Defiance Vacation Packages
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Your Defiance Vacation
Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.
Top Defiance Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Sonesta ES Suites St. Louis - Chesterfield
Price was CA $1,730, price is now CA $1,317 per person
CA $1,317
per person
Mar 20 - Mar 22
found 2 days ago
Roundtrip flight included
Saskatoon (YXE) to St. Louis (STL)
8/10 Very Good! (1,018 reviews)
There are many dogs at the property and unfortunately most people do not pick up the excrement of their animal which is disturbing. The property is not kept clean enough. The rooms have very old furniture and carpeting that needs a refresh. I had them come and reclean the room and it was better.
Reviewed on Jan 2, 2026
DoubleTree by Hilton Hotel St. Louis - Chesterfield
Price was CA $1,897, price is now CA $1,427 per person
CA $1,427
per person
Mar 20 - Mar 22
found 2 days ago
Roundtrip flight included
Saskatoon (YXE) to St. Louis (STL)
8.6/10 Excellent! (1,001 reviews)
Clean rooms, comfortable beds, kind and helpful staff such as Kim, Brandon at the front desk, Michelle our house keeper were all fantastic.
Reviewed on Nov 26, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was CA $2,002, price is now CA $1,529 per person
CA $1,529
per person
Mar 20 - Mar 22
found 2 days ago
Roundtrip flight included
Saskatoon (YXE) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
It was good and beautiful on the inside. Loved all the art. The bed was comfy and the room was like an apartment .The only thing that stunk is that there wasn't a microwave in the room. But there was one on the floor so it worked out.
Reviewed on Feb 3, 2026
Ameristar Casino Resort and Spa
Price was CA $1,993, price is now CA $1,531 per person
CA $1,531
per person
Mar 20 - Mar 22
found 2 days ago
Roundtrip flight included
Saskatoon (YXE) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
The room was spotless and the employees went above and beyond for my fiancée and I. It was a wonderful stay and we look forward to staying again in the future. There is lots of food to choose from at Ameristar. Not to mention there is lots of fun to be had. We personally played the slots, ate dinner before that and after all of that we enjoyed the sparkling clean pool and hot tub at the hotel. It waa a wonderful stay and we definitely look forward to staying again.
Reviewed on Feb 6, 2026
MainStay Suites St. Louis - Galleria
Price was CA $1,768, price is now CA $1,360 per person
CA $1,360
per person
Mar 20 - Mar 22
found 2 days ago
Roundtrip flight included
Saskatoon (YXE) to St. Louis (STL)
6.6/10 (41 reviews)
The staff, everyone was compassionate and very accommodating!
Reviewed on Feb 2, 2026
Defiance Hotel Deals
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Feb 9 to Feb 10
CA $122
CA $141 total
Feb 9 - Feb 10
includes taxes & fees
7.8/10 Good! (1,091 reviews)
Great room, great people, great breakfast
Reviewed on Feb 2, 2026
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is CA $178 per night from Feb 16 to Feb 17
CA $178
CA $227 total
Feb 16 - Feb 17
includes taxes & fees
8.4/10 Very Good! (2,225 reviews)
Everything was very, very nice. The casino smoke was unfortunate, but was not noticable in the room, of course.
Reviewed on Feb 7, 2026
The Wildwood Hotel
2801 Fountain Pl Wildwood MO
Fully refundableReserve now, pay when you stay
The price is CA $111 per night from Feb 9 to Feb 10
CA $111
CA $129 total
Feb 9 - Feb 10
includes taxes & fees
9.2/10 Wonderful! (1,626 reviews)
Clean room and easy parking.
Reviewed on Feb 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Defiance
Busch Stadium
5/5(19 reviews)
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
4.5/5(37 reviews)
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
4.5/5(7 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
What to do in Defiance
St Louis Self-Guided Driving and Walking Audio Tour
CA $23
per traveller
St. Louis Ghost Tour: Sinister Sins & Shadows
CA $44
per adult
St. Louis Small Group Tour with St. Louis Arch & River Cruise
CA $196
per adult
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
