Defiance Vacation Packages

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Your Defiance Vacation

Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.

Top Defiance Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Aloft St. Louis Cortex

Aloft St. Louis Cortex

3 out of 5
Central West End
per person
Nov 3 - Nov 5
found 14 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to St. Louis (STL)
8.6/10 Excellent! (717 reviews)
We loved everything about the property.

Reviewed on Aug. 2, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
Oct 3 - Oct 5
found 21 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,558 reviews)
The bed was horrific. The amount of mildew on the shower head was pretty crazy as well. To take a good shower, you'd have to be about 5 foot 5 inches with how low the shower head hung

Reviewed on Aug. 6, 2025

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG

3 out of 5
per person
Oct 3 - Oct 5
found 21 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,000 reviews)
great hotel clean and staff was fantasic

Reviewed on Aug. 3, 2025

Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO

3 out of 5
per person
Oct 3 - Oct 5
found 21 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (690 reviews)
The food in the restaurant was terrable. I had the meat balls and I could not eat them

Reviewed on Jun. 30, 2025

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
Central West End
per person
Nov 3 - Nov 5
found 14 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to St. Louis (STL)
8.2/10 Very Good! (1,000 reviews)
Close to Barnes, access to wnter hotel had only one area, had to have key cards redone as wouldnt access room or car parking. Good staff, clean room, quiet even tho in busy area.

Reviewed on Jul. 31, 2025

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Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $152 per night from Aug 10 to Aug 11
CA $152
CA $197 total
Aug 10 - Aug 11
includes taxes & fees
8.2/10 Very Good! (2,038 reviews)
"Alright, so the only reason we stayed at this place — and I mean the only — was the location. Right near the concert venue. Walkable. No Uber. No nonsense. Just feet on pavement, baby. So yeah, that part? Solid. No complaints. Now the room itself? Look, it wasn’t disgusting. It just... felt like ..."

Reviewed on Aug. 3, 2025

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Aug 31 to Sep 1
CA $123
CA $142 total
Aug 31 - Sep 1
includes taxes & fees
8.2/10 Very Good! (1,001 reviews)
"Everyone at the front desk was very nice. We had a little accident while opening a bottle of pop and it exploded all over the side of the bed, but getting the change of linens and extra pillows were great. Breakfast was delicious, too! Would definitely stay again!"

Reviewed on Aug. 8, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $102 per night from Sep 8 to Sep 9
CA $102
CA $118 total
Sep 8 - Sep 9
includes taxes & fees
7.2/10 Good! (1,010 reviews)
"Great Service and Rooms are Excellent"

Reviewed on Aug. 7, 2025

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
See all 840 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Defiance

Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch featuring modern architecture, a city and a skyscraper

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

What to do in Defiance

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

CA $31
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

CA $33
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

CA $232
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in Defiance

Frequently asked questions

How much does a Defiance vacation package cost?
You can grab a vacation package to this destination from CA $478 on Expedia. However, how much your vacation to Defiance costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
The off-season is the best time to travel to Defiance if you're hoping to keep costs down. Another tip for getting cheap Defiance vacation packages? Avoid visiting during public holidays and any major festivals.
How many days is enough for Defiance?
The ideal duration for your Defiance vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the major attractions and discover some hidden spots along the way.
How to find the best Defiance package deals?
Begin your search for a Defiance package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Defiance package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Defiance getaway off to a flying start.
Is it cheaper to book a Defiance vacation as a package?
You can enjoy significant savings on your next Defiance retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Defiance?
If you've got your Defiance vacation dates locked in, book as early as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are great for travelling on a whim.
How to plan a trip to Defiance?

  1. Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
  2. Set a budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Defiance. Then, pick a property that works with your budget, whether that's a low-cost stay or a lavish retreat.
  3. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Defiance. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Defiance vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.