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Flight and Pet-friendly hotel deals in Southeastern Indiana

Price found within the past 48 hours. Click for updated prices.

21c Museum Hotel Louisville

Downtown Louisville

CA $1,535

per person

Sep 18 - Sep 21

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Louisville (SDF)

9.4/10 Exceptional! (1,003 reviews)

This is meant to be the flagship 21C and it was at one time, but it has started to fray at the edges noticably.. having stayed at the Lexington location recently I was saddened by the fallen state of the flagship. Even the gift shop was ramshackle. The peguins have all faded.. the room decor was tatty.. what was the meaning of what looked to landuary netting stappled over the beds? It felt like some charity shop try hard highschool art project. The bathroom lights were gloomy.. its simply a sad state of affairs. and considering the boom of small chic hotels in nearby hipper locations .. the 21c Louisville needs to step back into what they started as and bring it. They were the first.. let it not be on its last leg

Reviewed on Aug 6, 2026

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3 Night Pet-friendly holidays in Southeastern Indiana

Price found within the past 48 hours. Click for updated prices.

21c Museum Hotel Louisville

Downtown Louisville

CA $1,535

per person

Sep 18 - Sep 21

found 1 day ago

Roundtrip non-stop flight included

Toronto (YTO) to Louisville (SDF)

9.4/10 Exceptional! (1,003 reviews)

This is meant to be the flagship 21C and it was at one time, but it has started to fray at the edges noticably.. having stayed at the Lexington location recently I was saddened by the fallen state of the flagship. Even the gift shop was ramshackle. The peguins have all faded.. the room decor was tatty.. what was the meaning of what looked to landuary netting stappled over the beds? It felt like some charity shop try hard highschool art project. The bathroom lights were gloomy.. its simply a sad state of affairs. and considering the boom of small chic hotels in nearby hipper locations .. the 21c Louisville needs to step back into what they started as and bring it. They were the first.. let it not be on its last leg

Reviewed on Aug 6, 2026

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See all available trips from Columbus to Southeastern Indiana

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4 Night Pet-friendly holidays in Southeastern Indiana

Price found within the past 48 hours. Click for updated prices.

Birch Hill Suites Clarksville-Louisville North

CA $966

per person

Oct 8 - Oct 12

found 14 hours ago

Roundtrip non-stop flight included

Ottawa (YOW) to Louisville (SDF)

7.4/10 Good! (329 reviews)

Aloft by Marriott Louisville Downtown

Downtown Louisville

CA $1,403

per person

Oct 8 - Oct 12

found 16 hours ago

Roundtrip flight included

Edmonton (YEG) to Louisville (SDF)

9/10 Wonderful! (1,006 reviews)

I love this hotel. It's my preferred stay when in Louisville. The staff, the rooms the lobby bar. The place is great

Reviewed on Aug 6, 2026

Residence Inn by Marriott Louisville Downtown

Downtown Louisville

CA $1,332

per person

Oct 8 - Oct 12

found 16 hours ago

Roundtrip flight included

Edmonton (YEG) to Louisville (SDF)

8.8/10 Excellent! (1,003 reviews)

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Pet-friendly Hotels in Southeastern Indiana

Galt House Hotel Trademark Collection by Wyndham

140 North Fourth Street Louisville KY

5 min walk from Kentucky International Convention Center

Book a stay at this spa hotel in Louisville. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the restaurant and the helpful staff ...

9/10 Wonderful! (4,234 reviews)

"Great location"

Reviewed on Aug 6, 2026

Omni Louisville Hotel

400 S. 2nd Street Louisville KY

4 min walk from Kentucky International Convention Center

Book a stay at this spa hotel in Louisville. Enjoy a full-service spa, 3 restaurants, and 3 bars/lounges. Our guests praise the helpful staff and the clean rooms ...

Holiday Inn Louisville Downtown by IHG

101 W. Muhammad Ali Blvd Louisville KY

7 min walk from Kentucky International Convention Center

Stay at this hotel in Louisville. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms ...

See all 1,140 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.