Defiance Vacation Packages

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Your Defiance Vacation

Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a vacation package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Center and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance vacation is just a few clicks away with Expedia.

Top Defiance Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $785, price is now CA $595 per person
CA $595
per person
Oct 28 - Oct 30
found 6 hours ago
Roundtrip flight included
Halifax (YHZ) to St. Louis (STL)
9.2/10 Wonderful! (1,558 reviews)
Loved the room, pretty good breakfast in the morning lots of options.

Reviewed on Aug. 20, 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was CA $996, price is now CA $824 per person
CA $824
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.4/10 Very Good! (1,001 reviews)
Loved my stay here will be back

Reviewed on Aug. 13, 2025

CentralWestEnd-WashU-STL- Euphoria

CentralWestEnd-WashU-STL- Euphoria

2 out of 5
Central West End
Price was CA $2,103, price is now CA $1,766 per person
CA $1,766
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
10/10 Exceptional! (1 review)
Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed

4 out of 5
Central West End
Price was CA $1,304, price is now CA $1,098 per person
CA $1,098
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (9 reviews)
Overall, we loved the apartment. It was cute, beds were very comfortable.

Reviewed on May 8, 2025

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4 out of 5
Central West End
Price was CA $847, price is now CA $717 per person
CA $717
per person
Oct 10 - Oct 12
found 1 day ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.2/10 Very Good! (1,000 reviews)
Everything is good except the odor in the hall ways

Reviewed on Aug. 17, 2025

Ready to book your vacation to Defiance?

 

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Defiance Hotel Deals

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $153 per night from Aug 27 to Aug 28
CA $153
CA $199 total
Aug 27 - Aug 28
includes taxes & fees
8.2/10 Very Good! (2,068 reviews)
"We stayed"

Reviewed on Aug. 17, 2025

Hollywood Casino & Hotel St. Louis
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

3 out of 5
1088 South Highway Drive, Fenton, MO
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Aug 31 to Sep 1
CA $124
CA $143 total
Aug 31 - Sep 1
includes taxes & fees
8.2/10 Very Good! (1,007 reviews)
"Very friendly staff. Pool was amazing and the breakfast was awesome"

Reviewed on Aug. 20, 2025

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

3 out of 5
13639 Riverport Dr, Maryland Heights, MO
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from Sep 18 to Sep 19
CA $101
CA $118 total
Sep 18 - Sep 19
includes taxes & fees
7.2/10 Good! (1,024 reviews)
"Excellent customer service…very friendly staff"

Reviewed on Aug. 17, 2025

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
See all 830 properties in Defiance
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Discover the most popular places to visit in Defiance

Busch Stadium

Busch Stadium

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Busch Stadium
Gateway Arch featuring modern architecture, a city and a skyscraper

Gateway Arch

Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Gateway Arch
St. Louis Zoo

St. Louis Zoo

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

St. Louis Zoo

What to do in Defiance

St Louis: City Museum General Admission Ticket

St Louis: City Museum General Admission Ticket

CA $31
per adult
96% of travellers recommend
St Louis: City Museum General Admission Ticket
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour

CA $44
per adult
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Best of St. Louis Small Group Tour w/ Arch & River Cruise

Best of St. Louis Small Group Tour w/ Arch & River Cruise

CA $233
per adult
84% of travellers recommend
Best of St. Louis Small Group Tour w/ Arch & River Cruise
See all activities in Defiance

Frequently asked questions

How much does a Defiance vacation package cost?
You can grab a vacation package to this destination from CA $595 on Expedia. However, how much your vacation to Defiance costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Defiance?
The off-season is the best time to travel to Defiance if you're hoping to keep costs down. Another tip for getting cheap Defiance vacation packages? Avoid visiting during public holidays and any major festivals.
How many days is enough for Defiance?
The ideal duration for your Defiance vacation depends on what you'd like to do and see. Usually, a few days to a week will give you time to go to all the major attractions and discover some hidden spots along the way.
How to find the best Defiance package deals?
Begin your search for a Defiance package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Defiance package deal straight away, just play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Defiance getaway off to a flying start.
Is it cheaper to book a Defiance vacation as a package?
You can enjoy significant savings on your next Defiance retreat by booking a personalized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Defiance?
If you've got your Defiance vacation dates locked in, book as early as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment trips? Our last-minute deals are great for travelling on a whim.
How to plan a trip to Defiance?

  1. Choose your dates: The things you'd like to do in Defiance and your favourite season can help you decide when to get away.
  2. Set a budget: Factor in expenses like flights, transportation and food when working out how much to save for your trip to Defiance. Then, pick a property that works with your budget, whether that's a low-cost stay or a lavish retreat.
  3. Decide how many days away: Start by listing all the activities and attractions you'd like to get to in Defiance. Then, estimate how long you'll need for each, as well as any travel time.
  4. Bundle your bookings: With your travel dates in order, you can combine your hotels, flights, car rental and more into a tailored Defiance vacation package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.