jo"

A verified traveller stayed at Hollywood Casino & Hotel St. Louis

Posted 7 days ago

[](https://expedia.ca/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![Holiday Inn St. Louis - Creve Coeur by IHG](//images.trvl-media.com/lodging/39000000/38970000/38967700/38967650/789a4568_y.jpg)

### Holiday Inn St. Louis - Creve Coeur by IHG

5/5 Excellent

"Friendliness and helpfulness of your staff! Room was very clean."

A verified traveller stayed at Holiday Inn St. Louis - Creve Coeur by IHG

Posted 7 days ago

[](https://expedia.ca/St-Louis-Hotels-Holiday-Inn-St-Louis-Creve-Coeur.h38967650.Hotel-Information)

![Courtyard by Marriott St Louis Creve Coeur](//images.trvl-media.com/lodging/1000000/20000/11100/11052/96f17f89_y.jpg)

### Courtyard by Marriott St Louis Creve Coeur

5/5 Excellent

"Very clean, friendly staff. "

A verified traveller stayed at Courtyard by Marriott St Louis Creve Coeur

Posted 7 days ago

[](https://expedia.ca/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Creve-Coeur.h11052.Hotel-Information)

![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](//images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg)

### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

5/5 Excellent

"Very good hotel "

A verified traveller stayed at Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Posted 8 days ago

[](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information)

## Frequently asked questions

### When is the best time to go to Defiance?

> The most popular time to visit Defiance is during the summer months, particularly in July, when the weather is warm and inviting. With average temperatures ranging from 22 to 28°C, it's the superb backdrop for outdoor adventures, whether you're exploring the scenic Maumee River or enjoying local events in the parks.
> 
>   
> 
> During the peak season from July to September, Defiance buzzes with activity. Festivals and community gatherings take place, providing visitors with a delightful opportunity to immerse themselves in the local culture. The vibrant atmosphere makes it ideal for families and couples alike, as there are plenty of outdoor activities, such as hiking, biking, and picnicking, in the surrounding nature.
> 
>   
> 
> If you're looking for a more budget-friendly time to visit, consider late September or early October. While the weather may start to cool slightly, with temperatures around 15 to 20°C, the autumn foliage offers a beautiful setting for sightseeing. This time of year also means fewer crowds, allowing you to enjoy the attractions at a more leisurely pace.

### Can I cancel my hotel reservation on Expedia?

> Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Defiance hotel for you.

### How can I save on a Defiance hotel booking with Expedia?

> Members always get our best prices. Find our best Defiance hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.

### How much is the nightly rate at a Defiance hotel?

> Prices for hotels in Defiance often vary, but you can find a great deal from CA $98 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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-   [Hotels near Six Flags St. Louis](https://www.expedia.ca/Six-Flags-St-Louis-Hotels.0-l6147083-0.Travel-Guide-Filter-Hotels)
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-   [Townhomes in Wildwood](https://www.expedia.ca/Wildwood-Townhomes.d6085106-aaTownhomes.Travel-Guide-Accommodation)

-   [Flights to Gray Summit](https://www.expedia.ca/Cheap-Flights-To-Gray-Summit.d6055922.Travel-Guide-Flights)
-   [Flights to Wildwood](https://www.expedia.ca/Cheap-Flights-To-Wildwood.d6085106.Travel-Guide-Flights)
-   [Flights from Wildwood](https://www.expedia.ca/lp/flights/6085106/flights-from-wildwood)
-   [Flights from Newton (EWK) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/ewk/sus/newton-to-st-louis)
-   [Flights from Niagara Falls (IAG) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/iag/sus/niagara-falls-to-st-louis)
-   [Flights from Little Rock (LIT) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/lit/sus/little-rock-to-st-louis)
-   [Flights from Poplar Bluff (POF) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/pof/sus/poplar-bluff-to-st-louis)
-   [Flights from Vancouver (YVR) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/yvr/sus/vancouver-to-st-louis)
-   [Flights from Toronto (YYZ) to St. Louis (SUS)](https://www.expedia.ca/lp/flights/yyz/sus/toronto-to-st-louis)

-   [Labadie Vacations](https://www.expedia.ca/Labadie.d3000445125.Destination-Travel-Guides)
-   [Six Flags St. Louis](https://www.expedia.ca/Six-Flags-St-Louis-St-Louis.d6147083.Vacation-Attraction)
-   [Wildwood Vacations](https://www.expedia.ca/Wildwood.d6085106.Destination-Travel-Guides)

-   [Rental cars Spirit of St. Louis airport](https://www.expedia.ca/Car-Rentals-In-Spirit-Of-St-Louis.d6024951.Car-Rental-Guide)
-   [Car rentals near St. Louis Premium Outlets](https://www.expedia.ca/Car-Rentals-In-St-Louis-Premium-Outlets.d553248621561876860.Car-Rental-Guide)
-   [Car rental Wildwood](https://www.expedia.ca/Car-Rentals-In-Wildwood.d6085106.Car-Rental-Guide)
-   [National Car Rental Rental Cars in Spirit of St. Louis](https://www.expedia.ca/National-Car-Rental-Car-Rentals-In-Spirit-Of-St-Louis.d6024951-c42.Car-Rental-Guide-Suppliers)
-   [Pickup Car Rentals near Show Me](https://www.expedia.ca/Pickup-Car-Rentals-In-Show-Me.d553248635996618251-tPickup.Car-Rental-Guide-Class)

-   [Book Hotels in Defiance on Expedia.com](https://www.expedia.com/Defiance-Hotels.d6353634.Travel-Guide-Hotels)

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