Defiance Vacation Packages

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Your Defiance Vacation

Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.

Top Defiance Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza St. Louis Airport, an IHG Hotel

Crowne Plaza St. Louis Airport, an IHG Hotel

3.5 out of 5
per person
Jul. 28 - Jul. 31
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
7.8/10 Good! (1,003 reviews)
Overall, my stay was good. The bed was very comfortable. I am not sure I would stay during a holiday again, because of the loud children running through the halls. I know that was not the hotel fault, but that was on the parents.

Reviewed on May 28, 2024

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
Jul. 28 - Jul. 31
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.8/10 Excellent! (1,281 reviews)
The staff was very professional and kind. The hotel was very clean and well upkept.

Reviewed on Jun. 2, 2024

Hilton St. Louis Airport

Hilton St. Louis Airport

3.5 out of 5
Woodson Terrace
per person
Jul. 28 - Jul. 31
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
7.6/10 Good! (1,003 reviews)
Did not care for the parking lot arrangement. The sign said $15 a day inside we were told it was $16

Reviewed on Jun. 5, 2024

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
per person
Jul. 28 - Jul. 31
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.2/10 Very Good! (1,006 reviews)
Our group had the best time.

Reviewed on May 31, 2024

The Cheshire

The Cheshire

4 out of 5
per person
Jul. 28 - Jul. 31
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to St. Louis (STL)
8.4/10 Very Good! (1,004 reviews)
The property was safe, clean and the staff were friendly. The room was a good size and comfortable. Only negatives were in places it seemed a little tired and the beds particularly were a bit of a hazard as they stuck out at the corners and both myself and my partner bashed our shins a couple of times! I also dont believe the pool was open, though it seemed to be the case on the East side of the US that pools dont open until the end of May. The breakfast included the next day was good and had lots of options.

Reviewed on Jun. 2, 2024

Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis
Hollywood Casino & Hotel St. Louis
3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $151 per night from Jun. 9 to Jun. 10
CA $151
CA $189 total
includes taxes & fees
Jun 9 - Jun 10
8/10 Very Good! (1,224 reviews)
"Clean updated"

Reviewed on Jun. 5, 2024

Hollywood Casino & Hotel St. Louis
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
Days Inn and Suites by Wyndham St. Louis/Westport Plaza
2.5 out of 5
1970 Craig Rd, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $88 per night from Jul. 1 to Jul. 2
CA $88
CA $103 total
includes taxes & fees
Jul 1 - Jul 2
4.6/10 (1,012 reviews)
"Good"

Reviewed on May 26, 2024

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
La Quinta Inn & Suites by Wyndham St. Louis Westport
La Quinta Inn & Suites by Wyndham St. Louis Westport
2.5 out of 5
11805 Lackland Rd, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $106 per night from Jun. 23 to Jun. 24
CA $106
CA $123 total
includes taxes & fees
Jun 23 - Jun 24
7.4/10 Good! (1,017 reviews)
"I stayed at this LaQuinta 6 years ago and liked it. I was disappointed this time. The hot tub they used to have got paved over. The first room I was given smelled so strongly of ammonia that I couldn’t use it. The second room smelled like industrial cleaner and gave me a headache. The bathtub had ..."

Reviewed on Jun. 3, 2024

La Quinta Inn & Suites by Wyndham St. Louis Westport
See all 790 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a Defiance vacation package cost?
Get set to book, because a getaway to Defiance starts from an affordable CA $999. When you combine your flights, hotels and more into a package, you’ll score the best prices.
How do I get a cheap travel package to Defiance?
It’s as simple as bundling. Flights, rental cars and hotels — combine whatever you need into a Defiance vacation package to save a pile of cash. Score even bigger bargains when you add extras such as day tours to your booking. But that’s not the only impressive part. You have the freedom to put together your trip your own way. We offer more than 550 air carriers and 1,000,000 hotels throughout the world, so that everyone has an opportunity to travel and fulfill those vacation fantasies.
Where should I stay in Defiance?
With interesting attractions such as Chandler Hill Vineyards and August A. Busch Memorial Conservation Area in this area, see if you can find a hotel near them. Historic Daniel Boone Home and Heritage Center is another Defiance sight that people flock to.
What are the top hotels in Defiance?
Lock in a room at The Ruebling House’ Historic Defiance Apartment. It’s one of this neighborhood’s most in-demand hotels. Another great option in Defiance is The Ruebling House’ Cozy 2nd.
How far in advance should I book my Defiance vacation?
To score cheap prices, book nice and early. Air carriers typically advertise flights, along with some of the lowest fares, nearly a year in advance. Hotels, activities and car rental should also be booked early to avoid disappointment. If you’re in need of a last-minute getaway to Defiance, there are always lots of great deals on Expedia. Book something in today!
What does an Expedia Defiance travel package include?
Hotels, flights and a cool car for all your fun road trip adventures. Simply choose your favorite bundle and gain access to great discounts. Once you’ve made your booking, add on a few sightseeing tours and watch your savings stack up. When it comes to creating your Defiance vacation, you’re in control!
What should I know before booking a Defiance travel package?
You’ll land great savings when you combine your hotels, flights and rental cars into a travel package. Not just that, booking everything in one place just makes things easier. So why waste your time or money? Whether you’re putting together a luxury city stay with your love or an affordable family break, have a look at our package deals today.
Can I choose my airline with a Defiance Expedia vacation package?
Yes, so take your pick! Expedia has access to more than 550 partner airlines all over the world, so you can tailor your Defiance trip according to your budget and travel needs.
If I'm not able to travel, can I cancel my Defiance vacation package?
We totally get it — the universe can throw the odd curveball. If you’ve booked a Defiance vacation package and have to cancel or amend it, we’re here to help. We suggest browsing our Customer Service Portal first for information. But generally speaking, if you’ve booked your package within 24 hours, you may be able to amend or cancel your itinerary free of charge. If it’s been more than 24 hours, your hotel, airline or car rental company may charge a fee.

Discover the most popular places to visit in Defiance

Image for St. Louis Union Station

St. Louis Union Station

4.5/5(7 reviews)

You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

St. Louis Union Station
Image for Busch Stadium

Busch Stadium

5/5(19 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Busch Stadium
Image for St. Louis Zoo

St. Louis Zoo

4.5/5(7 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

What to do in Defiance

Image for The Dinner Detective Murder Mystery Dinner Show - St. Louis, MO

The Dinner Detective Murder Mystery Dinner Show - St. Louis, MO

CA $117
Per adult
The Dinner Detective Murder Mystery Dinner Show - St. Louis, MO
Image for Scavenger Hunt in St. Louis by Crazy Dash

Scavenger Hunt in St. Louis by Crazy Dash

CA $14
Per adult
Scavenger Hunt in St. Louis by Crazy Dash
Image for Scavenger Hunt at Washington U!

Scavenger Hunt at Washington U!

CA $17
Per adult
Scavenger Hunt at Washington U!
See all activities in Defiance
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.